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2-(2-BROMOACETYL)THIOPHENE

CAS No.
10531-41-6
Chemical Name:
2-(2-BROMOACETYL)THIOPHENE
Synonyms
TIMTEC-BB SBB005904;2-(2-BROMOACETYL)THIOPHENE;2-(Bromoacetyl)thiophene97%;2-(Bromoacetyl)thiophene 97%;2-(2-Bromoethyl)Thiophene98%;2-(2-Bromoacetyl)thiophene97%;2-bromo-1-(2-thienyl)ethanone;2-BROMO-1-(2-THIENYL)-1-ETHANONE;Ethanone, 2-bromo-1-(2-thienyl)-;2-Bromo-1-(thien-2-yl)ethan-1-one
CBNumber:
CB7488065
Molecular Formula:
C6H5BrOS
Molecular Weight:
205.07
MDL Number:
MFCD02677721
MOL File:
10531-41-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:41

2-(2-BROMOACETYL)THIOPHENE Properties

Melting point 29-33 °C(lit.)
Boiling point 100-105°C 0,5mm
Density 1.62
Flash point >230 °F
storage temp. -20°C
form crystalline needles
color Off white/cream
Sensitive Stench
CAS DataBase Reference 10531-41-6(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H317-H319
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  C,T
Risk Statements  22-34-43
Safety Statements  26-36/37/39-45
RIDADR  UN 3261 8/PG 2
WGK Germany  3
Hazard Note  Keep Cold/Toxic/Stench
HazardClass  8
HS Code  29349990
NFPA 704
0
3 0

2-(2-BROMOACETYL)THIOPHENE price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 595594 2-(2-Bromoacetyl)thiophene 97% 10531-41-6 1g $108 2025-07-31 Buy
Sigma-Aldrich 595594 2-(2-Bromoacetyl)thiophene 97% 10531-41-6 5g $291.9 2025-07-31 Buy
TCI Chemical B5383 2-(Bromoacetyl)thiophene min. 95.0 % 10531-41-6 1G $90 2025-07-31 Buy
TCI Chemical B5383 2-(Bromoacetyl)thiophene min. 95.0 % 10531-41-6 5G $270 2025-07-31 Buy
TRC B679378 2-(2-Bromoacetyl)thiophene 10531-41-6 1g $75 2021-12-16 Buy
Product number Packaging Price Buy
595594 1g $108 Buy
595594 5g $291.9 Buy
B5383 1G $90 Buy
B5383 5G $270 Buy
B679378 1g $75 Buy

2-(2-BROMOACETYL)THIOPHENE Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Synthesis

2-Acetylthiophene

88-15-3

2-(2-BROMOACETYL)THIOPHENE

10531-41-6

Example 1.12: Synthesis of 2-bromo-1-(thiophen-2-yl)ethan-1-one. A solution of bromine (2.53 g, 0.82 mL, 0.0158 mol) in dichloromethane (8 mL) was added dropwise to a solution of 2-acetylthiophene (2.0 g, 1.71 mL, 0.0158 mol) in dichloromethane (10 mL). The reaction mixture was stirred at 25 °C for 1 h and subsequently neutralized with saturated aqueous sodium bicarbonate solution. The organic layer was washed with water and dried. After evaporation of the solvent, the solid residue was purified by column chromatography (silica gel, eluent ethyl acetate:n-hexane = 5:95) to afford 2-bromo-1-(thiophen-2-yl)ethan-1-one as an oil (2.60 g, 80% yield). [Note: Alternative preparations of 1-(thiophen-2-yl)ethan-1-one have been reported recently, see: Ostrowski, T.; Golankiewicz, B.; De Clercq, E.; Andrei, G.; Snoeck, R. Synthesis and anti-VZV activity of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues as 6-heteroaryl derivatives. eur. J. Med. Chem. 2009, 44, 3313-3317.]

References

[1] Phosphorus and Sulfur and the Related Elements, 1988, vol. 40, p. 243 - 250
[2] Synthetic Communications, 1996, vol. 26, # 6, p. 1083 - 1096
[3] Russian Journal of Organic Chemistry, 2001, vol. 37, # 9, p. 1210 - 1219
[4] ChemMedChem, 2018, vol. 13, # 11, p. 1102 - 1114
[5] Phosphorus, Sulfur and Silicon and the Related Elements, 2013, vol. 188, # 12, p. 1835 - 1844

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View Lastest Price from 2-(2-BROMOACETYL)THIOPHENE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(2-BROMOACETYL)THIOPHENE  pictures 2022-04-08 2-(2-BROMOACETYL)THIOPHENE
10531-41-6
US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
2-(2-BROMOACETYL)THIOPHENE pictures 2020-01-09 2-(2-BROMOACETYL)THIOPHENE
10531-41-6
US $9.80 / KG 1g ≥99% 100kg Career Henan Chemical Co

2-(2-BROMOACETYL)THIOPHENE Spectrum

2-Bromo-1-(2-thienyl)-1-ethanone, Tech. 2-(Bromoacetyl)thiophene 97% 2-Bromo-1-(thien-2-yl)ethan-1-one 2-broMo-1-(thiophen-2-yl)ethan-1-one 2-broMo-1-(thiophen-2-yl)-1-ethanone 2-Bromo-1-(thien-2-yl)ethan-1-one, 2-(2-Bromoethanoyl)thiophene 2-(Bromoacetyl)thiophene97% TIMTEC-BB SBB005904 2-(2-BROMOACETYL)THIOPHENE 2-BROMO-1-(2-THIENYL)-1-ETHANONE 2-(2-Bromoacetyl)thiophene97% 2-bromo-1-(2-thienyl)ethanone Ethanone, 2-bromo-1-(2-thienyl)- 2-(2-Bromoethyl)Thiophene98% Ethanone, 2-bromo-1-(2-thienyl)- (9CI) 2-(2-BROMOACETYL)THIOPHENE ISO 9001:2015 REACH 2(1H)-Pyridinone,5,6-dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-4-piperidinyl)phenyl]- 10531-41-6 Halogenated Heterocycles Heterocyclic Building Blocks Acetyl Halides Thiophenes & Benzothiophenes Halogenated Heterocycles Heterocyclic Building Blocks Thiophenes ThiophenesBuilding Blocks Acetyl Halides Thiophenes & Benzothiophenes ACETYLHALIDE Building Blocks C4 to C6 Chemical Synthesis