2-Chloro-4-methylbenzaldehyde
- CAS No.
- 50817-80-6
- Chemical Name:
- 2-Chloro-4-methylbenzaldehyde
- Synonyms
- 2-Chloro-p-tolualdehyde;2-CHLORO-4-METHYLBENZALDEHYDE;Benzaldehyde,2-chloro-4-methyl-;2-Chloro-4-methylbenzaldehyde 97%;3-Chloro-4-formyltoluene, 2-Chloro-p-tolualdehyde;2-CHLORO-4-METHYLBENZALDEHYDE2-CHLORO-4-METHYLBENZALDEHYDE
- CBNumber:
- CB61476389
- Molecular Formula:
- C8H7ClO
- Molecular Weight:
- 154.59
- MDL Number:
- MFCD10703515
- MOL File:
- 50817-80-6.mol
- MSDS File:
- SDS
| Melting point | 27-30°C |
|---|---|
| Boiling point | 100-103 °C(Press: 4 Torr) |
| Density | 1.195±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| Appearance | Light yellow to yellow <27°C Solid,>30°C Liquid |
| InChI | 1S/C8H7ClO/c1-6-2-3-7(5-10)8(9)4-6/h2-5H,1H3 |
| InChIKey | OSPMNRDGMUPWNO-UHFFFAOYSA-N |
| SMILES | [H]C(C1=C(Cl)C=C(C)C=C1)=O |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H335 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 22-37/38-41-51 |
| Safety Statements | 26-39-45 |
| WGK Germany | 3 |
| HS Code | 2913000090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
2-Chloro-4-methylbenzaldehyde price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 776963 | 2-Chloro-4-methylbenzaldehyde 97% | 50817-80-6 | 1g | $57.3 | 2023-06-20 | Buy |
| Apolloscientific | OR30989 | 2-Chloro-4-methylbenzaldehyde >98% | 50817-80-6 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR30989 | 2-Chloro-4-methylbenzaldehyde >98% | 50817-80-6 | 5g | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR30989 | 2-Chloro-4-methylbenzaldehyde >98% | 50817-80-6 | 25g | $113 | 2026-06-04 | Buy |
| Apolloscientific | OR30989 | 2-Chloro-4-methylbenzaldehyde >98% | 50817-80-6 | 100g | $361 | 2026-06-04 | Buy |
2-Chloro-4-methylbenzaldehyde Chemical Properties, Uses, Production
Synthesis
6627-51-6
68-12-2
50817-80-6
GENERAL STEPS: 165 mL (413 mmol) of a hexane solution of 2.5 M n-butyllithium (nBuLi) was slowly added dropwise to 82.2 g (400 mmol) of 4-bromo-3-chlorotoluene dissolved in 400 mL of tetrahydrofuran (THF) over a period of 1 h. The reaction system was required to be cooled to -88 °C. At this temperature, the reaction mixture was stirred continuously for 30 min. Subsequently, 44.0 g (602 mmol) of N,N-dimethylformamide (DMF) was added dropwise over 10 minutes by vigorous stirring. The reaction mixture was stirred overnight at room temperature. After that, 100 mL of water and 400 mL of 3 N hydrochloric acid (HCl) were added to the reaction mixture at 0 °C. The organic layer was separated and the aqueous layer was extracted with dichloromethane (2 x 125 mL). The organic extracts were combined, dried with potassium carbonate (K2CO3), and filtered through a short silica gel 60 (40-63 μm) layer. The silica gel layer was washed with 50 mL of dichloromethane. The organic eluates were combined and evaporated to dryness to give a light orange liquid. The liquid was distilled under vacuum and the fractions with boiling points of 99-102 °C/11 mmHg were collected to give 58.0 g (94% yield) of 2-chloro-4-methylbenzaldehyde as a colorless liquid, which crystallized after standing overnight.
References
[1] Patent: WO2014/96282, 2014, A1. Location in patent: Page/Page column 35
[2] Patent: WO2018/91684, 2018, A1. Location in patent: Page/Page column 73; 74
2-Chloro-4-methylbenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huawei Zhihe Pharmaceutical Technology (Shanghai) Co., Ltd. | 18862951601; 18862951601 | gavinhhbcool@163.com | China | 68 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
View Latest Price from 2-Chloro-4-methylbenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 2-Chloro-4-methylbenzaldehyde
50817-80-6
|
$1.00 | 1KG | 98% | 10 tons | Career Henan Chemical Co |
-
- 2-Chloro-4-methylbenzaldehyde
50817-80-6
- $1.00
- 98%
- Career Henan Chemical Co
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