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Pyridine-2-carboxamidine

Pyridine-2-carboxamidine Structure
Pyridine-2-carboxamidine structure
CAS No.
52313-50-5
Chemical Name:
Pyridine-2-carboxamidine
Synonyms
Picolinamidine;2-Pyridinecarboxamidine;2-PyridinecarboxiMidaMide
CBNumber:
CB31011602
Molecular Formula:
C6H7N3
Molecular Weight:
121.14
MDL Number:
MFCD05663356
MOL File:
52313-50-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:31
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Pyridine-2-carboxamidine Properties

Boiling point 240.7±32.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 10.68±0.40(Predicted)
Appearance White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H335-H318-H302-H315
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501

Pyridine-2-carboxamidine price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FP151099 Pyridine-2-carboxamidine 52313-50-5 500mg $150 2026-06-04 Buy
Biosynth FP151099 Pyridine-2-carboxamidine 52313-50-5 250mg $150 2026-06-04 Buy
Biosynth FP151099 Pyridine-2-carboxamidine 52313-50-5 100mg $150 2026-06-04 Buy
Activate Scientific AS113789 Picolinimidamide 98% 52313-50-5 1g $259 2026-06-04 Buy
Activate Scientific AS113789 Picolinimidamide 98% 52313-50-5 5g $519 2026-06-04 Buy
Product number Packaging Price Buy
FP151099 500mg $150 Buy
FP151099 250mg $150 Buy
FP151099 100mg $150 Buy
AS113789 1g $259 Buy
AS113789 5g $519 Buy

Pyridine-2-carboxamidine Chemical Properties, Uses, Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 412, 1961 DOI: 10.1021/jo01061a034

Synthesis

2-Cyanopyridine

100-70-9

Lithium bis(trimethylsilyl)amide

4039-32-1

PYRIDINE-2-CARBOXAMIDINE

52313-50-5

Lithium bis(trimethylsilyl)amide (1M tetrahydrofuran solution, 60.5 mL, 60.5 mmol) was slowly added dropwise to a solution of 2-cyanopyridine (3.0 g, 28.8 mmol) in anhydrous ether (30 mL) at 0 °C. The reaction mixture was kept cooled at 0 °C, followed by the addition of 3M hydrochloric acid (54 mL) with continuous stirring for 30 min. After completion of the reaction, water (135 mL) was added for dilution and the organic phase was separated. The aqueous phase was adjusted to pH 14 with saturated aqueous sodium hydroxide and subsequently extracted with dichloromethane (3 times). The organic extracts were combined, dried over anhydrous sodium sulfate and concentrated in vacuum to afford pyridine-2-carboxamidine (1.70 g, 49% yield).

References

[1] Patent: US2012/202806, 2012, A1

Pyridine-2-carboxamidine Preparation Products And Raw materials

Raw materials

2-Cyanopyridine Lithium bis(trimethylsilyl)amide Tetrahydrofuran Water Hydrochloric acid
Diethyl ether

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Preparation Products

6-hydroxy-5-methyl-2-(pyridin-2-yl)-3,4-dihydropyrimidin-4-one 6-Amino-2-(2-pyridinyl)-4(1H)-pyrimidinone ethyl 6-chloro-2-(pyridin-2-yl)pyrimidine-4-carboxylate

Pyridine-2-carboxamidine Suppliers

Global Suppliers ( 35)
Supplier Tel Email Country ProdList Advantage
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9954 58
Changsha Luxing Bio-Chem Technology Co., Ltd. 0731-88827538 15574813303 luxingbc@126.com China 1975 65
Shanghai Boyners Pharm-Tech Co., Ltd. 13817873692 mkt@boynerspharm.com China 1707 55
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589 3321478047@qq.com China 2002 55
parabiochem 025-83453382-8005 sale@parabiochem.com China 9577 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Jiaxing Deyi Chemical Co., Ltd. 86-0573-85866609 18367600069 945717149@qq.com China 9506 58
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Supplier Advantage
Hangzhou Sage Chemical Co., Ltd. 58
Shanghai Xingui Biotechnology Co., Ltd. 58
Changsha Luxing Bio-Chem Technology Co., Ltd. 65
Shanghai Boyners Pharm-Tech Co., Ltd. 55
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 55
parabiochem 55
Amadis Chemical Company Limited 58
Jiaxing Deyi Chemical Co., Ltd. 58
Wuxi AppTec 58
Aikon International Limited 58

Pyridine-2-carboxamidine Spectrum

PYRIDINE-2-CARBOXAMIDINE(52313-50-5)1HNMR

52313-50-5 (Pyridine-2-carboxamidine) Related Search:

2-Pyridylamid oxime Pyridine-2-carboximidamide hydrochloride Imazapyr acid 4-Allyl-3-(2-pyridyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione 3-Chloro-N-(4-chlorobenzyl)-N'-hydroxy-5-(trifluoromethyl)-2-pyridinecarboximidamide
3-Chloro-N-(4-chlorophenyl)-N'-hydroxy-5-(trifluoromethyl)-2-pyridinecarboximidamide [3-Chloro-5-(trifluoromethyl)-2-pyridinyl](4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino)methanone oxime N'-[(4-Nitrobenzyl)oxy]-2-pyridinecarboximidamide 2-(2-[Imino(2-pyridinyl)methyl]hydrazino)-2-oxoacetamide N'-[(2,4-Dichlorobenzyl)oxy]-2-pyridinecarboximidamide
N'-[(2-Chloro-6-fluorobenzyl)oxy]-2-pyridinecarboximidamide 3-(4-Chlorophenyl)-4-imino-6-(2-pyridyl)-1,3,7-trihydro-5,7-diazaquinazoline-2,8-dione N'-[(2,6-Dichlorobenzyl)oxy]-2-pyridinecarboximidamide 3-Chloro-N'-hydroxy-N-(2-propynyl)-5-(trifluoromethyl)-2-pyridinecarboximidamide (4-Benzylpiperazino)[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methanone oxime
[3-Chloro-5-(trifluoromethyl)-2-pyridinyl](morpholino)methanone oxime [3-Chloro-5-(trifluoromethyl)-2-pyridinyl][4-(4-fluorophenyl)piperazino]methanone oxime 3,6-Di(2-pyridinyl)-1,2-dihydro-1,2,4,5-tetraazine

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2-Pyridinecarboxamidine 2-PyridinecarboxiMidaMide Picolinamidine 52313-50-5