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PEROSPIRONE

PEROSPIRONE Structure
PEROSPIRONE structure
CAS No.
150915-41-6
Chemical Name:
PEROSPIRONE
Synonyms
Perospirine;PEROSPIRONE;PEROSPIRONE HCL;[14C]-Perospirone;Perospirone, 10 mM in DMSO;PerospironeQ: What is Perospirone Q: What is the CAS Number of Perospirone;cis-N-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-1,2-cyclohexanedicarboximide;(1R,2S)-N-[4-[4-(1,2-Benzisothiazole-3-yl)-1-piperazinyl]butyl]cyclohexane-1,2-dicarbimide;1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, cis-;(3aα,7aα)-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H-isoindole-1,3(2H)-dione
CBNumber:
CB3101658
Molecular Formula:
C23H30N4O2S
Molecular Weight:
426.58
MDL Number:
MFCD00866669
MOL File:
150915-41-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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PEROSPIRONE Properties

Boiling point 585.452±50.00 °C(Press: 760.00 Torr)(predicted)
Density 1.251±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 7.615±0.10(predicted)
form Solid
color White to Off-White
InChI InChI=1/C23H30N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h3-4,9-10,17-18H,1-2,5-8,11-16H2/t17-,18+
InChIKey FBVFZWUMDDXLLG-HDICACEKNA-N
SMILES C1(=O)[C@]2([H])[C@@]([H])(CCCC2)C(=O)N1CCCCN1CCN(C2C3=C(SN=2)C=CC=C3)CC1 |&1:2,4,r|
FDA UNII N303OK87DT

PEROSPIRONE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0019906 Perospirone 99.03% 150915-41-6 5mg $83 2026-06-04 Buy
ChemScene CS-0019906 Perospirone 99.03% 150915-41-6 10mg $143 2026-06-04 Buy
ChemScene CS-0019906 Perospirone 99.03% 150915-41-6 25mg $312 2026-06-04 Buy
ChemScene CS-0019906 Perospirone 99.03% 150915-41-6 50mg $500 2026-06-04 Buy
ChemScene CS-0019906 Perospirone 99.03% 150915-41-6 100mg $858 2026-06-04 Buy
Product number Packaging Price Buy
CS-0019906 5mg $83 Buy
CS-0019906 10mg $143 Buy
CS-0019906 25mg $312 Buy
CS-0019906 50mg $500 Buy
CS-0019906 100mg $858 Buy

PEROSPIRONE Chemical Properties,Uses,Production

Uses

Perospirone is a white powdery chemical drug used clinically primarily to treat schizophrenia.

Description

Perospirone hydrochloride was launched in Japan as a new treatment of schizophrenia and other psychoses. This structurally-related analog of ziprasidone can be classically prepared by alkylation of 1-(3-benzisothiazolyl)-piperazine with the appropriate N- (chlorobutyl)-succinimide. As a result of an in vitro determination of its binding profile, perospirone demonstrated a high affinity for 5-HT2, 5-HT1A and D2 receptors as well as a significant but lower affinity for DI and al receptors. Interestingly, these differential effects on neurotransmitters with a high in vivo occupancy of 5-HT2A receptors with lower D2 occupancy seems to provide this new agent with a significantly lower propensity for the development of extrapyramidal symptoms (EPS) and tardive schizophrenia, the main sideeffects associated with classical antipsychotic therapy. Furthermore, perospirone exhibited anxiolytic-like effects in animal models. A long-term clinical trial (> 6 months) in a group of patients suffering from schizophrenia demonstrated the efficacy of perospirone over placebo for the treatment of the positive, negative and general symptoms of schizophrenia at doses of 12 mg to 96 mg t.i.d.

Originator

Sumitomo Pharm. (Japan)

Definition

ChEBI: (3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)-1-piperazinyl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione is a N-arylpiperazine.

brand name

Lullan

PEROSPIRONE synthesis

7716-66-7
150915-41-6
Synthesis of PEROSPIRONE from 3-Chloro-1,2-benzisothiazole

PEROSPIRONE Preparation Products And Raw materials

Raw materials

3-Chloro-1,2-benzisothiazole 3-(1-Piperazinyl)-1,2-benzisothiazole

Preparation Products

PEROSPIRONE Suppliers

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Wuxi MinHua Biochem Pharmatech Co.,Ltd. 0510-0510-66903969 13961776301 mrweizhihua@sina.com China 44 58
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2308 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Pure Chemistry Scientific Inc. 62
LGM Pharma 70
BOC Sciences 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Wuxi MinHua Biochem Pharmatech Co.,Ltd. 58
Pharmacodia (Beijing) Co.,Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Chaolan Chemical Technology Center 58
Amadis Chemical Company Limited 58

View Lastest Price from PEROSPIRONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Perospirone pictures 2026-07-27 Perospirone
150915-41-6
 $43.00-143.00 99.45% 10g TargetMol Chemicals Inc.
PEROSPIRONE pictures 2026-06-30 PEROSPIRONE
150915-41-6
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
  • Perospirone pictures
  • Perospirone
    150915-41-6
  • $43.00-143.00
  • 99.45%
  • TargetMol Chemicals Inc.
  • PEROSPIRONE pictures
  • PEROSPIRONE
    150915-41-6
  • $0.00
  • 99%
  • Shaanxi Dideu New Materials Co. Ltd

PEROSPIRONE Spectrum

PEROSPIRONE(150915-41-6)1HNMR

150915-41-6(PEROSPIRONE)Related Search:

Perospirone hydrochloride 1,2-Cyclohexanedicarboximide 1,2-Cyclohexanedicarboximide etisazole PEROSPIRONE
3-Piperazinobenzisothiazole hydrochloride cis-Octahydroisoindole 1,2-Benzisothiazol-3-amine

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PEROSPIRONE PEROSPIRONE HCL 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, (3aR,7aS)-rel- (9CI) 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, cis- cis-N-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-1,2-cyclohexanedicarboximide Perospirine (3aR,7aS)-2-[4-[4-(1,2-benzothiazol-3-yl)-1-piperazinyl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione (1R,2S)-N-[4-[4-(1,2-Benzisothiazole-3-yl)-1-piperazinyl]butyl]cyclohexane-1,2-dicarbimide (3aα,7aα)-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H-isoindole-1,3(2H)-dione (3aS,7aR)-2-[4-[4-(1,2-Benzothiazol-3-Yl)Piperazin-1-Yl]Butyl]-3a,4,5,6,7,7a-Hexahydroisoindole-1,3-Dione [14C]-Perospirone 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, (3aR,7aS)-rel- PerospironeQ: What is Perospirone Q: What is the CAS Number of Perospirone deficits,atypical,Perospirone,SM-9018,Dopamine Receptor,5-hydroxytryptamine Receptor,5-HT Receptor,Orally,SM9018,schizophrenic,disease,Serotonin Receptor,cognitive,Inhibitor,SM 9018,inhibit,antipsychotic Perospirone, 10 mM in DMSO rel-(3aR,7aS)-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H-isoindole-1,3(2H)-dione 150915-41-6 C23H30N4O2S