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Lisinopril Dihydrate

Lisinopril Dihydrate structure

CAS No.: 83915-83-7

Chemical Name:: Lisinopril Dihydrate

Synonyms: Lisinopril;Zestfil;renacor;isinopriL;Lisinopril API;(S) Lisinopril;L-154826：MK-521;LISINOPRIL HYDRATE;Lisinopril99%Assay;MK-521 (dihydrate)

CBNumber:: CB3113756

Molecular Formula:: C21H33N3O6

Molecular Weight:: 423.51

MDL Number:: MFCD08064198

MOL File:: 83915-83-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:56:57

Product description	Number	Pack Size	Price
Lisinopril for system suitability A European Pharmacopoeia (EP) Reference Standard	Y0001709	15 mg	$254
Lisinopril for peak identification European Pharmacopoeia (EP) Reference Standard	Y0001701	15 mg	$241
Lisinopril ≥98% (HPLC)	L6292	100mg	$442
Lisinopril dihydrate European Pharmacopoeia (EP) Reference Standard	L0702000	50 mg	$254
Lisinopril dihydrate British Pharmacopoeia (BP) Reference Standard	BP695	100MG	$287
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Lisinopril Dihydrate Properties

Melting point	148 °C
alpha	25405 -120° (c = 1 in 0.25M pH 6.4 zinc acetate); 25436 -96° (c = 1 in 0.25M pH 6.4 zinc acetate)
refractive index	-45 ° (C=1, 0.25mol/L Zinc Acetate Buffer)
storage temp.	2-8°C
solubility	H₂O: ≥10 mg/mL
form	solid
pka	2.5, 4.0, 6.7, 10.1(at 25℃)
color	white
Water Solubility	H2O: ≥10mg/mL DMSO: ~6.5mg/mL (with heating and sonicating)
Merck	14,5516
Stability	Hygroscopic
InChIKey	BAVDEDVBIHTHJQ-CFCOLZOMNA-N
SMILES	C(N1CCC[C@H]1C(=O)O)(=O)[C@H](CCCCN)N[C@H](C(=O)O)CCC1C=CC=CC=1.O \|&1:5,10,17,r\|
CAS DataBase Reference	83915-83-7(CAS DataBase Reference)
NCI Dictionary of Cancer Terms	lisinopril
FDA UNII	E7199S1YWR
NCI Drug Dictionary	lisinopril
ATC code	C09AA03
EPA Substance Registry System	L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, hydrate (1:2) (83915-83-7)
UNSPSC Code	41116107
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H360D-H373
Precautionary statements	P202-P260-P280-P308+P313-P405-P501
target organs	Kidney
PPE	Eyeshields, Gloves, type N95 (US)
Hazard Codes	Xi,Xn
Risk Statements	20/21/22
Safety Statements	22-24/25-36
WGK Germany	3
RTECS	TW3589990
HazardClass	IRRITANT
HS Code	2933995300
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Repr. 1A STOT RE 2

Lisinopril Dihydrate price More Price(75)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0001709	Lisinopril for system suitability A European Pharmacopoeia (EP) Reference Standard	83915-83-7	15 mg	$254	2026-04-30	Buy
Sigma-Aldrich	Y0001701	Lisinopril for peak identification European Pharmacopoeia (EP) Reference Standard	83915-83-7	15 mg	$241	2026-04-30	Buy
Sigma-Aldrich	L6292	Lisinopril ≥98% (HPLC)	83915-83-7	100mg	$442	2026-04-30	Buy
Sigma-Aldrich	L0702000	Lisinopril dihydrate European Pharmacopoeia (EP) Reference Standard	83915-83-7	50 mg	$254	2026-04-30	Buy
Sigma-Aldrich	BP695	Lisinopril dihydrate British Pharmacopoeia (BP) Reference Standard	83915-83-7	100MG	$287	2026-04-30	Buy

Product number	Packaging	Price	Buy
Y0001709	15 mg	$254	Buy
Y0001701	15 mg	$241	Buy
L6292	100mg	$442	Buy
L0702000	50 mg	$254	Buy
BP695	100MG	$287	Buy

Lisinopril Dihydrate Chemical Properties,Uses,Production

Description

Lisinopril is an angiotensin converting enzyme inhibitor structurally related to enalaprilat. It is reportedly useful in the management of hypertension and congestive heart failure.

Chemical Properties

White to Off-White Crystalline Powder

Originator

Merck (USA)

Uses

An orally active angiotensin-converting enzyme (ACE) inhibitor. S,S,S-Isomer of Lisinopril.

Uses

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Definition

ChEBI: Lisinopril dihydrate is a hydrate. It has a role as an antihypertensive agent. It contains a lisinopril.

brand name

Prinivil (Merck); Zestril (AstraZeneca).

General Description

Lisinopril, 1-[N²-[S-1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline dihydrate (Prinivil, Zestril), is alysine derivative of enalaprilat, the active metabolite ofenalapril. Like all ACE inhibitors, it is an active site-directedinhibitor of the enzyme, with the zinc ion used in an effectivebinding interaction at a stoichiometric ratio of 1:1. The pharmacologicaleffects of lisinopril are similar to those of captopriland enalapril.

Biochem/physiol Actions

Angiotensin converting enzyme (ACE) inhibitor.

Clinical Use

Many new ACE inhibitors became available for the treatmentof hypertension following the clinical effectivenessof enalapril. Enalapril is a non–thiol-containing ACE inhibitordevoid of the side effects of rash and loss of thesense of taste characteristic of the thiol-containing compoundcaptopril. With the exception of the phosphoruscontainingfosinopril, these antihypertensive agents havea 2-, like the prototypical drug captopril,are used in the treatment of mild-to-moderate hypertension,either alone or in conjunction with diuretics orcalcium channel blockers.

Veterinary Drugs and Treatments

The principle uses of lisinopril in veterinary medicine at present are as a vasodilator in the treatment of heart failure or hypertension. Recent studies have demonstrated that ACE inhibitors, particularly when used in conjunction with furosemide, do improve the quality of life in dogs with heart failure. It is not clear, however, whether it has any significant effect on survival times. Lisinopril may also be of benefit in treating the effects associated with valvular heart disease (mitral regurgitation) and left to right shunts. It is being explored as adjunctive treatment in chronic renal failure and in protein losing nephropathies.
Lisinopril may have advantages over other ACE inhibitors in that it may be dosed once daily and less expensive. Disadvantages are that it is only available in human labeled dosage forms and there is much less published information on its use (efficacy, safety, dosing) in veterinary species.

Lisinopril Dihydrate Preparation Products And Raw materials

Raw materials

Triethylamine hydrochloride Palladium carbon fine chemical catalyzer Polystyrene L-Lysine Trifluoroacetic acid

Triethylamine Sodium bicarbonate Benzyl chloroformate Cyclohexylurea Sodium cyanoborohydride

Magnesium sulfate Dicyclohexylcarbodiimide

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Preparation Products

Lisinopril Dihydrate Suppliers

Global( 414)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850	info@fortunachem.com	China	5994	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1006	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20121	58
Hangzhou Hyper Chemicals Limited	+86-0086-57187702781 +8613675893055	info@hyper-chem.com	China	310	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618092446649	sarah@tnjone.com	China	1143	58
Wuhan JiyunZen Tech Co., Ltd.	+86-18062099985	Amyjiyunzen@yeah.net	China	672	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58

Supplier	Advantage
Wuhan Fortuna Chemical Co., Ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hangzhou Hyper Chemicals Limited	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Wuhan JiyunZen Tech Co., Ltd.	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58

View Lastest Price from Lisinopril Dihydrate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-19	Lisinopril 83915-83-7			0.99		RongNa Biotechnology Co.,Ltd
2026-07-17	Lisinopril Dihydrate 83915-83-7		1kg	98%-102% HPLC	500KGS	WUHAN FORTUNA CHEMICAL CO., LTD
2026-07-15	Lisinopril Dihydrate 83915-83-7	$412.00	1KG	99	1T	Baoji Guokang Healthchem Co., Ltd.

Lisinopril
83915-83-7
0.99
RongNa Biotechnology Co.,Ltd

Lisinopril Dihydrate
83915-83-7
98%-102% HPLC
WUHAN FORTUNA CHEMICAL CO., LTD

Lisinopril Dihydrate
83915-83-7
$412.00
99
Baoji Guokang Healthchem Co., Ltd.

Lisinopril Dihydrate Spectrum

Lisinopril Dihydrate(83915-83-7)MS Lisinopril Dihydrate(83915-83-7)¹HNMR

83915-83-7(Lisinopril Dihydrate)Related Search:

DL-Lysine acetylsalicylate Poly(L-lysine hydrobromide) L-Lysine hydrochloride L-Lysine D-Proline

N6-TrifluoroAcetyl-L-Lysine,Lisinopril LISINOPRIL ESTER,LISINOPRIL (ETHYL) ESTER Lisinopril N∑-BENZYLOXYCARBONYL-L-LYSINYL-L-PROLINE(LISINOPRIL INTERMEDIATE) N6-TRIFLUOROACETYL-L-LYSINE /INTERMEDIATE OF LISINOPRIL

N6-Trrifluoroacetyl-L-lysine(for Lisinopril),N-6-TRIFLUORO ACETYL-L-LYSINE ( LISINOPRIL INTERMEDIATE ),N6-Trifluoroacetyl-L-lysine (for lisinopril) Lisinopril R,S,S-Diketopiperazine Pyrazine Ethylbenzene LISINOPRIL DIHYDRATE FOR PERFORMANCE TEST

FOROXYMITHINE (R) Lisinopril (S)Lisinopril-D5

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Lisinopril Related Compound A (15 mg) ((S)-2-{(3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl}-4-phenylbutanoic acid) (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate LIQUID PRED (prednisone),Lisinopril Lisinopril API Lisinopril (Zestril) Lisinopril for system suitability A Lisinopril for peak identification N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline,hydrate (1:2) Lisinopril for system suitability LISINOPRIL-D5 HYDRATE LISINOPRIL HYDRATE (ds)-1-[n2-(1-carboxy-3-phenylpropyl)-l-prolinedihydrate (s)-1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-l-prolinedihydrate (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521 L-154826：MK-521 Zestfil (S) -1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-praline dihydrate (2S)-1-[(2S)-6-Amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate (S)-(-)-1-[N-(1-Carboxy-3-phenylpropyl)-L-lysinyl]-L-proline dihydrate Lisinopril,(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521 Lisinopril (300 mg) (2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino] hexanoyl] pyrrole-2-carboxylic acid dihydrate Lisinopril 83915-83-7 LISINOPRI (DIHYDRATE) (LMK-521 (DIHYDRATE)) 1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-,dihydrate,(s)-l-prolin renacor N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide dihydrate Lisinopril dihydrate USP24,25 EP2000(III) (S) Lisinopril (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline, Dihydrate, MK-521, Acerbon, Alapril, Carace, Coric, Novatec, Prinil, Prinivil, Tensopril, Vivatec, Zestril (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid Lisinopril99%Assay LisinoprilC21H31H305*2H20 1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline (S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate LISINOPRIL DEHYDRATE (S)-1-{(S)-6-Amino-2-[((S)-1-carboxy-3-phenyl)propylamino]hexanoyl}pyrrolidine-2-carboxylic acid dihydrate (S)-Lisinopril Dihydrate LisinoprilDihydrate> Lisinopril for peak identification CRS Lisinopril dihydrate CRS Lisinopril for system suitability A CRS MK-521 (dihydrate) isinopriL LISINOPRIL DIHYDRATE Lisinopril Dihydrate USP/EP/BP Lisinopril hydrate (MK-521) Lisinopril DihydrateQ: What is Lisinopril Dihydrate Q: What is the CAS Number of Lisinopril Dihydrate Q: What is the storage condition of Lisinopril Dihydrate "Lisinopril for system suitability (Y0001235)"Q: What is "Lisinopril for system suitability (Y0001235)" Q: What is the CAS Number of "Lisinopril for system suitability (Y0001235)" Lisinopril (1368609) Lisinopril diydrate Lisinopril Dihydrate (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-proline Dihydrate Lisinopril Dihydrate, ≥ 98.0% Renopril dihydrate Lisinopril dihydrate in methanol Lisinopril dihydrate, ACE inhibitor Lisinopril dihydrate, 10 mM in DMSO LISINOPRIL DIHYDRATE USP (NON-STERILE)