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ChemicalBook >> CAS DataBase List >>(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Structure
(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride structure
CAS No.
125572-93-2
Chemical Name:
(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride
Synonyms
rotigotine HCl;Rotigotine hydrochloride;(6S)-;CS-1395;Rotigotina HCl;Rotigotine hydrochlo;Abametapir Impurity 22;hydrochloride hcl powder;Rotocontine hydrochloride;CEXBONHIOKGWNU-NUDVEOEASA-N
CBNumber:
CB31457147
Molecular Formula:
C19H26ClNOS
Molecular Weight:
351.93
MDL Number:
MFCD00906149
MOL File:
125572-93-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Properties

Melting point 114-117°C
Density 1.2g/cm3 at 20℃
vapor pressure 0-0Pa at 20-25℃
storage temp. room temp
solubility Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form solid
color white to off-white
Stability Hygroscopic
InChI 1S/C19H25NOS.ClH/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21;/h3-7,13,16,21H,2,8-12,14H2,1H3;1H/t16-;/m0./s1
InChIKey CEXBONHIOKGWNU-NTISSMGPSA-N
SMILES Cl.CCCN(CCc1cccs1)[C@H]2CCc3c(O)cccc3C2
LogP 3.1 at 20℃ and pH7
Surface tension 72.3mN/m at 1g/L and 20℃
FDA UNII 6Q1W9573L2
UNSPSC Code 41116107
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H412-H317-H302
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P273-P501
WGK Germany  2
HS Code  2934990002
Storage Class 11 - Combustible Solids
REACH Registrations Active

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R9281 Rotigotine hydrochloride ≥98% (HPLC) 125572-93-2 5MG $115 2026-04-30 Buy
Sigma-Aldrich Y0002005 Rotigotine hydrochloride European Pharmacopoeia (EP) Reference Standard 125572-93-2 70 mg $196 2026-04-30 Buy
Sigma-Aldrich R9281 Rotigotine hydrochloride ≥98% (HPLC) 125572-93-2 25MG $444 2026-04-30 Buy
Usbiological 256502 Rotigotine hydrochloride Asreported 125572-93-2 10mg $380 2026-06-03 Buy
Usbiological 256502 Rotigotine hydrochloride Asreported 125572-93-2 50mg $891 2026-06-03 Buy
Product number Packaging Price Buy
R9281 5MG $115 Buy
Y0002005 70 mg $196 Buy
R9281 25MG $444 Buy
256502 10mg $380 Buy
256502 50mg $891 Buy

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Chemical Properties, Uses, Production

Chemical Properties

White to Off-White Solid

Uses

It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.

Biochem/physiol Actions

Rotigotine is a dopamine receptor agonist with preference for D3 receptors over D2 and D1. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D2 agonist.

in vivo

In primed rats, Rotigotine (N-0923) (0.035, 0.1 and 0.35 mg/kg) induces contralateral turning behavior in a dose dependent manner. In drug naive rats, the turning behavior induced by Rotigotine, either alone or in combination with SCH 39166, is reduced compared to primed rats[3].

IC 50

D3 Receptor: 0.71 nM (Ki); D2 Receptor: 4-15 nM (Ki); D5 Receptor: 4-15 nM (Ki); D4 Receptor: 4-15 nM (Ki); D1 Receptor: 83 nM (Ki); α1A: 176 nM (Ki); α1B: 273 nM (Ki); α2A: 338 nM (Ki); α2B: 27 nM (Ki); 5-HT1A Receptor: 30 nM (Ki); 5-HT7 Receptor: 86 nM (Ki)

storage

room temperature (desiccate)

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Suppliers

Global Suppliers ( 186)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6744 52
Shanghai Feibo Chemical Technology Co., Ltd 021-58955608,2250286 15921236618 blinkzeng@gmail.com China 522 62
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chembest Research Laboratories Limited 61
Capot Chemical Co., Ltd 66
Pure Chemistry Scientific Inc. 62
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
XiaoGan ShenYuan ChemPharm co,ltd 52
Shanghai Feibo Chemical Technology Co., Ltd 62

View Latest Price from (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rotigotine Hydrochloride pictures 2026-07-27 Rotigotine Hydrochloride
125572-93-2
 $37.00-88.00 99.66% 10g TargetMol Chemicals Inc.
hydrochloride hcl powder pictures 2020-09-25 hydrochloride hcl powder
125572-93-2
 $15.00 1KG 99% 500 Ton/Tons per Month Hebei Runbin Biotechnology Co. LTD
hydrochloride hcl powder pictures 2020-09-25 hydrochloride hcl powder
125572-93-2
 $15.00 1KG 99% 500 Ton/Tons per Month Hebei Runbin Biotechnology Co. LTD

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Spectrum

(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride(125572-93-2)1HNMR

125572-93-2 ((6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride) Related Search:

2-Naphthalenamine, 1,2,3,4-tetrahydro-N-methyl-N-propyl-, hydrochloride Methyl-(2-thiophen-2-yl-ethyl)-amine hydrochloride 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]- (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Thiophene-2-ethylamine
ROTIGOTINE

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(6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenolhydrochloride (S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (6S)- 8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]- CEXBONHIOKGWNU-NUDVEOEASA-N (S)-6-(propyl(2-(thiophen-2-yl)ethyl)aMino)-5,6,7,8-tetrahydronaphthalen-1-ol 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-, hydrochloride, (6S)- (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride 1-Naphthalenol,5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]aMino]-, hydrochloride (1:1),(6S)- CS-1395 [2H3]-Rac Rotigotine Hydrochloride Salt hydrochloride hcl powder Rotigotine hydrochlo (6S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hyd... Rotigotina HCl Rotigotine hydrochloride salt (S)-6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol hydrochloride Abametapir Impurity 22 Rotigotine hydrochloride, Dopamine receptor agonist (6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1) Rotigotine Hydrochloride, 10 mM in DMSO Rotocontine hydrochloride Rotigotine hydrochloride (Rotigotine HCl) Rotigotine hydrochloride rotigotine HCl 125572-93-2 C19H25NOSHCl C19H26ClNOS APIs Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds API