Arnolol
- CAS No.
- 87129-71-3
- Chemical Name:
- Arnolol
- Synonyms
- Arnolol;3-Amino-1-[4-(2-methoxyethyl)phenoxy]-3-methylbutan-2-ol;2-Butanol, 3-amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-;1-[4-(2-methoxyethyl)-phenoxy]-3-amino-3-methyl-butan-2-ol
- CBNumber:
- CB2875769
- Molecular Formula:
- C14H23NO3
- Molecular Weight:
- 253.34
- MDL Number:
- MFCD00868795
- MOL File:
- 87129-71-3.mol
- MSDS File:
- SDS
| FDA UNII | 98HS077RUP |
|---|
Arnolol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA004OQQ | 3-Amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-2-butanol 95% | 87129-71-3 | 25mg | $800 | 2026-05-28 | Buy |
| aablocks | AA004OQQ | 3-Amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-2-butanol 95% | 87129-71-3 | 100mg | $1569 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD277985 | 3-Amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-2-butanol 95% | 87129-71-3 | 5MG | $320 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD277985 | 3-Amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-2-butanol 95% | 87129-71-3 | 25MG | $835 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD277985 | 3-Amino-1-[4-(2-methoxyethyl)phenoxy]-3-methyl-2-butanol 95% | 87129-71-3 | 100MG | $1665 | 2026-05-27 | Buy |
Arnolol Chemical Properties, Uses, Production
Originator
Arnolol,ZYF Pharm Chemical
Uses
Arnolol is a beta blocker with a pressure-lowering action[1].
Manufacturing Process
2 methods of producing of 1-[4-(2-methoxyethyl)-phenoxy]-3-amino-3-
methyl-butan-2-ol:
1). 19.0 g of 1-[4-(2-methoxyethyl)phenoxy]-3-nitro-3-methylbutan-2-ol are
hydrogenated at 60°C and under a pressure of 6 bar in a mixture of 250 ml of
ethanol and 50 ml of glacial acetic acid in the presence of 4.0 g of palladiumon-
charcoal (10% Pd). After the mixture has been filtered and the solvent has
been evaporated off, the residue is rendered alkaline with 2 N NaOH and the mixture is extracted with CH2Cl2. The organic phase is washed with water and
dried with Na2SO4 to give, after evaporation, 15.0 g of the 1-[4-(2-
methoxyethyl)phenoxy]-3-amino-3-methylbutan-2-ol, melting point 120°-
122°C (dec.).
2). 18.3 g of zinc dust are gradually added to 20.0 g of 1-[4-(2-methoxyethyl)
phenoxy]-3-nitro-3-methylbutan-2-ol in 400 ml of ethanol and 60 ml of
concentrated hydrochloric acid at 50°-60°C. The mixture is stirred at this
temperature for 1 h and filtered and the solvent is evaporated off. After 200
ml of 40% strength NaOH have been added, the product is extracted with
methylene chloride. Solvent is distilled and the 1-[4-(2-methoxyethyl)
phenoxy]-3-amino-3-methylbutan-2-ol is produced, melting point 120°-122°C
(dec.).
Therapeutic Function
Beta-adrenergic blocker (ophthalmic)
References
[1] P Ashton, et al. The effect of chlorhexidine acetate on the corneal penetration of sorbitol from an arnolol formulation in the albino rabbit. J Ocul Pharmacol. 1990 Spring;6(1):37-42. DOI:10.1089/jop.1990.6.37
Arnolol Preparation Products And Raw materials
Raw materials
Preparation Products
Arnolol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | 13186333400 19299362551 | cuichengbio@163.com | China | 1931 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 9995 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
87129-71-3 (Arnolol) Related Search:
1of4
