7-Azabicyclo[2,2,1]heptane hydrochloride
![7-Azabicyclo[2,2,1]heptane hydrochloride Structure](CAS/GIF/27514-07-4.gif)
- CAS No.
- 27514-07-4
- Chemical Name:
- 7-Azabicyclo[2,2,1]heptane hydrochloride
- Synonyms
- 7-AZABICYCLO[2.2.1]HEPTANE HYDROCHLORIDE;SW-74;SWF-74;7-AZABICYCLO[2,2,1]HEPTANE HCL;7-Azabicyclo[2.2.1]heptane, hydrochloride (1:1);(1s,4s)-7-azabicyclo[2.2.1]heptane hydrochloride
- CBNumber:
- CB3123148
- Molecular Formula:
- C6H11N.ClH
- Molecular Weight:
- 133.62
- MDL Number:
- MFCD00154183
- MOL File:
- 27514-07-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36/37/39 |
| HS Code | 2933998090 |
7-Azabicyclo[2,2,1]heptane hydrochloride price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR962480 | 7-Azabicyclo[2.2.1]heptane hydrochloride >99% | 27514-07-4 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR962480 | 7-Azabicyclo[2.2.1]heptane hydrochloride >99% | 27514-07-4 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR962480 | 7-Azabicyclo[2.2.1]heptane hydrochloride >99% | 27514-07-4 | 1g | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR962480 | 7-Azabicyclo[2.2.1]heptane hydrochloride >99% | 27514-07-4 | 5g | $128 | 2026-06-04 | Buy |
| Apolloscientific | OR962480 | 7-Azabicyclo[2.2.1]heptane hydrochloride >99% | 27514-07-4 | 25g | $539 | 2026-06-04 | Buy |
7-Azabicyclo[2,2,1]heptane hydrochloride Chemical Properties, Uses, Production
Synthesis
![7-Azabicyclo[2.2.1]heptane, 7-[(4-methylphenyl)sulfonyl]-](/CAS/20180529/GIF/188624-92-2.gif)
188624-92-2
![7-Azabicyclo[2,2,1]heptane hydrochloride](/CAS/GIF/27514-07-4.gif)
27514-07-4
The compound (CAS: 188624-92-2, 380 g, 1.51 mol) was dissolved in tetrahydrofuran (THF, 3 L) under nitrogen protection and cooled to 0°C. Lithium aluminum hydride (229.4 g, 6.04 mol) solid pellets were added in batches over a period of 2 hours. The reaction mixture was gradually warmed to room temperature with continuous stirring for 4 days until HPLC analysis showed complete consumption of the feedstock. Upon completion of the reaction, the reaction mixture was diluted with THF (11 L) and re-cooled to 0°C. Under rapid stirring, sodium sulfate decahydrate solid was added slowly over a period of 2 h until gas release ceased. The insoluble material was removed by filtration and the filtrate was acidified with gaseous hydrogen chloride to produce a white precipitate. The precipitate was collected by filtration, washed with THF (2 x 500 mL) and dried to constant weight to give 7-azabicyclo[2,2,1]heptane hydrochloride (M1, batch 1: 86.8 g, 43%; batch 2: 97.3 g, 49%). The filter cake from the first filtration was resuspended in 6 N sodium hydroxide solution (400 mL) and filtered. The filtrate was extracted with ether (4 L) and the organic layer was acidified with gaseous hydrogen chloride, again producing a white precipitate. The precipitate was collected by filtration, washed with ether (2 x 500 mL) and dried in a vacuum oven at 40 °C to constant weight to give finally 7-azabicyclo[2,2,1]heptane hydrochloride (M I.HCl, 105.9 g, 72%).
References
[1] Patent: WO2005/79805, 2005, A1. Location in patent: Page/Page column 61
[2] Tetrahedron, 2009, vol. 65, # 29-30, p. 5805 - 5816
[3] Patent: WO2005/80402, 2005, A1. Location in patent: Page/Page column 65
[4] Organic Letters, 2001, vol. 3, # 9, p. 1371 - 1373
7-Azabicyclo[2,2,1]heptane hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing SynTitan Pharmaceutical Co., Ltd. | 025-57027686 17372956142 | li_lan@syntitan.com | China | 9999 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Shanghai Sheepchem Co., Ltd. | +86 (21) 6715-7650 | sheepchem@163.com | China | 993 | 60 |
| EnliPharma Technology Co., Ltd | 0551-66399836 18955197623 | sales@enlipharma.com | China | 1875 | 55 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
View Latest Price from 7-Azabicyclo[2,2,1]heptane hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![7-Azabicyclo[2.2.1]heptane hydrochloride pictures](/ProductImageEN1/2025-08/Small/3ead09af-0b4f-4335-8b46-db112baf044b.png) |
2026-08-25 | 7-Azabicyclo[2.2.1]heptane hydrochloride
27514-07-4
|
$2.00-6.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![7-Azabicyclo[2,2,1]heptane hydrochloride pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/5b07df1d-ea1d-4953-a01d-4257f9453292.png) |
2019-07-06 | 7-Azabicyclo[2,2,1]heptane hydrochloride
27514-07-4
|
$1.00 | 1KG | 95% | 500KG | Career Henan Chemical Co |
-
- 7-Azabicyclo[2.2.1]heptane hydrochloride
27514-07-4
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 7-Azabicyclo[2,2,1]heptane hydrochloride
27514-07-4
- $1.00
- 95%
- Career Henan Chemical Co
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