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4-Bromophenylacetylene

4-Bromophenylacetylene Structure
4-Bromophenylacetylene structure
CAS No.
766-96-1
Chemical Name:
4-Bromophenylacetylene
Synonyms
1-BROMO-4-ETHYNYLBENZENE;(4-BromphenyL;4-BROMOPHENYLACETYLENE;(4-BroMphenyl)acetylene;4'-BROMOPHENYL ACETYLENE;1-ETHYNYL-4-BROMOBENZENE;4-Bromophenylacetylene 98%;Benzene, 1-broMo-4-ethynyl-;(4-BROMPHENYL)-ACETYLEN 97%;1-Bromo-4-ethynylbenzene >
CBNumber:
CB7440678
Molecular Formula:
C8H5Br
Molecular Weight:
181.03
MDL Number:
MFCD00168822
MOL File:
766-96-1.mol
MSDS File:
SDS
Last updated:2026-05-28 03:36:22
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4-Bromophenylacetylene Properties

Melting point 64-67 °C(lit.)
Boiling point 88-90°C 16mm
Density 1.4255 (rough estimate)
refractive index 1.6411 (estimate)
Flash point 88-90°C/16mm
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Soluble in chloroform, diethyl ether and ethanol.
form Powder, Crystalline Powder or Solid
color White to yellow
BRN 1209726
InChI InChI=1S/C8H5Br/c1-2-7-3-5-8(9)6-4-7/h1,3-6H
InChIKey LTLVZQZDXQWLHU-UHFFFAOYSA-N
SMILES C1(Br)=CC=C(C#C)C=C1
CAS DataBase Reference 766-96-1(CAS DataBase Reference)
NIST Chemistry Reference Benzene, 1-bromo-4-ethynyl-(766-96-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H411
Precautionary statements  P264-P270-P273-P301+P312-P391-P501
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,N
Risk Statements  22-51/53
Safety Statements  61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
HazardClass  9
PackingGroup  III
HS Code  29039990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 2
NFPA 704
1
2 0

4-Bromophenylacetylene price More Price(89)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 206512 1-Bromo-4-ethynylbenzene 97% 766-96-1 1g $108 2026-04-30 Buy
TCI Chemical B3701 1-Bromo-4-ethynylbenzene >98.0%(GC) 766-96-1 1g $33 2026-04-30 Buy
TCI Chemical B3701 1-Bromo-4-ethynylbenzene >98.0%(GC) 766-96-1 5g $108 2026-04-30 Buy
Usbiological 264001 4-Bromophenylacetylene Asreported 766-96-1 1g $352 2026-06-03 Buy
Usbiological 264001 4-Bromophenylacetylene Asreported 766-96-1 2g $468 2026-06-03 Buy
Product number Packaging Price Buy
206512 1g $108 Buy
B3701 1g $33 Buy
B3701 5g $108 Buy
264001 1g $352 Buy
264001 2g $468 Buy

4-Bromophenylacetylene Chemical Properties, Uses, Production

Chemical Properties

Off-White Solid

Uses

Starting material for heterocyclotriynes, second-order nonlinear optical materials, and unsymmetrical 1,4-diarylbutadiynes

Uses

4-Bromophenylacetylene, is used as the starting material for second-order nonlinear optical materials, heterocyclotriynes, and unsymmetrical 1,4-diarylbutadiynes.

Uses

1-Bromo-4-ethynylbenzene was used in the synthesis of 1-bromo-4-(4′-tetrahydropyranyloxy-1′-ethynylphenyl)benzene.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 3224, 1989 DOI: 10.1021/jo00274a055
Tetrahedron, 62, p. 6673, 2006 DOI: 10.1016/j.tet.2005.12.077

Synthesis

Under nitrogen protection, 25 mL of triethylamine, 1.415 g (5.0 mmol) of 4-bromoiodobenzene, 420 mg (5.0 mmol) of 2-methyl-3-butyn-2-ol, and 70 mg (0.1 mmol) of bis(triphenylphosphine)palladium dichloride (Pd(PPh3)2Cl2), triphenylphosphine ( PPh3) 105 mg (0.4 mmol), copper iodide (CuI) 38 mg (0.2 mmol), 35 reaction until thin layer chromatography monitoring raw materials on the disappearance of bromoiodobenzene spots as the end point. Reaction solution evaporated solvent under reduced pressure, CH2Cl2 dissolved, washed sequentially with 5% dilute hydrochloric acid, saturated NaCl solution, anhydrous MgSO4 drying, filtration. After the filtrate was evaporated the solvent under reduced pressure, the crude product was purified by column chromatography (eluent: petroleum ether:ethyl acetate=10:1) to obtain 4-(4-bromophenyl)-2-methyl-3-butynyl-2-ol as white solid 1.052 g (4.4 mmol) in 90% yield.
. Under the protection of nitrogen, 30 mL of toluene, 4-(4-bromophenyl)-2-methyl-3-butynyl-2-alcohol 478 mg (2.0 mmol), NaOH 480 mg (12 mmol) and diethylene glycol monoethyl ether 8.6 mL were added to the Schlenk reaction flask, and the reaction was carried out at 75 until the disappearance of spots of raw materials was monitored by thin-layer chromatography as the end point. Cooled to room temperature, washed sequentially with 5% dilute hydrochloric acid, saturated NaCl solution, anhydrous MgSO4 drying, filtration. After the filtrate was evaporated to dry the solvent under reduced pressure, the crude product was purified by column chromatography (eluent petroleum ether) to give a white solid 319 mg (1.76 mmol). NMR spectra proved that the product was (4-bromophenyl)acetylene in 80% yield.

4-Bromophenylacetylene synthesis

90965-06-3
1122-91-4
766-96-1
Synthesis of 4-Bromophenylacetylene from Dimethyl (1-Diazo-2-oxopropyl)phosphonate and 4-Bromobenzaldehyde

4-Bromophenylacetylene Preparation Products And Raw materials

Raw materials

1-bromo-4-(2,2-dibromovinyl)benzene 1-Bromo-4-(1,2-dibromoethyl)benzene 1,3,3-Trimethyl-2,3-dihydro-1H-indole-2-one 3-(4-Bromo-phenyl)-prop-2-yn-1-ol 4-(4-BroMophenyl)-2-Methylbut-3-yn-2-ol
2,3-Dibromo-2-(4-bromophenyl)propionic acid (4-Bromophenylethynyl)trimethylsilane

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Preparation Products

1-(4-Bromophenyl)-naphthlene 4'-Diethylaminophenyl acetylene 4-Bromo diphenylacetylene 1-(4-bromophenyl)-2-chloroethan-1-one 3-(4-Bromophenyl)-4'-methylpropiophenone
3-(4-Bromophenyl)propiolic Acid

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4-Bromophenylacetylene Suppliers

Global Suppliers ( 280)
Supplier Tel Email Country ProdList Advantage
Shanghai Union Medical Technology Co. Ltd. 13120563767 chemchen925@outlook.com China 624 58
Shanghai Jinyuanrui Pharmaceutical Technology Co., Ltd 021-18217523 18217523428 jinrui750315@126.com China 488 58
Jiangxi Jingyang Chemical Products Co., LTD 0798-15170312128 15170312128 1436027029@qq.com China 16 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Shanghai Union Medical Technology Co. Ltd. 58
Shanghai Jinyuanrui Pharmaceutical Technology Co., Ltd 58
Jiangxi Jingyang Chemical Products Co., LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Energy Chemical 61

View Latest Price from 4-Bromophenylacetylene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromophenylacetylene pictures 2026-09-16 4-Bromophenylacetylene
766-96-1
 $7.00-139.00 5g 0.98 25kg Shanghai UCHEM Inc.
4-Bromophenylacetylene pictures 2026-09-02 4-Bromophenylacetylene
766-96-1
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
4-Bromophenylacetylene pictures 2021-09-23 4-Bromophenylacetylene
766-96-1
 100g 99% 25kg, 50kg Zhengzhou HQ Material CO.,LTD.

4-Bromophenylacetylene Spectrum

4-Bromophenylacetylene(766-96-1)1HNMR4-Bromophenylacetylene(766-96-1)IR

766-96-1 (4-Bromophenylacetylene) Related Search:

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1-Bromo-3-ethynyl-benzene 1-Bromo-2-ethynylbenzene 1-[2-(4-Bromophenyl)ethynyl]-2-fluoro-4-pentylbenzene 4-Bromo-1-ethynyl-2-fluorobenzene 96 3-(4-Bromo-phenyl)-prop-2-yn-1-ol
2-[(4-Bromophenyl)ethynyl] thiophene 4-Bromophenylacetylene acetylene

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(4-BROMPHENYL)-ACETYLEN 97% (4-Bromophenyl)acetylene,97% (4-BroMphenyl)acetylene 4'-BROMOPHENYL ACETYLENE 4-BROMOPHENYLACETYLENE Benzene, 1-broMo-4-ethynyl- (4-BroMphenyl)acetylene, 95+% 1-Bromo-4-ethynylbenzene 97% 1-ETHYNYL-4-BROMOBENZENE 4-Bromophenylacetylene 98% 1-Bromo-4-ethynylbenzene > (4-BromphenyL 4-Bromophenylacetylene ISO 9001：2015 REACH 1-Bromo-4-ethynylbenzene, 98%, 1-Bromo-4-ethynylbenzene - [B47528] 1-BROMO-4-ETHYNYLBENZENE 766-96-1 66-96-1 HC8801CC6H4Br HCCC6H4Br Organic Building Blocks Halogenated Hydrocarbons Alkynyl Building Blocks Aromatic Halides (substituted) pharmacetical Aromatics Compounds Aromatics Alkynyl Halogenated Hydrocarbons Organic Building Blocks