Olivetol
- CAS No.
- 500-66-3
- Chemical Name:
- Olivetol
- Synonyms
- 1,3-Benzenediol, 5-pentyl-;5-PENTYLRESORCINOL;5-pentylbenzene-1,3-diol;3,5-dihydroxyamylbenzene;Olivetol Powder;CL213;ivetoL;Olidol;OLIVETOL;Oilvetol
- CBNumber:
- CB3204779
- Molecular Formula:
- C11H16O2
- Molecular Weight:
- 180.24
- MDL Number:
- MFCD00002293
- MOL File:
- 500-66-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 46-48 °C(lit.) |
|---|---|
| Boiling point | 164 °C |
| Density | 1.068±0.06 g/cm3(Predicted) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.59±0.10(Predicted) |
| color | Colourless to Beige |
| Stability | Light Sensitive |
| InChI | InChI=1S/C11H16O2/c1-2-3-4-5-9-6-10(12)8-11(13)7-9/h6-8,12-13H,2-5H2,1H3 |
| InChIKey | IRMPFYJSHJGOPE-UHFFFAOYSA-N |
| SMILES | C1(O)=CC(CCCCC)=CC(O)=C1 |
| CAS DataBase Reference | 500-66-3(CAS DataBase Reference) |
| FDA UNII | 65OP0NEZ1P |
| NIST Chemistry Reference | 1,3-Benzenediol, 5-pentyl-(500-66-3) |
| EPA Substance Registry System | Olivetol (500-66-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H400 |
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 |
| target organs | Central nervous system,Blood, Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/39 |
| WGK Germany | 3 |
| RTECS | VH2880000 |
| HS Code | 2907290090 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 3 Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1B STOT SE 1 Oral STOT SE 2 Oral |
Olivetol price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 152633 | Olivetol 95% | 500-66-3 | 1g | $70.1 | 2026-04-30 | Buy |
| TCI Chemical | O0415 | Olivetol min. 98.0 % | 500-66-3 | 1G | $69 | 2026-04-30 | Buy |
| TCI Chemical | O0415 | Olivetol min. 98.0 % | 500-66-3 | 5G | $208 | 2026-04-30 | Buy |
| Cayman Chemical | 35202 | Olivetol ≥98% | 500-66-3 | 10mg | $38 | 2026-04-30 | Buy |
| Cayman Chemical | 35202 | Olivetol ≥98% | 500-66-3 | 25mg | $66 | 2026-04-30 | Buy |
Olivetol Chemical Properties, Uses, Production
Chemical Properties
Olivetol is an off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.
Physical properties
light purple to brown crystalline mass.
Uses
Olivetol was used as a template molecule in the synthesis of molecularly imprinted polymer (MIP). It was also used as an inhibitor of (S)-mephenytoin 4'-hydroxylase activity of recombinant CYP2C19.
Application
Olivetol is a precursor in various syntheses of tetrahydrocannabinol.
Preparation
olivetol can also be formed through hydrolysis of intermediate polyketide CoAs or spontaneous cyclization.
Definition
ChEBI: Olivetol is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group. It has a role as a lichen metabolite.
Synthesis Reference(s)
The Journal of Organic Chemistry, 42, p. 3456, 1977 DOI: 10.1021/jo00441a036
General Description
Olivetol appears as off-white crystals or olive to light purple waxy solid. Forms monohydrate (melting point: 102-106°F). (NTP, 1992)
Air & Water Reactions
Sensitive to air. Insoluble in water.
Reactivity Profile
Olivetol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.
Fire Hazard
Olivetol is probably combustible.
Biological Activity
Olivetol (5-Pentylresorcinol, 5-n-Amylresorcinol) is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.
Safety
Olivetol is still a very new product. It has not been researched nearly enough to prove it's safe to use. So far, no one has reported any adverse side effects as far as we know. Until more information is available, carefully control your THC intake instead of relying on an untested gelcap.
Mode of action
When you look at olivetol's molecular structure, it'll look very familiar. It's as if someone took a THC molecule and sliced it in two. Olivetol, like THC, works by binding with the CB1 receptors that exist all over your body and brain. But, olivetol is thought to be smaller and stickier than THC, so that helps it reduce a raging high in two ways. First, it slips into any open receptors before THC can get there to block them—so you won't get any higher. Second, it bumps into THC molecules that are already lodged in a CB1 receptor to knock them loose and take their place. That's how it brings you down.
According to numerous personal accounts, olivetol works, but we don't know exactly how it does so. More research and investigation is needed, but in theory it's very similar to how Narcan acts to reverse opiate overdoses.
Olivetol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Blazer Biomedical Technology Co., Ltd. | 0523-86112008 13915404123 | sales@blazerbio.com | China | 285 | 58 |
| Jinan Cen Ben Medical Technology Co., Ltd | 14793566 | info@cenpharm.com | China | 785 | 58 |
| Shenzhen Zhaoke Biotechnology Co., Ltd | 18271904430 | 1070737105@qq.com | China | 149 | 58 |
| Suzhou Jinglige Technology Co., Ltd | 18551175068 | jinglige888@163.com | China | 248 | 58 |
| Suzhou Hosyn Pharm Ltd. | 17621975170; 17621975170 | sales@hosynpharm.com | China | 1722 | 58 |
| Changzhou Share Chemical Co., Ltd | 0519-82619998 | wu@sharechem.com | China | 29 | 54 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. | 21-54820552 17702105771 | 188738128@qq.com | China | 300 | 66 |
Related articles
- Olivetol: Natural Occurrence, Biotransformation and Electrochemical Detection
- Olivetol, sourced from tropical plants, undergoes biotransformation, yielding three metabolites. Electrochemical detection aid....
- May 8,2024
- Olivetol: A Promising Compound with Antioxidant and Anticholinergic Properties
- Olivetol shows strong antioxidant activity, effective enzyme inhibition, and potential therapeutic applications in oxidative s....
- Jan 5,2024
- Can Olivetol treat obesity?
- Olivetol was able to inhibit the storage of excess fat in the liver caused by obesity (steatohepatitis) by lowering the levels....
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View Latest Price from Olivetol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-15 | Olivetol
500-66-3
|
1KG | 99% | 50mt | Jinan Finer Chemical Co., Ltd | ||
 |
2026-09-15 | Olivetol
500-66-3
|
$666.00-999.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-09-14 | Olivetol
500-66-3
|
$1.00 | 1g | 99% | 1000kg | RongNa Biotechnology Co.,Ltd |
