SDZ 220-581
- CAS No.
- 174575-17-8
- Chemical Name:
- SDZ 220-581
- Synonyms
- SDZ 220-581;SDZ 220581,SDZ 220 581;(S)-α-Amino-2'-chloro-5-(phosphonomethyl)[1,1'-biphenyl]-3-propanoicacid;alpha-Amino-2'-chloro-5-(phosphonomethyl)(1,1'-biphenyl)-3-propanoic acid;(S)-ALPHA-AMINO-2'-CHLORO-5-(PHOSPHONOMETHYL)[1,1'-BIPHENYL]-3-PROPANOIC ACID;[1,1'-Biphenyl]-3-propanoic acid, α-amino-2'-chloro-5-(phosphonomethyl)-, (αS)-
- CBNumber:
- CB3153990
- Molecular Formula:
- C16H17ClNO5P
- Molecular Weight:
- 369.74
- MDL Number:
- MFCD09878263
- MOL File:
- 174575-17-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
SDZ 220-581 price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 33344 | SDZ 220-581 ≥98% | 174575-17-8 | 5mg | $61 | 2026-04-30 | Buy |
| Cayman Chemical | 33344 | SDZ 220-581 ≥98% | 174575-17-8 | 10mg | $116 | 2026-04-30 | Buy |
| Cayman Chemical | 33344 | SDZ 220-581 ≥98% | 174575-17-8 | 25mg | $273 | 2026-04-30 | Buy |
| Cayman Chemical | 33344 | SDZ 220-581 ≥98% | 174575-17-8 | 50mg | $424 | 2026-04-30 | Buy |
| Usbiological | 465977 | SDZ 220-581 | 174575-17-8 | 10mg | $453 | 2026-06-03 | Buy |
SDZ 220-581 Chemical Properties, Uses, Production
Uses
SDZ 220-581 is a competitive NMDA receptor antagonist.
Biological Activity
Competitive NMDA receptor antagonist (pK i = 7.7). Centrally active following oral administration (ED 50 < 3.2 mg/kg for protection against MES-induced seizures).
in vivo
SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action[1].
| Animal Model: | Male OF-l mice (18-26 g)[1] |
| Dosage: | 3.2 mg/kg, 10 mg/kg, 32 mg/kg |
| Administration: | Oral administration; for 24 hours |
| Result: | Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration. |
IC 50
NMDA Receptor
storage
Store at RT
SDZ 220-581 Preparation Products And Raw materials
Raw materials
Preparation Products
SDZ 220-581 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Atop-Pharma (Shanghai) Technology Co., Ltd. | +86 (21) 5196-9732 | China | 996 | 57 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 | info@adooq.cn | China | 2981 | 60 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2374 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9239 | 55 | |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3853 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
View Latest Price from SDZ 220-581 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | SDZ 220-581
174575-17-8
|
$30.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-10-28 | SDZ 220-581
174575-17-8
|
$73.00 | 10g | TargetMol Chemicals Inc. |
-
- SDZ 220-581
174575-17-8
- $30.00
- TargetMol Chemicals Inc.
-
- SDZ 220-581
174575-17-8
- $73.00
- TargetMol Chemicals Inc.
