Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- CAS No.
- 220731-04-4
- Chemical Name:
- Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- N2-Boc-pyridine-2,5-diamine;tert-Butyl (5-aminopyridin-2-yl);tert-butyl 5-aminopyridin-2-ylcarbamate;ert-butylN-(5-aminopyridin-2-yl)carbamate;tert-Butyl N-(5-aminopyridin-2-yl)carbamate;Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, N-(5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
- CBNumber:
- CB31064815
- Molecular Formula:
- C10H15N3O2
- Molecular Weight:
- 209.24
- MDL Number:
- MFCD11182697
- MOL File:
- 220731-04-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 330.2±27.0 °C(Predicted) |
|---|---|
| Density | 1.202±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 12.19±0.70(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C10H15N3O2/c1-10(2,3)15-9(14)13-8-5-4-7(11)6-12-8/h4-6H,11H2,1-3H3,(H,12,13,14) |
| InChIKey | NHVPESPHUUFULF-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NC1=NC=C(N)C=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H302-H315-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 261162 | (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester Asreported | 220731-04-4 | 50mg | $337 | 2026-06-03 | Buy |
| Usbiological | 261162 | (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester Asreported | 220731-04-4 | 100mg | $462 | 2026-06-03 | Buy |
| Usbiological | 261162 | (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester Asreported | 220731-04-4 | 250mg | $563 | 2026-06-03 | Buy |
| Usbiological | 261162 | (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester Asreported | 220731-04-4 | 500mg | $779 | 2026-06-03 | Buy |
| Usbiological | 261162 | (5-Aminopyridin-2-yl)-carbamic acid tert-butyl ester Asreported | 220731-04-4 | 1g | $1037 | 2026-06-03 | Buy |
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Chemical Properties, Uses, Production
Synthesis
161117-88-0
220731-04-4
General procedure for the synthesis of tert-butyl (5-aminopyridin-2-yl)carbamate from tert-butyl (5-nitropyridin-2-yl)carbamate: tert-butyl (5-nitropyridin-2-yl)carbamate (1 eq.), 10% palladium carbon by weight of the raw material and ethyl acetate were added to a reaction flask under hydrogen atmosphere. The reaction mixture was stirred and reacted at room temperature overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to give the target product tert-butyl (5-aminopyridin-2-yl)carbamate. The product was analyzed by HPLC-MS (Method A): retention time Rt = 1.50 min, molecular ion peak [M + H]+ m/z: 210. The reaction yield was quantitative.
References
[1] Patent: WO2016/120808, 2016, A1. Location in patent: Page/Page column 104
[2] Patent: US2010/249099, 2010, A1. Location in patent: Page/Page column 96
[3] Patent: US2011/9405, 2011, A1. Location in patent: Page/Page column 54
[4] Patent: EP2518071, 2012, A1. Location in patent: Page/Page column 41-42
[5] Patent: WO2012/146667, 2012, A1. Location in patent: Page/Page column 95-96
Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yancheng Shunde Chemical Technology Co., Ltd. | 13661532809; 13813431578 | tianleyu@163.com | China | 80 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2282 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hangzhou Milestone Pharmtech Co., Ltd. | 0571-82896630 18969958410 | sales_hz@milestonepharmtech.com | China | 4906 | 55 |
| Bellen Chemistry Co., Ltd. | 010-60400365-8001 15910885229 | service@bellenchem.com | China | 4514 | 60 |
| Candia Pharmatech Co. , Ltd. | +86-371-55216238 | China | 286 | 60 | |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
View Latest Price from Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-25 | tert-Butyl (5-aminopyridin-2-yl)carbamate
220731-04-4
|
$14.00 | 1KG | 99% | 100kg | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | tert-butyl N-(5-aminopyridin-2-yl)carbamate
220731-04-4
|
$14.00 | 1KG | 98% | 100KG | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2020-02-01 | Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
220731-04-4
|
$1.00 | 1KG | 99% | 200kgs | Career Henan Chemical Co |
-
- tert-Butyl (5-aminopyridin-2-yl)carbamate
220731-04-4
- $14.00
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- tert-butyl N-(5-aminopyridin-2-yl)carbamate
220731-04-4
- $14.00
- 98%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- Carbamic acid, (5-amino-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
220731-04-4
- $1.00
- 99%
- Career Henan Chemical Co
