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1-(4-bromophenyl)-2-chloroethan-1-one

CAS No.
4209-02-3
Chemical Name:
1-(4-bromophenyl)-2-chloroethan-1-one
Synonyms
p-Bromo-2-chloroacetophenone;4'-Bromo-α-chloroacetophenone;2-chloro-4'-bromoacetophenone;4'-Bromo-2-Chloroacetophenone;Ethanone, 1-(4-bromophenyl)-2-chloro-;1-(4-bromophenyl)-2-chloroethan-1-one
CBNumber:
CB2928168
Molecular Formula:
C8H6BrClO
Molecular Weight:
233.49
MDL Number:
MFCD00095178
MOL File:
4209-02-3.mol
MSDS File:
SDS
Last updated:2026-05-28 00:52:12

1-(4-bromophenyl)-2-chloroethan-1-one Properties

Melting point 119-120 °C
Boiling point 306.7±22.0 °C(Predicted)
Density 1.571±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
Appearance White to off-white Solid
InChI InChI=1S/C8H6BrClO/c9-7-3-1-6(2-4-7)8(11)5-10/h1-4H,5H2
InChIKey HCQNNQFCUAGJBD-UHFFFAOYSA-N
SMILES C(=O)(C1=CC=C(Br)C=C1)CCl

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  Xn

1-(4-bromophenyl)-2-chloroethan-1-one price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B6354 1-(4-Bromophenyl)-2-chloroethan-1-one min. 98.0 % 4209-02-3 5G $29 2026-04-30 Buy
TCI Chemical B6354 1-(4-Bromophenyl)-2-chloroethan-1-one min. 98.0 % 4209-02-3 25G $78 2026-04-30 Buy
Matrix Scientific 119241 1-(4-Bromophenyl)-2-chloroethanone 4209-02-3 1.00g $90 2026-05-18 Buy
Matrix Scientific 119241 1-(4-Bromophenyl)-2-chloroethanone 4209-02-3 5.00g $288 2026-05-18 Buy
Matrix Scientific 119241 1-(4-Bromophenyl)-2-chloroethanone 4209-02-3 10.00g $486 2026-05-18 Buy
Product number Packaging Price Buy
B6354 5G $29 Buy
B6354 25G $78 Buy
119241 1.00g $90 Buy
119241 5.00g $288 Buy
119241 10.00g $486 Buy

1-(4-bromophenyl)-2-chloroethan-1-one Chemical Properties, Uses, Production

Uses

2-Chloro-4''-bromoacetophenone

Synthesis

4'-Bromoacetophenone

99-90-1

1-(4-bromophenyl)-2-chloroethan-1-one

4209-02-3

General procedure for the synthesis of 2'-chloro-4-bromoacetophenone from p-bromoacetophenone: [TABLE-US-00002] (18) Acetophenone Derivative R13 R14 1 NO2 H 2 NO2 Cl 3 H Br 4 H H. Acetophenone derivatives shown in Eqn. (18) (2.00 g) was dissolved or suspended in a solvent, and sulfonyl chloride as shown in Table 2 was added in a single addition under stirring (molar concentration M based on acetophenone derivative). The reaction temperature and reaction time are shown in Table 2. [Table-US-00003] Table 2: Acetophenone derivatives, SO2Cl2 (equivalent), solvent (M), temperature, time (hr) and yield (%). Examples: 42 MTBE(0.5)1 3.0 room temperature 4.5 50.8; 43 MTBE(1)1 1.65 reflux 7.0 70.1; 44 IPE(1)1 3.0 room temperature 3.0 77.8; 45 DME(1)1 1.65 room temperature 4.0 71.4; 46 MTBE(1)3 3.0 room temperature 1.0 50.3; 47 MTBE(1)4 1.1 room temperature 7.0 78.9. Note: MTBE is methyl tert-butyl ether; IPE is diisopropyl ether; DME is 1,2-dimethoxyethane.

References

[1] Synthesis, 1988, # 7, p. 545 - 546
[2] Synthetic Communications, 2006, vol. 36, # 2, p. 255 - 258
[3] Green Chemistry, 2009, vol. 11, # 2, p. 275 - 278
[4] Synthetic Communications, 2011, vol. 41, # 10, p. 1508 - 1513
[5] Tetrahedron Letters, 2004, vol. 45, # 1, p. 191 - 193

41262-33-3
4209-02-3
881650-48-2
Synthesis of 1-(4-bromophenyl)-2-chloroethan-1-one from Ethanone, 1-(4-bromophenyl)-2,2,2-trichloro-
Global Suppliers ( 106)
Supplier Tel Email Country ProdList Advantage
Changzhou Ditong chemical Co.,Ltd. 0519-88298848 18118010980 info@edengenechem.com China 622 58
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. 021-69106960 13701823997 13701823733@163.com China 4634 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Beijing Holiyang Chemical Co. Ltd. 13718199399 holiyangchem@163.com China 3271 56
Shanghai YouPeng Chemical Co. Ltd. 021-69005955 13701776567; youpengchem@163.com China 4153 56
Sichuan Hainuowei Technology Co. Ltd. 13708085536 13708085536 hanovichem@163.com China 3268 56

View Latest Price from 1-(4-bromophenyl)-2-chloroethan-1-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-4'-bromoacetophenone pictures 2026-09-18 2-Chloro-4'-bromoacetophenone
4209-02-3
$5.00 1kg ≥99% 500mt/year Jinan Finer Chemical Co., Ltd
2-Chloro-4'-bromoacetophenone pictures 2026-08-07 2-Chloro-4'-bromoacetophenone
4209-02-3
$1.00-35.00 1KG 99% 15000KG Shaanxi Dideu Medichem Co. Ltd
1-(4-bromophenyl)-2-chloroethan-1-one pictures 2026-05-28 1-(4-bromophenyl)-2-chloroethan-1-one
4209-02-3
$10.00 1KG 99.% 10 ton Hebei Chuanghai Biotechnology Co,.LTD

1-(4-bromophenyl)-2-chloroethan-1-one Spectrum

1-(4-bromophenyl)-2-chloroethan-1-one 4'-Bromo-α-chloroacetophenone p-Bromo-2-chloroacetophenone Ethanone, 1-(4-bromophenyl)-2-chloro- 4'-Bromo-2-Chloroacetophenone 2-chloro-4'-bromoacetophenone 4209-02-3