4-AMINO-3-BROMO-5-NITROPYRIDINE
- CAS No.
- 89284-05-9
- Chemical Name:
- 4-AMINO-3-BROMO-5-NITROPYRIDINE
- Synonyms
- 4-AMino-3-broMo-5-nitropy...;3-bromo-5-nitro-4-pyridinamine;4-AMino-3-nitro-5-broMopyridine;4-AMINO-3-BROMO-5-NITROPYRIDINE;3-Bromo-4-amino-5-nitropyridine;4-Pyridinamine, 3-bromo-5-nitro-;4-Amino-3-bromo-5-nitropyridine 97%;4-AMINO-3-BROMO-5-NITROPYRIDINE ISO 9001:2015 REACH
- CBNumber:
- CB31076135
- Molecular Formula:
- C5H4BrN3O2
- Molecular Weight:
- 218.01
- MDL Number:
- MFCD01646057
- MOL File:
- 89284-05-9.mol
Melting point | 174-175℃ |
---|---|
Boiling point | 346.5±37.0 °C(Predicted) |
Density | 1.929 |
refractive index | 1.682 |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
form | claggy powder |
pka | 2.87±0.24(Predicted) |
color | Amber/gold |
InChI | InChI=1S/C5H4BrN3O2/c6-3-1-8-2-4(5(3)7)9(10)11/h1-2H,(H2,7,8) |
InChIKey | UXDLBXRMNSJEPB-UHFFFAOYSA-N |
SMILES | C1=NC=C([N+]([O-])=O)C(N)=C1Br |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H332-H335 |
Precautionary statements | P280-P305+P351+P338-P310 |
HS Code | 2933399990 |
4-AMINO-3-BROMO-5-NITROPYRIDINE price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A602458 | 4-Amino-3-bromo-5-nitropyridine | 89284-05-9 | 1g | $75 | 2021-12-16 | Buy |
SynQuest Laboratories | 4H55-9-02 | 4-Amino-3-bromo-5-nitropyridine | 89284-05-9 | 1g | $75 | 2021-12-16 | Buy |
AK Scientific | W9221 | 3-Bromo-5-nitropyridin-4-amine | 89284-05-9 | 5g | $78 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB139502 | 3-Bromo-5-nitropyridin-4-amine | 89284-05-9 | 5G | $110 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0037552 | 4-AMINO-3-BROMO-5-NITROPYRIDINE 95.00% | 89284-05-9 | 50MG | $117.6 | 2021-12-16 | Buy |
4-AMINO-3-BROMO-5-NITROPYRIDINE Chemical Properties,Uses,Production
Synthesis

1681-37-4

89284-05-9
The general procedure for the synthesis of 4-amino-3-bromo-5-nitropyridine from 4-amino-3-nitropyridine was as follows: 3-nitropyridin-4-amine (LXVIII) (10 g, 71.88 mmol) was mixed with acetic acid (100 ml) in a sealed tube, followed by the addition of sodium acetate (NaOAc) (29.50 g, 359 mmol), and the slow dropwise addition of bromine ( 4.43 ml, 86.3 mmol). The sealed tube was heated at 100 °C for overnight reaction under stirring conditions. Upon completion of the reaction, the mixture was concentrated under vacuum and the resulting solid was dissolved in water, alkalized with saturated aqueous sodium bicarbonate (NaHCO3) and extracted with dichloromethane (DCM). The organic phases were combined, dried and concentrated to give 3-bromo-5-nitropyridin-4-amine (LXIX) as a yellow solid (13.7 g, 62.8 mmol, 87% yield). The product was identified by 1H NMR (DMSO-d6, 500 MHz): δ 8.58 (s, 1H), 9.19 (s, 1H); ESIMS analysis showed the molecular ion peak m/z 218.1 (M + H), corresponding to the molecular formula C5H4BrN3O2.
References
[1] Patent: US2013/296302, 2013, A1. Location in patent: Paragraph 0563
[2] Patent: WO2011/84486, 2011, A1. Location in patent: Page/Page column 119-120
[3] Patent: US2013/267495, 2013, A1. Location in patent: Paragraph 0460-0461
[4] Patent: EP2464232, 2015, B1. Location in patent: Paragraph 0087; 0088
[5] Patent: US2016/68548, 2016, A1. Location in patent: Paragraph 0852
4-AMINO-3-BROMO-5-NITROPYRIDINE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3971 | 58 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 4-AMINO-3-BROMO-5-NITROPYRIDINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-01-03 | 4-Amino-3-bromo-5-nitropyridine
89284-05-9
|
US $1.00-1.00 / Kg/Drum | 1g | 98% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
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2021-09-09 | 4-AMINO-3-BROMO-5-NITROPYRIDINE
89284-05-9
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
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2019-12-23 | 4-AMINO-3-BROMO-5-NITROPYRIDINE
89284-05-9
|
US $1.00 / g | 1g | 99% | 1000KGS | Career Henan Chemical Co |
-
- 4-Amino-3-bromo-5-nitropyridine
89284-05-9
- US $1.00-1.00 / Kg/Drum
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-AMINO-3-BROMO-5-NITROPYRIDINE
89284-05-9
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 4-AMINO-3-BROMO-5-NITROPYRIDINE
89284-05-9
- US $1.00 / g
- 99%
- Career Henan Chemical Co
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