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PROTAC PIN1 degrader-1

PROTAC PIN1 degrader-1 Structure
PROTAC PIN1 degrader-1 structure
CAS No.
3038591-59-9
Chemical Name:
PROTAC PIN1 degrader-1
Synonyms
PROTAC PIN1 degrader-1
CBNumber:
CB314907855
Molecular Formula:
C51H52N10O7
Molecular Weight:
917.02
MDL Number:
MOL File:
3038591-59-9.mol
Last updated:2025-04-18 09:52:03
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PROTAC PIN1 degrader-1 Properties

Density 1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 10.70±0.40(predicted)

PROTAC PIN1 degrader-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1224465 PROTAC PIN1 degrader-1 97.39% 3038591-59-9 1mg $433 2026-06-04 Buy
ChemScene CS-1224465 PROTAC PIN1 degrader-1 97.39% 3038591-59-9 5mg $1083 2026-06-04 Buy
ChemScene CS-1224465 PROTAC PIN1 degrader-1 97.39% 3038591-59-9 10mg $1733 2026-06-04 Buy
ChemScene CS-1224465 PROTAC PIN1 degrader-1 97.39% 3038591-59-9 25mg $3250 2026-06-04 Buy
ChemScene CS-1224465 PROTAC PIN1 degrader-1 97.39% 3038591-59-9 50mg $5254 2026-06-04 Buy
Product number Packaging Price Buy
CS-1224465 1mg $433 Buy
CS-1224465 5mg $1083 Buy
CS-1224465 10mg $1733 Buy
CS-1224465 25mg $3250 Buy
CS-1224465 50mg $5254 Buy

PROTAC PIN1 degrader-1 Chemical Properties, Uses, Production

Uses

PROTAC PIN1 degrader-1 (compound D4) is a PROTAC targeting PIN1, with a DC50=1.8 nM. The GI50 of PROTAC PIN1 degrader-1 to MDA-MB-468 is >30 μM. PROTAC PIN1 degrader-1 is composed of target protein ligand PIN1 ligand-1 (HY-168038) (red part), E3 ligase ligand Thalidomide (HY-14658) (blue part), and PROTAC linker (black part)[1].

References

[1] Liu C, et al. Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs. J Med Chem. 2024 Sep 12;67(17):15780-15795. DOI:10.1021/acs.jmedchem.4c01412

PROTAC PIN1 degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC PIN1 degrader-1 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58

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PROTAC PIN1 degrader-1 3038591-59-9