1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-
- CAS No.
- 2413068-25-2
- Chemical Name:
- 1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-
- Synonyms
- (7S)-BAY-593;1-Propanone,3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-;1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-
- CBNumber:
- CB314686017
- Molecular Formula:
- C26H31F3N2O3
- Molecular Weight:
- 476.53
- MDL Number:
- MOL File:
- 2413068-25-2.mol
- MSDS File:
- SDS
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1176085 | (7S)-BAY-593 99.61% | 2413068-25-2 | 5mg | $596 | 2026-06-04 | Buy |
| ChemScene | CS-1176085 | (7S)-BAY-593 99.61% | 2413068-25-2 | 10mg | $953 | 2026-06-04 | Buy |
| ChemScene | CS-1176085 | (7S)-BAY-593 99.61% | 2413068-25-2 | 25mg | $1907 | 2026-06-04 | Buy |
| ChemScene | CS-1176085 | (7S)-BAY-593 99.61% | 2413068-25-2 | 50mg | $3033 | 2026-06-04 | Buy |
| ChemScene | CS-1176085 | (7S)-BAY-593 99.61% | 2413068-25-2 | 100mg | $4821 | 2026-06-04 | Buy |
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Chemical Properties, Uses, Production
Uses
(7S)-BAY-593 is the S-enantiomer of BAY-593 (HY-161573). BAY-593 is an orally active GGTase-I inhibitor. BAY-593 can block YAP1/TAZ signaling in animals and has antitumor activity[1].
IC 50
YAP/TAZ-TEAD; GGTase I
References
[1] Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456(24)00087-4. DOI:10.1016/j.chembiol.2024.02.013
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Preparation Products And Raw materials
Raw materials
Preparation Products
1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 9988 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Shanghai meikai technology co., ltd | 58 |
2413068-25-2 (1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7S)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)-) Related Search:
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