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Perospirone hydrochloride

Perospirone hydrochloride Structure
Perospirone hydrochloride structure
CAS No.
129273-38-7
Chemical Name:
Perospirone hydrochloride
Synonyms
Lullan;PEROSPIRONE HYDROCHLORIDE HYDRATE;Lulla;sm-9018;D8-Perospirone HCl;2H8]-Perospirone HCl;SM-9018 hydrochloride;PEROSPIRONE HYDROCHLORIDE;Piropilone (hydrochloride);Perospirone HCl hydrate - Bio-X ?
CBNumber:
CB4192563
Molecular Formula:
C23H30N4O2S.ClH
Molecular Weight:
463.04
MDL Number:
MFCD08457543
MOL File:
129273-38-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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Perospirone hydrochloride Properties

Melting point 95-970C
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
InChIKey HIZFAPMOZFYELI-GNXQHMNLNA-N
SMILES C(N1CCN(C2=NSC3C=CC=CC2=3)CC1)CCCN1C([C@@]2([H])CCCC[C@@]2([H])C1=O)=O.Cl |&1:21,27,r|
CAS DataBase Reference 129273-38-7(CAS DataBase Reference)
FDA UNII T884I76TMN
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
WGK Germany  WGK 1
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

Perospirone hydrochloride price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical P2944 Perospirone Hydrochloride 129273-38-7 25MG $107 2026-04-30 Buy
Usbiological P3349-25 Perospirone Hydrochloride Hydrate ≥98.5% 129273-38-7 100mg $389 2026-06-03 Buy
Usbiological P3349-25 Perospirone Hydrochloride Hydrate ≥98.5% 129273-38-7 250mg $701 2026-06-03 Buy
Usbiological P3349-25 Perospirone Hydrochloride Hydrate ≥98.5% 129273-38-7 500mg $984 2026-06-03 Buy
TRC TRC-P288900-10MG Perospirone Hydrochloride Hydrate 10mg $223 2026-06-03 Buy
Product number Packaging Price Buy
P2944 25MG $107 Buy
P3349-25 100mg $389 Buy
P3349-25 250mg $701 Buy
P3349-25 500mg $984 Buy
TRC-P288900-10MG 10mg $223 Buy

Perospirone hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Serotonin (5-HT2) and dopamine (D2) antagonist (SDA).

Biological Activity

Perospirone (SM-9018) is a typical neuroleptic (antipsychotic) agent th at displays high affinity for 5-HT2, D2 and 5-HT1A receptors (Ki = 0.61, 1.4 and 2.9-1.8 nM, respectively), moderate affinity for alpha 1 and D1 receptors (Ki = 17 and 41 nM, respectively), while exhibiting much reduced affinity for alpha 2 (Ki = 408 nM) and little affinity toward muscarinic, opiate, glutamate, phencyclidine, benzodiazepine or GABAA receptors (Ki >1 μM). SM-9018 antagonizes both D2-dependent (e.g. methamphetamine-induced hyperactivity, apomorphine-induced stereotypy) and 5-HT2-mediated (e.g. tryptamine-induced clonic seizure) activities in vivo, while exhibiting very low cataleptogenic and central depressant activities commonly observed with two other neuroleptics, haloperidol and chlorpromazine.

IC 50

5-HT2A Receptor: 0.6 nM (Ki); D2 Receptor: 1.4 nM (Ki); 5-HT1A Receptor: 2.9 nM (Ki); 5-HT1 Receptor: 18 nM (Ki); D1 Receptor: 41 nM (Ki)

Perospirone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Perospirone hydrochloride Suppliers

Global( 211)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhuhai Free Trade Zone Lizhu Synthetic Pharmaceutical Co., Ltd. -- China 23 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
Eastbang Pharmaceuticals Technology Co., Ltd. +86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387 China 454 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Supplier Advantage
Zhuhai Free Trade Zone Lizhu Synthetic Pharmaceutical Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Tianjin heowns Biochemical Technology Co., Ltd. 57
Dalian Meilun Biotech Co., Ltd. 58
BioBioPha Co., Ltd. 65
TargetMol Chemicals Inc. 58
Eastbang Pharmaceuticals Technology Co., Ltd. 58
Quality Control Solutions Ltd. 56
Chengdu HuaXia Chemical Reagent Co. Ltd 58

View Lastest Price from Perospirone hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Perospirone hydrochloride USP/EP/BP pictures 2026-08-20 Perospirone hydrochloride USP/EP/BP
129273-38-7
 $1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited
Perospirone hydrochloride pictures 2026-07-27 Perospirone hydrochloride
129273-38-7
 $38.00-82.00 99.37% 10g TargetMol Chemicals Inc.
Perospirone hydrochloride pictures 2021-07-13 Perospirone hydrochloride
129273-38-7
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

Perospirone hydrochloride Spectrum

Perospirone hydrochloride(129273-38-7)1HNMR

129273-38-7(Perospirone hydrochloride)Related Search:

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PEROSPIRONE HYDROCHLORIDE PEROSPIRONE HYDROCHLORIDE DIHYDRATE 1h-isoindole-1,3(2h)-dione,2-(4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)but monohydrochloride,cis-yl)hexahydro sm-9018 (3aR,7aS)-rel-2-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-1H- isoindole-1,3(2H)-dione Hydrochloride Trihydrate Lulla Perospirone Hydrochloride Trihydrate (3ar,7as)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione hydrochloride SM-9018 hydrochloride (3aR,7aS)-2-(4-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)butyl)hexahydro-1H-isoindole-1,3(2H)-dione hydrochloride Lullan 1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, hydrochloride (1:1), (3aR,7aS)-rel- Perospirone hydrochloride USP/EP/BP 2H8]-Perospirone HCl Piropilone (hydrochloride) Perospirone hydrochloride, 10 mM in DMSO Perospirone HCl hydrate - Bio-X ? rel-(3aR,7aS)-2-(4-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)butyl)hexahydro-1H-isoindole-1,3(2H)-dione hydrochloride D8-Perospirone HCl PEROSPIRONE HYDROCHLORIDE HYDRATE 129273-38-7 12973-38-7 C23H37ClN4O5S C23H30N4O2SHCl C23H30N4O2SHCl2H2O C24H33ClN4O2S Intermediates & Fine Chemicals Pharmaceuticals