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Betaxolol hydrochloride

CAS No.
63659-19-8
Chemical Name:
Betaxolol hydrochloride
Synonyms
SL 75212;BETAXOLOL HCL;Kerlon;kerlone;betoptic;sl-d.212;Betaxolo;Betoptima;sl75212-10;SL 75212 HCl
CBNumber:
CB3153329
Molecular Formula:
C18H30ClNO3
Molecular Weight:
343.89
MDL Number:
MFCD00242959
MOL File:
63659-19-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
Product description Number Pack Size Price
Betaxolol for peak identification European Pharmacopoeia (EP) Reference Standard Y0001360 15 mg $127
Betaxolol hydrochloride >98% (HPLC) B5683 10mg $210
Betaxolol hydrochloride British Pharmacopoeia (BP) Reference Standard BP686 100 mg $251
Betaxolol hydrochloride European Pharmacopoeia (EP) Reference Standard B1103000 60 mg $164
Betaxolol hydrochloride United States Pharmacopeia (USP) Reference Standard 1069903 200mg $455
More product size

Betaxolol hydrochloride Properties

Melting point 116°
storage temp. 2-8°C
solubility H2O: 36 mg/mL, soluble
form solid
color white
Water Solubility Soluble to 50 mM in water
Merck 14,1182
Stability Hygroscopic
Major Application pharmaceutical (small molecule)
InChI InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChIKey CHDPSNLJFOQTRK-UHFFFAOYSA-N
SMILES C1(OCC(O)CNC(C)C)C=CC(CCOCC2CC2)=CC=1.Cl
CAS DataBase Reference 63659-19-8(CAS DataBase Reference)
FDA UNII 6X97D2XT0O
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  UA9823000
HS Code  2922504500
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Toxicity LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury)
NFPA 704
0
1 0

Betaxolol hydrochloride price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001360 Betaxolol for peak identification European Pharmacopoeia (EP) Reference Standard 63659-19-8 15 mg $127 2026-04-30 Buy
Sigma-Aldrich B5683 Betaxolol hydrochloride >98% (HPLC) 63659-19-8 10mg $210 2026-04-30 Buy
Sigma-Aldrich BP686 Betaxolol hydrochloride British Pharmacopoeia (BP) Reference Standard 63659-19-8 100 mg $251 2026-04-30 Buy
Sigma-Aldrich B1103000 Betaxolol hydrochloride European Pharmacopoeia (EP) Reference Standard 63659-19-8 60 mg $164 2026-04-30 Buy
Sigma-Aldrich 1069903 Betaxolol hydrochloride United States Pharmacopeia (USP) Reference Standard 63659-19-8 200mg $455 2026-04-30 Buy
Product number Packaging Price Buy
Y0001360 15 mg $127 Buy
B5683 10mg $210 Buy
BP686 100 mg $251 Buy
B1103000 60 mg $164 Buy
1069903 200mg $455 Buy

Betaxolol hydrochloride Chemical Properties,Uses,Production

Description

Betaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β1-adrenergic receptor antagonist. Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .

Description

Betaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid of intrinsic sympathomimetic and membrane stabilizing properties. Its long duration of action permits once-daily dosing in mild to moderate hypertension. It is also being evaluated in glaucoma.

Chemical Properties

White or almost white, crystalline powder.

Originator

Synthelabo (France)

Uses

antifungal

Uses

Betaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.

Definition

ChEBI: The hydrochloride salt of betaxolol.

brand name

Betoptic (Alcon); Kerlone (Sanofi Aventis).

Biological Activity

Selective β 1 -adrenoceptor antagonist.

storage

Store at RT

References

[1] SEUNG-WOON MYUNG  Cheon H J. Gas chromatograph–mass spectrometric method for the determination of carvedilol and its metabolites in human urine[J]. Journal of Chromatography B, 2005, 822 1: Pages 70-77. DOI: 10.1016/j.jchromb.2005.05.023
[2] PANKAJ GUPTA R G. Amino Functionalized Graphene Oxide and Polymer Nanocomposite Based Electrochemical Platform for Sensitive Assay of Anti-Doping Drug Atenolol in Biological Fluids[J]. Journal of The Electrochemical Society, 2016, 163 1. DOI: 10.1149/2.0281613jes
[3] A WELLSTEIN  G G B  D Palm. Affinity and selectivity of beta-adrenoceptor antagonists in vitro.[J]. Journal of Cardiovascular Pharmacology, 1986, 8 Suppl 11: S36-40. DOI: 10.1097/00005344-198511001-00006
[4] DOROTA POZAROWSKA  Zbigniew D  Piotr Pozarowski. Cytometric assessment of cytostatic and cytotoxic effects of topical glaucoma medications on human epithelial corneal line cells[J]. Cytometry Part B: Clinical Cytometry, 2009, 78B 2: 130-137. DOI: 10.1002/cyto.b.20493
[5] N. SHARIF. Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes.[J]. Journal of Ocular Pharmacology and Therapeutics, 2001, 26 1: 305-317. DOI: 10.1089/108076801753162726
[6] GLYN CHIDLOW  Neville N O  José Melena. Betaxolol, a β1-adrenoceptor antagonist, reduces Na+ influx into cortical synaptosomes by direct interaction with Na+ channels: comparison with other β-adrenoceptor antagonists[J]. British Journal of Pharmacology, 2009, 130 4: 759-766. DOI: 10.1038/sj.bjp.0703369

Betaxolol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 279)Suppliers
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Henan Tianfu Chemical Co.,Ltd.
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View Lastest Price from Betaxolol hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Betaxolol hydrochloride pictures 2026-08-13 Betaxolol hydrochloride
63659-19-8
1KG 99%min 500KGS WUHAN FORTUNA CHEMICAL CO., LTD
Betaxolol hydrochloride pictures 2026-07-15 Betaxolol hydrochloride
63659-19-8
$32.00-77.00 99.48% 10g TargetMol Chemicals Inc.
Betaxolol hydrochloride pictures 2026-07-15 Betaxolol hydrochloride
63659-19-8
$32.00-77.00 99.48% 10g TargetMol Chemicals Inc.

Betaxolol hydrochloride Spectrum

1-[4-[2-(CYCLOPROPYLMETHOXY)ETHYL]PHENOXY]-3-ISOPROPYLAMINO-2-PROPANOL HYDROCHLORIDE BETAXOLOL CHLOROHYDRATE BETAXOLOL HYDROCHLORIDE BETAXOLOL HYDROCHLORIDE MONOHYDRATE (+-)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propano 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-isopropylaminopropan-2-olhydroc Betaxolol for peak identification BETAXALOL HYDROCHLORIDE 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol,hydrochloride (1:1) SL 75212 HCl 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)-2-propanol hydrate hydrochloride betoptic kerlone sl75212-10 sl-d.212 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]propan-2-ol hydrochloride Betaxolo 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride Betoptima (R)-Betaxolol-d7 Hydrochloride βxolol hydrochloride (±)-Betaxolol-d7 HCl 1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol hydrochloride Kerlon Betaxolol Hydrochloride (200 mg) Betaxolol hydrochloride CRS Betaxolol for peak identification CRS Betaxolol hydrochloride USP/EP/BP Betaxolol hydrochloride salt Betaxolol hydrochlor Betaxolol HCl (SL75212) 1-(isopropylamino)-3-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy... Betaxolol HClQ: What is Betaxolol HCl Q: What is the CAS Number of Betaxolol HCl Q: What is the storage condition of Betaxolol HCl Q: What are the applications of Betaxolol HCl Betaxolol Hydrochloride (1069903) Betaxolol HC Betaprolol hydrochloride Betaxolol Hydrochloride EP Impurity E as Hydrochloride Betaxolol hydrochloride, 10 mM in DMSO Betaxolol HCl - Bio-X ? Betaxolol hydrochloride 98~102% 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)propan-2-ol hydrochloride BETAXOLOL HCL SL 75212 63659-19-8 633659-19-8 63959-19-8 C18H29NO3HClH2O C18H29NO3HCl Cardiovascular Adrenoceptor