1-(4-bromophenyl)-2-chloroethan-1-one
- CAS No.
- 4209-02-3
- Chemical Name:
- 1-(4-bromophenyl)-2-chloroethan-1-one
- Synonyms
- p-Bromo-2-chloroacetophenone;4'-Bromo-α-chloroacetophenone;2-chloro-4'-bromoacetophenone;4'-Bromo-2-Chloroacetophenone;Ethanone, 1-(4-bromophenyl)-2-chloro-;1-(4-bromophenyl)-2-chloroethan-1-one
- CBNumber:
- CB2928168
- Molecular Formula:
- C8H6BrClO
- Molecular Weight:
- 233.49
- MDL Number:
- MFCD00095178
- MOL File:
- 4209-02-3.mol
- MSDS File:
- SDS
| Melting point | 119-120 °C |
|---|---|
| Boiling point | 306.7±22.0 °C(Predicted) |
| Density | 1.571±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C8H6BrClO/c9-7-3-1-6(2-4-7)8(11)5-10/h1-4H,5H2 |
| InChIKey | HCQNNQFCUAGJBD-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=CC=C(Br)C=C1)CCl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H319-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xn |
1-(4-bromophenyl)-2-chloroethan-1-one price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6354 | 1-(4-Bromophenyl)-2-chloroethan-1-one min. 98.0 % | 4209-02-3 | 5G | $29 | 2026-04-30 | Buy |
| TCI Chemical | B6354 | 1-(4-Bromophenyl)-2-chloroethan-1-one min. 98.0 % | 4209-02-3 | 25G | $78 | 2026-04-30 | Buy |
| Matrix Scientific | 119241 | 1-(4-Bromophenyl)-2-chloroethanone | 4209-02-3 | 1.00g | $90 | 2026-05-18 | Buy |
| Matrix Scientific | 119241 | 1-(4-Bromophenyl)-2-chloroethanone | 4209-02-3 | 5.00g | $288 | 2026-05-18 | Buy |
| Matrix Scientific | 119241 | 1-(4-Bromophenyl)-2-chloroethanone | 4209-02-3 | 10.00g | $486 | 2026-05-18 | Buy |
1-(4-bromophenyl)-2-chloroethan-1-one Chemical Properties, Uses, Production
Uses
2-Chloro-4''-bromoacetophenone
Synthesis
99-90-1
4209-02-3
General procedure for the synthesis of 2'-chloro-4-bromoacetophenone from p-bromoacetophenone: [TABLE-US-00002] (18) Acetophenone Derivative R13 R14 1 NO2 H 2 NO2 Cl 3 H Br 4 H H. Acetophenone derivatives shown in Eqn. (18) (2.00 g) was dissolved or suspended in a solvent, and sulfonyl chloride as shown in Table 2 was added in a single addition under stirring (molar concentration M based on acetophenone derivative). The reaction temperature and reaction time are shown in Table 2. [Table-US-00003] Table 2: Acetophenone derivatives, SO2Cl2 (equivalent), solvent (M), temperature, time (hr) and yield (%). Examples: 42 MTBE(0.5)1 3.0 room temperature 4.5 50.8; 43 MTBE(1)1 1.65 reflux 7.0 70.1; 44 IPE(1)1 3.0 room temperature 3.0 77.8; 45 DME(1)1 1.65 room temperature 4.0 71.4; 46 MTBE(1)3 3.0 room temperature 1.0 50.3; 47 MTBE(1)4 1.1 room temperature 7.0 78.9. Note: MTBE is methyl tert-butyl ether; IPE is diisopropyl ether; DME is 1,2-dimethoxyethane.
References
[1] Synthesis, 1988, # 7, p. 545 - 546
[2] Synthetic Communications, 2006, vol. 36, # 2, p. 255 - 258
[3] Green Chemistry, 2009, vol. 11, # 2, p. 275 - 278
[4] Synthetic Communications, 2011, vol. 41, # 10, p. 1508 - 1513
[5] Tetrahedron Letters, 2004, vol. 45, # 1, p. 191 - 193



1-(4-bromophenyl)-2-chloroethan-1-one Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ditong chemical Co.,Ltd. | 0519-88298848 18118010980 | info@edengenechem.com | China | 622 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. | 021-69106960 13701823997 | 13701823733@163.com | China | 4634 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| Beijing Holiyang Chemical Co. Ltd. | 13718199399 | holiyangchem@163.com | China | 3271 | 56 |
| Shanghai YouPeng Chemical Co. Ltd. | 021-69005955 13701776567; | youpengchem@163.com | China | 4153 | 56 |
| Sichuan Hainuowei Technology Co. Ltd. | 13708085536 13708085536 | hanovichem@163.com | China | 3268 | 56 |
View Latest Price from 1-(4-bromophenyl)-2-chloroethan-1-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-18 | 2-Chloro-4'-bromoacetophenone
4209-02-3
|
$5.00 | 1kg | ≥99% | 500mt/year | Jinan Finer Chemical Co., Ltd | |
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2026-08-07 | 2-Chloro-4'-bromoacetophenone
4209-02-3
|
$1.00-35.00 | 1KG | 99% | 15000KG | Shaanxi Dideu Medichem Co. Ltd | |
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2026-05-28 | 1-(4-bromophenyl)-2-chloroethan-1-one
4209-02-3
|
$10.00 | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD |
-

- 2-Chloro-4'-bromoacetophenone
4209-02-3
- $5.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-

- 2-Chloro-4'-bromoacetophenone
4209-02-3
- $1.00-35.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- 1-(4-bromophenyl)-2-chloroethan-1-one
4209-02-3
- $10.00
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD





