ChemicalBook >> CAS DataBase List >>1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-

1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-

CAS No.
2413068-25-2
Chemical Name:
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-
Synonyms
(7S)-BAY-593;1-Propanone,3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-;1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-
CBNumber:
CB314686017
Molecular Formula:
C26H31F3N2O3
Molecular Weight:
476.53
MDL Number:
MOL File:
2413068-25-2.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:03

1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Properties

Boiling point 575.1±50.0 °C(predicted)
Density 1.25±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 10.49±0.40(predicted)
form Solid
color White to off-white

1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1176085 (7S)-BAY-593 99.61% 2413068-25-2 5mg $596 2026-06-04 Buy
ChemScene CS-1176085 (7S)-BAY-593 99.61% 2413068-25-2 10mg $953 2026-06-04 Buy
ChemScene CS-1176085 (7S)-BAY-593 99.61% 2413068-25-2 25mg $1907 2026-06-04 Buy
ChemScene CS-1176085 (7S)-BAY-593 99.61% 2413068-25-2 50mg $3033 2026-06-04 Buy
ChemScene CS-1176085 (7S)-BAY-593 99.61% 2413068-25-2 100mg $4821 2026-06-04 Buy
Product number Packaging Price Buy
CS-1176085 5mg $596 Buy
CS-1176085 10mg $953 Buy
CS-1176085 25mg $1907 Buy
CS-1176085 50mg $3033 Buy
CS-1176085 100mg $4821 Buy

1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Chemical Properties, Uses, Production

Uses

(7S)-BAY-593 is the S-enantiomer of BAY-593 (HY-161573). BAY-593 is an orally active GGTase-I inhibitor. BAY-593 can block YAP1/TAZ signaling in animals and has antitumor activity[1].

IC 50

YAP/TAZ-TEAD; GGTase I

References

[1] Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456(24)00087-4. DOI:10.1016/j.chembiol.2024.02.013

1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Preparation Products And Raw materials

Raw materials

Preparation Products

1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai meikai technology co., ltd 021-68689288 15300790979 info@mkbio.com.cn China 9988 58
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- (7S)-BAY-593 1-Propanone,3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl- 2413068-25-2