Thiophene-2-ethylamine
- CAS No.
- 30433-91-1
- Chemical Name:
- Thiophene-2-ethylamine
- Synonyms
- 2-(thiophen-2-yl)ethan-1-aMine;2-THIOPHENEETHYLAMINE;2-(2-AMINOETHYL)THIOPHENE;Thiophen-2-ylacetyl chloride;2-Thien-2-yL;ThiopheneEthaMine;RARECHEM AL BW 0099;2-Thiopheneethamine;2-Thiopheneethylamin;2-ThiophenethylaMine
- CBNumber:
- CB4853460
- Molecular Formula:
- C6H9NS
- Molecular Weight:
- 127.21
- MDL Number:
- MFCD06090846
- MOL File:
- 30433-91-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 202 °C |
|---|---|
| Boiling point | 200-201 °C/750 mmHg (lit.) |
| Density | 1.087 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 190 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol |
| pka | 9.47±0.10(Predicted) |
| form | Liquid |
| Specific Gravity | 1.087 |
| color | Colorless to yellow |
| Sensitive | Air Sensitive |
| BRN | 106962 |
| InChI | 1S/C6H9NS/c7-4-3-6-2-1-5-8-6/h1-2,5H,3-4,7H2 |
| InChIKey | HVLUYXIJZLDNIS-UHFFFAOYSA-N |
| SMILES | NCCc1cccs1 |
| CAS DataBase Reference | 30433-91-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Thiophene-2-ethylamine price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 423270 | 2-Thiopheneethylamine 96% | 30433-91-1 | 1g | $32.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 423270 | 2-Thiopheneethylamine 96% | 30433-91-1 | 5g | $163 | 2026-04-30 | Buy |
| TCI Chemical | A1637 | 2-(2-Aminoethyl)thiophene >98.0%(GC) | 30433-91-1 | 25g | $84 | 2026-04-30 | Buy |
| TCI Chemical | A1637 | 2-(2-Aminoethyl)thiophene >98.0%(GC) | 30433-91-1 | 250g | $528 | 2026-04-30 | Buy |
| TRC | TRC-T368160-5G | [2-(Thiophene-2-yl)ethyl]amine | 30433-91-1 | 5g | $165 | 2026-06-03 | Buy |
Thiophene-2-ethylamine Chemical Properties,Uses,Production
Chemical Properties
A colorless to yellow liquid with unstable properties requiring protection with nitrogen gas. It appears as a light yellow clear liquid, but turns red upon prolonged exposure.
Uses
[2-(Thiophene-2-yl)ethyl]amine is used in the synthesis of geldanamycin derivatives as HCV replication inhibitors targetting Hsp90.
Uses
2-Thiopheneethylamine (2-thiophene ethyl amine, 2-(thien-2-yl)ethylamine) is suitable to functionalize multiwall carbon nanotubes (MWCNT).
It may be used as a reactant in the synthesis of pyrimidine derivatives by reacting with various isothiocyanatoketones and acylguanidines derivatives by reacting with aroyl S-methylisothiourea.
General Description
2-Thiopheneethylamine (2-(thiophen-2-yl)ethanamine) is an aromatic amine. It undergoes microwave induced condensation with iminodiacetic acid to form the corresponding piperazine-2,6-dione derivatives. Its effect as a probable substitute to the pyridine ligand on the performance of poly(3-hexylthiophene)/CdSe hybrid solar cells has been investigated.
Synthesis
N,N-Dimethylformamide (DMF) reacts with thiophene to obtain 2-thiophenecarbaldehyde, then reacts with isopropyl chloroacetate to obtain 2-thiopheneacetaldehyde, and then reacts with hydroxylamine hydrochloride to obtain 2-thiopheneacetaldehyde oxime, and finally reduced to give 2-thiopheneethylamine.
References
[1] M. BARWIOLEK. Structural and spectral studies of silver(I) complexes with new Schiff bases derived from 2-thiopheneethylamine and their application in thin layer deposition by spin and dip coating techniques[J]. Polyhedron, 2017, 124: Pages 12-21. DOI:10.1016/j.poly.2016.12.011.
[2] BHUSHAN D. VARPE S B J. Schiff Base of Isatin with 2-Thiopheneethylamine and Its Mannich Bases: Synthesis, Docking, and In Vitro Anti-Inflammatory and Antitubercular Activity[J]. Russian Journal of Bioorganic Chemistry, 2022, 48 2: 372-379. DOI:10.1134/S1068162022020030.
[3] JUN YAN LEK. Understanding the Effect of Surface Chemistry on Charge Generation and Transport in Poly (3-hexylthiophene)/CdSe Hybrid Solar Cells[J]. ACS Applied Materials & Interfaces, 2011, 3 2: 287-292. DOI:10.1021/am100938f.
[4] SANDEEP KUMAR. Efficient synthesis of piperazine-2,6-dione and 4-(1H-indole-2-carbonyl)piperazine-2,6-dione derivatives and their evaluation for anticancer activity[J]. Medicinal Chemistry Research, 2013, 22 10: 4600-4609. DOI:10.1007/s00044-012-0438-7.
Thiophene-2-ethylamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
View Lastest Price from Thiophene-2-ethylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Thiophene-2-ethylamine
30433-91-1
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-06-30 | Thiophene-2-ethylamine
30433-91-1
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-06-20 | 2-Thiopheneethylamine
30433-91-1
|
1kg | 99% | 20tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Thiophene-2-ethylamine
30433-91-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Thiophene-2-ethylamine
30433-91-1
- 98
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-Thiopheneethylamine
30433-91-1
- $0.00
- 99%
- Hebei Yanxi Chemical Co., Ltd.
