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2-(2-Bromoacetyl)thiophene

2-(2-Bromoacetyl)thiophene Structure
2-(2-Bromoacetyl)thiophene structure
CAS No.
10531-41-6
Chemical Name:
2-(2-Bromoacetyl)thiophene
Synonyms
2-broMo-1-(thiophen-2-yl)ethan-1-one;TIMTEC-BB SBB005904;2-(2-Bromoacetyl)thiophene;2-(Bromoacetyl)thiophene97%;2-(Bromoacetyl)thiophene 97%;2-(2-Bromoethyl)Thiophene98%;2-bromo-1-(2-thienyl)ethanone;2-(2-Bromoacetyl)thiophene97%;Ethanone, 2-bromo-1-(2-thienyl)-;2-BROMO-1-(2-THIENYL)-1-ETHANONE
CBNumber:
CB7488065
Molecular Formula:
C6H5BrOS
Molecular Weight:
205.07
MDL Number:
MFCD02677721
MOL File:
10531-41-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:59
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2-(2-Bromoacetyl)thiophene Properties

Melting point 29-33 °C(lit.)
Boiling point 100-105°C 0,5mm
Density 1.62
Flash point >230 °F
storage temp. -20°C
form crystalline needles
color Off white/cream
Sensitive Stench
InChI 1S/C6H5BrOS/c7-4-5(8)6-2-1-3-9-6/h1-3H,4H2
InChIKey UHWNENCHFSDZQP-UHFFFAOYSA-N
SMILES BrCC(=O)c1cccs1
CAS DataBase Reference 10531-41-6(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H317-H319
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  C,T
Risk Statements  22-34-43
Safety Statements  26-36/37/39-45
RIDADR  UN 3261 8/PG 2
WGK Germany  3
Hazard Note  Keep Cold/Toxic/Stench
HazardClass  8
HS Code  29349990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
0
3 0

2-(2-Bromoacetyl)thiophene price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 595594 2-(2-Bromoacetyl)thiophene 97% 10531-41-6 1g $115 2026-04-30 Buy
Sigma-Aldrich 595594 2-(2-Bromoacetyl)thiophene 97% 10531-41-6 5g $444 2026-04-30 Buy
TCI Chemical B5383 2-(Bromoacetyl)thiophene min. 95.0 % 10531-41-6 1G $82 2026-04-30 Buy
TCI Chemical B5383 2-(Bromoacetyl)thiophene min. 95.0 % 10531-41-6 5G $245 2026-04-30 Buy
Activate Scientific AS49204 2-Bromo-1-(thiophen-2-yl)ethanone 95% 10531-41-6 1g $41 2026-06-04 Buy
Product number Packaging Price Buy
595594 1g $115 Buy
595594 5g $444 Buy
B5383 1G $82 Buy
B5383 5G $245 Buy
AS49204 1g $41 Buy

2-(2-Bromoacetyl)thiophene Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powde

Synthesis

2-Acetylthiophene

88-15-3

2-(2-BROMOACETYL)THIOPHENE

10531-41-6

Example 1.12: Synthesis of 2-bromo-1-(thiophen-2-yl)ethan-1-one. A solution of bromine (2.53 g, 0.82 mL, 0.0158 mol) in dichloromethane (8 mL) was added dropwise to a solution of 2-acetylthiophene (2.0 g, 1.71 mL, 0.0158 mol) in dichloromethane (10 mL). The reaction mixture was stirred at 25 °C for 1 h and subsequently neutralized with saturated aqueous sodium bicarbonate solution. The organic layer was washed with water and dried. After evaporation of the solvent, the solid residue was purified by column chromatography (silica gel, eluent ethyl acetate:n-hexane = 5:95) to afford 2-bromo-1-(thiophen-2-yl)ethan-1-one as an oil (2.60 g, 80% yield). [Note: Alternative preparations of 1-(thiophen-2-yl)ethan-1-one have been reported recently, see: Ostrowski, T.; Golankiewicz, B.; De Clercq, E.; Andrei, G.; Snoeck, R. Synthesis and anti-VZV activity of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues as 6-heteroaryl derivatives. eur. J. Med. Chem. 2009, 44, 3313-3317.]

References

[1] Phosphorus and Sulfur and the Related Elements, 1988, vol. 40, p. 243 - 250
[2] Synthetic Communications, 1996, vol. 26, # 6, p. 1083 - 1096
[3] Russian Journal of Organic Chemistry, 2001, vol. 37, # 9, p. 1210 - 1219
[4] ChemMedChem, 2018, vol. 13, # 11, p. 1102 - 1114
[5] Phosphorus, Sulfur and Silicon and the Related Elements, 2013, vol. 188, # 12, p. 1835 - 1844

2-(2-Bromoacetyl)thiophene Preparation Products And Raw materials

Raw materials

2-Acetylthiophene Carbon tetrachloride Bromine Iron Dichloromethane
Sodium bicarbonate

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Preparation Products

2-Thiophen-2-yl-indolizine 2-Hydrazino-4-(2-thienyl)thiazole, 97% 2-Methyl-4-(2-thienyl)-1,3-thiazole 2-(5-Bromo-2-thienyl)quinoline 2-Thiophen-2-yl-imidazo[1,2-a]pyridine

2-(2-Bromoacetyl)thiophene Suppliers

Global Suppliers ( 147)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Amber MolTech LLC 086-010-62176588 amber@jyamber.com China 10150 56
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2297 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Energy Chemical 61
Capot Chemical Co., Ltd 66
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
Amber MolTech LLC 56
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 55

View Latest Price from 2-(2-Bromoacetyl)thiophene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(2-BROMOACETYL)THIOPHENE pictures 2026-08-20 2-(2-BROMOACETYL)THIOPHENE
10531-41-6
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
2-(2-BROMOACETYL)THIOPHENE pictures 2020-01-09 2-(2-BROMOACETYL)THIOPHENE
10531-41-6
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

2-(2-Bromoacetyl)thiophene Spectrum

2-(2-BROMOACETYL)THIOPHENE(10531-41-6)1HNMR

10531-41-6 (2-(2-Bromoacetyl)thiophene) Related Search:

2-Bromo-1-(5-chloro-3-methylbenzo[b]thiophen-2-yl)ethan-1-one 5-(bromoacetyl)thiophene-2-carbonitrile,5-(2-Bromoacetyl)thiophene-2-carbonitrile 2-(2-Bromoacetyl)thiophene 2-Bromo-1-(5-phenyl-2-thienyl)-1-ethanone 2-Bromo-1-(5-bromothiophen-2-yl)ethanone
2-Bromo-1-[5-(2-pyridinyl)-2-thienyl]-1-ethanone 1-(1-Benzothiophen-2-yl)-2-bromo-1-ethanone 2-Bromo-1-(3,5-dimethyl-1-benzothiophen-2-yl)-1-ethanone 2-Bromo-1-(5-chloro-thiophen-2-yl)-ethanone 2-Bromo-1-(5-chloro-3-methylbenzo[b]thiophen-2-yl)ethan-1-one
5-(Bromoacetyl)thiophene-2-carboxamide 2-Bromo-1-(3-bromo-2-thienyl)-1-ethanone 2-Bromo-1-(2-thienyl)-1-propanone 2-Bromo-1-(3-chloro-2-thienyl)-1-ethanone 3-Bromo-4-oxo-4-thien-2-ylbutanoic acid
2,2-Dibromo-1-(5-bromo-2-thienyl)ethan-1-one N-(5-Bromo-6-oxo-5,6-dihydro-4H-cyclopenta[b]thiophen-4-yl)-2,2,2-trifluoroacetamide 2,2-Dibromo-1-thien-2-ylethanone

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2-Bromo-1-(2-thienyl)-1-ethanone, Tech. 2-(Bromoacetyl)thiophene 97% 2-Bromo-1-(thien-2-yl)ethan-1-one 2-broMo-1-(thiophen-2-yl)-1-ethanone 2-Bromo-1-(thien-2-yl)ethan-1-one, 2-(2-Bromoethanoyl)thiophene 2-(Bromoacetyl)thiophene97% TIMTEC-BB SBB005904 2-BROMO-1-(2-THIENYL)-1-ETHANONE 2-(2-Bromoacetyl)thiophene97% 2-bromo-1-(2-thienyl)ethanone Ethanone, 2-bromo-1-(2-thienyl)- 2-(2-Bromoethyl)Thiophene98% Ethanone, 2-bromo-1-(2-thienyl)- (9CI) 2-(2-BROMOACETYL)THIOPHENE ISO 9001：2015 REACH 2(1H)-Pyridinone,5,6-dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-4-piperidinyl)phenyl]- 2-broMo-1-(thiophen-2-yl)ethan-1-one 2-(2-Bromoacetyl)thiophene 10531-41-6 Halogenated Heterocycles Heterocyclic Building Blocks Acetyl Halides Thiophenes & Benzothiophenes Halogenated Heterocycles Heterocyclic Building Blocks Thiophenes ThiophenesBuilding Blocks Acetyl Halides Thiophenes & Benzothiophenes ACETYLHALIDE Building Blocks C4 to C6 Chemical Synthesis