2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE
- CAS No.
- 95453-58-0
- Chemical Name:
- 2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE
- Synonyms
- 2-chlorothiazole-5-carbaldehyde;2-Chloro-5-formylthiazole;2-Chloro-5-formyl-1,3-thiazole;2-Chloro-5-thiazolecarbaldehyde;2-chloro-5-thiazolecarboxaldehyde;2-Chlorothiazole-5-carboxaldehyde;5-Thiazolecarboxaldehyde, 2-chloro-;2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE;2-Chloro-1,3-thiazole-5-carboxaldehyde;5-Thiazolecarboxaldehyde, 2-chloro- (9CI)
- CBNumber:
- CB3138166
- Molecular Formula:
- C4H2ClNOS
- Molecular Weight:
- 147.58
- MDL Number:
- MFCD01568717
- MOL File:
- 95453-58-0.mol
- MSDS File:
- SDS
| Melting point | 85-88°C |
|---|---|
| Boiling point | 278.6±32.0 °C(Predicted) |
| Density | 1.541±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -0.94±0.10(Predicted) |
| form | Solid |
| color | White to orange |
| Sensitive | Air Sensitive |
| InChI | InChI=1S/C4H2ClNOS/c5-4-6-1-3(2-7)8-4/h1-2H |
| InChIKey | PKCBQQXHFIDIIG-UHFFFAOYSA-N |
| SMILES | S1C(C=O)=CN=C1Cl |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317 | |||||||||
| Precautionary statements | P261-P264-P270-P280-P301+P312-P302+P352 | |||||||||
| Risk Statements | 43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2934100090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SYX00395 | 2-Chlorothiazole-5-carboxaldehyde | 95453-58-0 | 1g | $379 | 2026-04-30 | Buy |
| Apolloscientific | OR14891 | 2-Chloro-1,3-thiazole-5-carboxaldehyde 98% | 95453-58-0 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR14891 | 2-Chloro-1,3-thiazole-5-carboxaldehyde 98% | 95453-58-0 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR14891 | 2-Chloro-1,3-thiazole-5-carboxaldehyde 98% | 95453-58-0 | 5g | $67 | 2026-06-04 | Buy |
| Activate Scientific | AS1850 | 2-Chlorothiazole-5-carbaldehyde 98% | 95453-58-0 | 1g | $27 | 2026-06-04 | Buy |
2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE Chemical Properties,Uses,Production
Synthesis
3034-52-4
109-94-4
95453-58-0
General procedure: n-Butyl lithium (n-BuLi, 320 mL, 0.8 mol) was slowly added dropwise to a stirred solution of anhydrous THF (1000 mL) of 2-chlorothiazole (80 g) at -78 °C for 1 hour. Maintaining the reaction temperature at -78 °C, ethyl formate (74 g) was slowly added dropwise to the above solution, and the reaction continued to be stirred for 1 hour after the dropwise addition was completed. Saturated ammonium chloride (NH4Cl) solution was added to the reaction mixture and stirred for 30 minutes. Subsequently, the reaction mixture was diluted with ethyl acetate. The aqueous phase was separated and extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated brine and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure to give the crude product. The crude product was purified by recrystallization from hexane/ethyl acetate mixed solvent to give 2-chloro-1,3-thiazole-5-carbaldehyde (72 g, yield: 73%). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 9.96 (s, 1H), 8.21 (s, 1H).
References
[1] Patent: WO2016/55431, 2016, A1. Location in patent: Page/Page column 75
2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Yutebang New Material Technology Co., Ltd. | 029-84536388 19991842844 | ella@yutbon.com | China | 155 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1399 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Lastest Price from 2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 2-Chloro-1,3-thiazole-5-carbaldehyde
95453-58-0
|
$1.60-6.60 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-04-04 | 2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE
95453-58-0
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd.
|
||
 |
2020-01-13 | 2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE
95453-58-0
|
$1.00 | 1g | 98% | 100KG | Career Henan Chemical Co |
-
- 2-Chloro-1,3-thiazole-5-carbaldehyde
95453-58-0
- $1.60-6.60
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE
95453-58-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE
95453-58-0
- $1.00
- 98%
- Career Henan Chemical Co
95453-58-0(2-CHLORO-1,3-THIAZOLE-5-CARBALDEHYDE)Related Search:
1of4
