Retinyl propionate
- CAS No.
- 7069-42-3
- Chemical Name:
- Retinyl propionate
- Synonyms
- VITAMIN A PROPIONATE;Retinol propionate;Einecs 230-363-2;Retinylpropionat;RETINYL PROPIOTE;Retinol,propanoate;RETINYL PROPIONATE;15-Retinol Propanoate;Vitamin A Impurity 37;Retinol, 15-propanoate
- CBNumber:
- CB3188398
- Molecular Formula:
- C23H34O2
- Molecular Weight:
- 342.51
- MDL Number:
- MFCD00129785
- MOL File:
- 7069-42-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 453.7±14.0 °C(Predicted) |
|---|---|
| Density | 0.963±0.06 g/cm3(Predicted) |
| vapor pressure | 0-0Pa at 20-96.2℃ |
| Flash point | 128 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Pale Yellow to Yellow |
| biological source | synthetic |
| BRN | 2475675 |
| Specific Activity | ~2500U/mg |
| Stability | Light Sensitive |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | 1S/C23H34O2/c1-7-22(24)25-17-15-19(3)11-8-10-18(2)13-14-21-20(4)12-9-16-23(21,5)6/h8,10-11,13-15H,7,9,12,16-17H2,1-6H3/b11-8+,14-13+,18-10+,19-15+ |
| InChIKey | SFRPDSKECHTFQA-ONOWFSFQSA-N |
| SMILES | CCC(=O)OC\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C |
| LogP | 9.12 at 25℃ |
| EWG's Food Scores | 6-9 |
| FDA UNII | 32JK994WMC |
| UNSPSC Code | 41116107 |
| NACRES | NA.79 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360-H413 |
| Precautionary statements | P201-P273-P308+P313 |
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn,T |
| Risk Statements | 38-63-53-61 |
| Safety Statements | 53-45 |
| WGK Germany | 1 |
| F | 1-8-10 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Aquatic Chronic 4 Repr. 1B |
| REACH Registrations | Active |
Retinyl propionate price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 87809 | Retinyl propionate ≥98.0% (sum of isomers, HPLC), ~2500U/mg | 7069-42-3 | 25g | $119 | 2026-04-30 | Buy |
| Sigma-Aldrich | 87809 | Retinyl propionate ≥98.0% (sum of isomers, HPLC), ~2500U/mg | 7069-42-3 | 100g | $331 | 2026-04-30 | Buy |
| Biosynth | W-110194 | Retinyl propionate | 7069-42-3 | 50g | $324 | 2026-06-05 | Buy |
| Biosynth | W-110194 | Retinyl propionate | 7069-42-3 | 100g | $629 | 2026-06-05 | Buy |
| Biosynth | W-110194 | Retinyl propionate | 7069-42-3 | 250g | $1527.5 | 2026-06-05 | Buy |
Retinyl propionate Chemical Properties, Uses, Production
Suggestions for use
Usage levels of retinyl propionate in skin care range from 0.1–0.4%. It is often paired with niacinamide because this B vitamin enhances the stability and bioavailability of retinyl propionate.
Description
Retinyl propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare".Similar to retinyl palmitate, retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together.
Chemical Properties
Thick Yellow Oil
Uses
Retinyl Propionate is a Vitamin A ester derivative. Retinyl Propionate is a hypermitotic agent that is used in cosmetic formulations.This compound contains an unknown cis isomer.
Biochem/physiol Actions
Retinyl propionate, a derivative of retinol, is a fatty acid that is used as a sample preparation for copper-complexed collagen[1]. In metabolic processes, retinyl propionate is metabolized primarily into retinol (ROL) in the viable epidermis and dermis whereas ROL is esterified into retinyl palmitate (RPalm) and metabolized into the inactive retinoid 14‐hydroxy‐4,14‐retro‐retinol (14‐HRR)[2]. Retinol and its derivatives effectively intervene in the skin aging process. The matrix effect of retinyl propionate can be seen in the skin cells, bone cells, and cartilage tissue. Retinyl propionate has been shown to increase calcium pantothenate transport rates in human serum and also has a film-forming polymer effect.
Side effects
Side effects of using retinol may include: redness, irritation, burning, itching, dry skin, flaking and peeling of the skin, increased sensitivity to the sun, and skin cancer.
Structure and conformation
Retinyl propionate is closest in molecular size to pure retinoic acid with just three additional carbons. Vitamin A palmitate has an additional 16 carbons, making it too large to reach the dermis effectively.
References
[1] Wang Q, et al. The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging. Journal of Cosmetic Dermatology, 2023; 22: 2040-2049.
[2] Yang Y, et al. Hydrophobically modified inulin based nanoemulsions for enhanced stability and transdermal delivery of retinyl propionate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022; 653: 129883.
Retinyl propionate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Aiyu Technology Co.,Ltd | 18588406486 | courage.you@foxmail.com | China | 211 | 58 |
| Puripharm Co., Ltd. | 0572-2745768-1 13167223168;13167223168 | sales@puripharm.com | China | 299 | 65 |
| Shandong Juntai Pharmaceutical Co., Ltd | 18963498209 18963498209 | juntai@h2opharm.com | China | 289 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
View Latest Price from Retinyl propionate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | Retinyl propionate
7069-42-3
|
$1.40-32.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-09 | Retinyl propionate;Vitamin A Propionate
7069-42-3
|
≥99% | 20tons | Chongqing Zhihe Biopharmaceutical Co., Ltd. | |||
 |
2026-08-08 | RETINYL PROPIONATE
7069-42-3
|
1KG | 98.0% | 500KG | Hangzhou ICH Biofarm Co., Ltd |
-
- Retinyl propionate
7069-42-3
- $1.40-32.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Retinyl propionate;Vitamin A Propionate
7069-42-3
- ≥99%
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
-
- RETINYL PROPIONATE
7069-42-3
- 98.0%
- Hangzhou ICH Biofarm Co., Ltd
