ChemicalBook >> CAS DataBase List >>2-CHLORO-4-METHOXYPHENOL

2-CHLORO-4-METHOXYPHENOL

CAS No.
18113-03-6
Chemical Name:
2-CHLORO-4-METHOXYPHENOL
Synonyms
2-CHLORO-4-METHOXYPHENOL;3-CHLORO-4-HYDROXYANISOLE;2-chloro-4-methoxylphenol;Phenol, 2-chloro-4-methoxy-;2-Chloro-4-methoxyphenol,97%;2-Chloro-4-methoxyphenol >2-Chloro-4-Methoxyphenol, 97% 5GR;2-Chlorohydroquinonemonomethylether;3-Chloro-4-hydroxyanisole, 2-Chloro-p-guaiacol
CBNumber:
CB3100611
Molecular Formula:
C7H7ClO2
Molecular Weight:
158.58
MDL Number:
MFCD00070773
MOL File:
18113-03-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:53:28
Product description Number Pack Size Price
2-Chloro-4-methoxyphenol 98% 412007 5g $73.2
2-Chloro-4-methoxyphenol >98.0%(GC) C1487 5g $149
2-Chloro-4-methoxyphenol >98.0%(GC) C1487 25g $522
2-Chloro-4-methoxyphenol Asreported 269206 50g $694
2-Chloro-4-methoxyphenol Asreported 269206 100g $1062
More product size

2-CHLORO-4-METHOXYPHENOL Properties

Melting point 41-44 °C(lit.)
Boiling point 241°C (rough estimate)
Density 1.153 g/mL at 25 °C(lit.)
Flash point 185 °F
storage temp. Sealed in dry,2-8°C
form Crystalline Low Melting Solid
pka 8.98±0.18(Predicted)
Specific Gravity 1.153
color White to light yellow
BRN 1936412
InChI 1S/C7H7ClO2/c1-10-5-2-3-7(9)6(8)4-5/h2-4,9H,1H3
InChIKey GNVRRKLFFYSLGT-UHFFFAOYSA-N
SMILES COc1ccc(O)c(Cl)c1
CAS DataBase Reference 18113-03-6(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302-H312
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280h
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
Hazard Note  Irritant
HS Code  29071990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-CHLORO-4-METHOXYPHENOL price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 412007 2-Chloro-4-methoxyphenol 98% 18113-03-6 5g $73.2 2023-01-07 Buy
TCI Chemical C1487 2-Chloro-4-methoxyphenol >98.0%(GC) 18113-03-6 5g $149 2026-04-30 Buy
TCI Chemical C1487 2-Chloro-4-methoxyphenol >98.0%(GC) 18113-03-6 25g $522 2026-04-30 Buy
Usbiological 269206 2-Chloro-4-methoxyphenol Asreported 18113-03-6 50g $694 2026-06-03 Buy
Usbiological 269206 2-Chloro-4-methoxyphenol Asreported 18113-03-6 100g $1062 2026-06-03 Buy
Product number Packaging Price Buy
412007 5g $73.2 Buy
C1487 5g $149 Buy
C1487 25g $522 Buy
269206 50g $694 Buy
269206 100g $1062 Buy

2-CHLORO-4-METHOXYPHENOL Chemical Properties,Uses,Production

Chemical Properties

WHITE TO LIGHT YELLOW CRYST. LOW MELTING SOLID

Synthesis

4,4-DIMETHOXY-2,5-CYCLOHEXADIEN-1-ONE, 96

935-50-2

2-CHLORO-4-METHOXYPHENOL

18113-03-6

General procedure for the synthesis of 2-chloro-4-methoxyphenol from 4,4-dimethoxycyclohexa-2,5-dien-1-one: 4,4-dimethoxycyclohexa-2,5-dien-1-one (1.0 mmol) was added to the reaction vessel, followed by the addition of a solution of 1,4-dioxane in 4N HCl (0.5 mL, 2 mmol) dropwise. The yellow color of the reaction mixture faded rapidly. After completion of the reaction, the solvent was removed by vacuum evaporation. The residue was diluted with ethyl acetate (10 mL) and washed with saturated aqueous NaHCO3 solution (5 mL). The organic layer was dried with anhydrous Na2SO4, filtered and concentrated to give 2-chloro-4-methoxyphenol in 95% yield. If necessary, it can be purified by column chromatography using ethyl acetate/hexane gradient elution.

References

[1] Organic and Biomolecular Chemistry, 2014, vol. 12, # 18, p. 2854 - 2858
[2] Tetrahedron Letters, 2016, vol. 57, # 1, p. 15 - 19

150-76-5
18113-03-6
Synthesis of 2-CHLORO-4-METHOXYPHENOL from 4-Methoxyphenol
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View Lastest Price from 2-CHLORO-4-METHOXYPHENOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLORO-4-METHOXYPHENOL pictures 2019-07-06 2-CHLORO-4-METHOXYPHENOL
18113-03-6
$2.00 1KG 99% Career Henan Chemical Co
3-CHLORO-4-HYDROXYANISOLE 2-CHLORO-4-METHOXYPHENOL 2-Chlorohydroquinonemonomethylether 2-Chloro-4-methoxyphenol,97% 2-chloro-4-methoxylphenol 2-Chloro-4-Methoxyphenol, 97% 5GR 3-Chloro-4-hydroxyanisole, 2-Chloro-p-guaiacol 2-Chloro-4-methoxyphenol > Phenol, 2-chloro-4-methoxy- 18113-03-6 C7H7ClO2 ClC6H3OCH3OH Building Blocks Oxygen Compounds Phenols Organic Building Blocks Aromatic Hydrocarbons (substituted) & Derivatives Phenol&Thiophenol&Mercaptan Anisoles, Alkyloxy Compounds & Phenylacetates Chlorine Compounds Phenols Organic Building Blocks Oxygen Compounds