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5'-Chloro-2'-hydroxy-4'-methylacetophenone

5'-Chloro-2'-hydroxy-4'-methylacetophenone Structure
5'-Chloro-2'-hydroxy-4'-methylacetophenone structure
CAS No.
28480-70-8
Chemical Name:
5'-Chloro-2'-hydroxy-4'-methylacetophenone
Synonyms
2-ACETYL-4-CHLORO-5-METHYLPHENOL;4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE;5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE;5'-Cloro-2'-Hydroxy-4'-Methylacetophenone;5'-Chooro-2'-Hydroxy-4'-Methylacetophenone;5'-Chloro-2'-hydroxy-4'-methylacetophenone;1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE;5'-Chloro-2'-hydroxy-4'-methylacetophenone >5'-Chloro-2'-hydroxy-4'-methylacetophenone 98%;Ethanone, 1-(5-chloro-2-hydroxy-4-methylphenyl)-
CBNumber:
CB3212213
Molecular Formula:
C9H9ClO2
Molecular Weight:
184.62
MDL Number:
MFCD00191920
MOL File:
28480-70-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:50
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5'-Chloro-2'-hydroxy-4'-methylacetophenone Properties

Melting point 70-73 °C(lit.)
Boiling point 137 °C / 15mmHg
Density 1.250±0.06 g/cm3(Predicted)
storage temp. RT, stored under nitrogen
pka 9.84±0.23(Predicted)
form powder to crystal
color White to Light yellow
InChI InChI=1S/C9H9ClO2/c1-5-3-9(12)7(6(2)11)4-8(5)10/h3-4,12H,1-2H3
InChIKey HDUSGGZSLVCDKY-UHFFFAOYSA-N
SMILES C(=O)(C1=CC(Cl)=C(C)C=C1O)C
CAS DataBase Reference 28480-70-8(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  2914.50.3000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

5'-Chloro-2'-hydroxy-4'-methylacetophenone price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 415758 5′-Chloro-2′-hydroxy-4′-methylacetophenone 98% 28480-70-8 5g $42.6 2023-06-20 Buy
TCI Chemical C1629 5'-Chloro-2'-hydroxy-4'-methylacetophenone >95.0%(GC) 28480-70-8 5g $17 2026-04-30 Buy
TCI Chemical C1629 5'-Chloro-2'-hydroxy-4'-methylacetophenone >95.0%(GC) 28480-70-8 25g $51 2026-04-30 Buy
Apolloscientific OR1116 5'-Chloro-2'-hydroxy-4'-methylacetophenone 98% 28480-70-8 1g $21 2026-06-04 Buy
Apolloscientific OR1116 5'-Chloro-2'-hydroxy-4'-methylacetophenone 98% 28480-70-8 5g $24 2026-06-04 Buy
Product number Packaging Price Buy
415758 5g $42.6 Buy
C1629 5g $17 Buy
C1629 25g $51 Buy
OR1116 1g $21 Buy
OR1116 5g $24 Buy

5'-Chloro-2'-hydroxy-4'-methylacetophenone Chemical Properties, Uses, Production

Uses

5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:

  • chalcones, required for the synthesis of novel pyrazoline derivatives
  • 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
  • 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)

Preparation

Preparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%).

General Description

5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone.

5'-Chloro-2'-hydroxy-4'-methylacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

6-Chloro-3-formyl-7-methylchromone 5'-Chloro-2'-hydroxy-4'-methyl-3'-nitroacetophenone

5'-Chloro-2'-hydroxy-4'-methylacetophenone Suppliers

Global Suppliers ( 124)
Supplier Tel Email Country ProdList Advantage
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 029-029-81120477 17792793610 1033@dideu.com China 9990 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
Supplier Advantage
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 58
J & K SCIENTIFIC LTD. 76
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Topbiochem Technology Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 80

View Latest Price from 5'-Chloro-2'-hydroxy-4'-methylacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE pictures 2026-08-07 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
28480-70-8
 1KG 98 Shaanxi Dideu Medichem Co. Ltd
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE pictures 2026-06-30 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
28480-70-8
 1KG 97.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

5'-Chloro-2'-hydroxy-4'-methylacetophenone Spectrum

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE(28480-70-8)MS5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE(28480-70-8)1HNMR5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE(28480-70-8)IR15'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE(28480-70-8)IR2

28480-70-8 (5'-Chloro-2'-hydroxy-4'-methylacetophenone) Related Search:

5'-Chloro-2'-hydroxy-3'-nitroacetophenone 5-Chloro-2-hydroxy-4-methylbenzophenone 5'-Chloro-2'-hydroxy-4'-methylacetophenone 2'-Hydroxy-4'-methylacetophenone 6-Chloro-7-methylchromone
6-Chloro-7-methylflavone 6,4'-Dichloro-7-methylflavone 6-Chloro-3-formyl-7-methylchromone 5'-Chloro-2'-hydroxy-4'-methylpropiophenone 5'-Chloro-2'-hydroxy-4'-methyl-2-phenyl acetophenone
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5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE 4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE 1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE 2-ACETYL-4-CHLORO-5-METHYLPHENOL 5'-Chooro-2'-Hydroxy-4'-Methylacetophenone JRH-01005, 1-(5-Chloro-2-hydroxy-4-methylphenyl)ethanone, 97% 4-Acetyl-2-chloro-5-hydroxytoluene 2-Acetyl-4-chloro-5-methylphenol 5'-Chloro-2'-hydroxy-4'-methylacetophenone 98% 5'-Chloro-2'-hydroxy-4'-methylacetophenone > Ethanone, 1-(5-chloro-2-hydroxy-4-methylphenyl)- 5'-Cloro-2'-Hydroxy-4'-Methylacetophenone 5′-Chloro-2′-hydroxy-4′-methylacetophenone, CAS 28480-70-8 5'-Chloro-2'-hydroxy-4'-methylacetophenone 28480-70-8 ClC6H2OHCH3COCH3 C9 Carbonyl Compounds Building Blocks Organic Building Blocks Ketones Ketones Aromatic Acetophenones & Derivatives (substituted) C9 Carbonyl Compounds