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Retinyl propionate

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Retinyl propionate manufacturers

  • RETINYL PROPIONATE
  • RETINYL PROPIONATE pictures
  • 2026-08-08
  • CAS:7069-42-3
  • Min. Order: 1KG
  • Purity: 98.0%
  • Supply Ability: 500KG
Retinyl propionate Basic information
Suggestions for use
Product Name:Retinyl propionate
Synonyms:RETINYL PROPIONATE;Retinol,propanoate;ALL TRANS-RETINOL PROPIONATE;VITAMIN-A-PROPIONATE, ~2500 U/MG*;VITAMIN-A-PROPIONATE 2500 U MG 98+%;Retinylpropionat;Propanoic acid (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2,4,6,8-nonatetrenyl ester;Retinol propionate
CAS:7069-42-3
MF:C23H34O2
MW:342.51
EINECS:230-363-2
Product Categories:supplement;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids
Mol File:7069-42-3.mol
Retinyl propionate Structure
Retinyl propionate Chemical Properties
Boiling point 453.7±14.0 °C(Predicted)
density 0.963±0.06 g/cm3(Predicted)
vapor pressure 0-0Pa at 20-96.2℃
Fp 128 °C
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form Oil
color Pale Yellow to Yellow
biological sourcesynthetic
Specific Activity~2500U/mg
BRN 2475675
Stability:Light Sensitive
Cosmetics Ingredients FunctionsSKIN CONDITIONING
InChI1S/C23H34O2/c1-7-22(24)25-17-15-19(3)11-8-10-18(2)13-14-21-20(4)12-9-16-23(21,5)6/h8,10-11,13-15H,7,9,12,16-17H2,1-6H3/b11-8+,14-13+,18-10+,19-15+
InChIKeySFRPDSKECHTFQA-ONOWFSFQSA-N
SMILESCCC(=O)OC\C=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
LogP9.12 at 25℃
Safety Information
Hazard Codes Xn,T
Risk Statements 38-63-53-61
Safety Statements 53-45
WGK Germany 1
1-8-10
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAquatic Chronic 4
Repr. 1B
MSDS Information
ProviderLanguage
SigmaAldrich English
Retinyl propionate Usage And Synthesis
Suggestions for useUsage levels of retinyl propionate in skin care range from 0.1–0.4%. It is often paired with niacinamide because this B vitamin enhances the stability and bioavailability of retinyl propionate.
DescriptionRetinyl propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare".Similar to retinyl palmitate, retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together.
Chemical PropertiesThick Yellow Oil
UsesRetinyl Propionate is a Vitamin A ester derivative. Retinyl Propionate is a hypermitotic agent that is used in cosmetic formulations.This compound contains an unknown cis isomer.
Biochem/physiol ActionsRetinyl propionate, a derivative of retinol, is a fatty acid that is used as a sample preparation for copper-complexed collagen[1]. In metabolic processes, retinyl propionate is metabolized primarily into retinol (ROL) in the viable epidermis and dermis whereas ROL is esterified into retinyl palmitate (RPalm) and metabolized into the inactive retinoid 14‐hydroxy‐4,14‐retro‐retinol (14‐HRR)[2]. Retinol and its derivatives effectively intervene in the skin aging process. The matrix effect of retinyl propionate can be seen in the skin cells, bone cells, and cartilage tissue. Retinyl propionate has been shown to increase calcium pantothenate transport rates in human serum and also has a film-forming polymer effect.
Side effectsSide effects of using retinol may include: redness, irritation, burning, itching, dry skin, flaking and peeling of the skin, increased sensitivity to the sun, and skin cancer.
Structure and conformationRetinyl propionate is closest in molecular size to pure retinoic acid with just three additional carbons. Vitamin A palmitate has an additional 16 carbons, making it too large to reach the dermis effectively.
References[1] Wang Q, et al. The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging. Journal of Cosmetic Dermatology, 2023; 22: 2040-2049.
[2] Yang Y, et al. Hydrophobically modified inulin based nanoemulsions for enhanced stability and transdermal delivery of retinyl propionate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022; 653: 129883.
Retinyl propionate Preparation Products And Raw materials
Raw materialsVitamin A-->Propionic-2,3-14C1 acid (8CI)
Tag:Retinyl propionate(7069-42-3) Related Product Information
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