2-Methyl-1,3-cyclohexanedione
- CAS No.
- 1193-55-1
- Chemical Name:
- 2-Methyl-1,3-cyclohexanedione
- Synonyms
- 2-METHYLCYCLOHEXANE-1,3-DIONE;1,3-Cyclohexanedione, 2-methyl-;2-MECHD;NSC 54460;2-METHYL-1,3-CYCLOHEXANDIONE;Acridine Related Compound 10;1-Methyl-2,6-cyclohexanedione;2-METHYL-1,3-CYCLOHEXANEDIONE;1,3-DIMETHYLCYCLOADIPIC KETONE;2-Methyl-1,3-cyclohexanedione>
- CBNumber:
- CB3214752
- Molecular Formula:
- C7H10O2
- Molecular Weight:
- 126.15
- MDL Number:
- MFCD00001587
- MOL File:
- 1193-55-1.mol
- MSDS File:
- SDS
| Melting point | 206-208 °C (lit.) |
|---|---|
| Boiling point | 194.28°C (rough estimate) |
| Density | 1.0579 (rough estimate) |
| refractive index | 1.4660 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | methanol: 0.1 g/mL, clear |
| form | Powder, Crystals or Crystalline Powder |
| pka | 5.58±0.25(Predicted) |
| color | Off-white to salmon to pale brown |
| Water Solubility | INSOLUBLE |
| Sensitive | Hygroscopic |
| BRN | 1281598 |
| InChIKey | VSGJHHIAMHUZKF-UHFFFAOYSA-N |
| LogP | -0.390 (est) |
| CAS DataBase Reference | 1193-55-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Cyclohexanedione, 2-methyl-(1193-55-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29142900 | |||||||||
| NFPA 704 |
|
2-Methyl-1,3-cyclohexanedione price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M37935 | 2-Methyl-1,3-cyclohexanedione 97% | 1193-55-1 | 25g | $144.4 | 2025-07-31 | Buy |
| Sigma-Aldrich | M37935 | 2-Methyl-1,3-cyclohexanedione 97% | 1193-55-1 | 100g | $557 | 2025-07-31 | Buy |
| TCI Chemical | M1133 | 2-Methyl-1,3-cyclohexanedione >98.0%(GC)(T) | 1193-55-1 | 5g | $71 | 2025-07-31 | Buy |
| TCI Chemical | M1133 | 2-Methyl-1,3-cyclohexanedione >98.0%(GC)(T) | 1193-55-1 | 25g | $284 | 2025-07-31 | Buy |
| Cayman Chemical | 10007138 | 2-methyl-1,3-Cyclohexanedione ≥95% | 1193-55-1 | 1g | $21 | 2024-03-01 | Buy |
2-Methyl-1,3-cyclohexanedione Chemical Properties,Uses,Production
Description
2-
Chemical Properties
White to salmon powder
Uses
An important starting material, exemplified in a formal synthesis of acorone.1
Uses
2-Methylcyclohexane-1,3-dione acts as a synthetic intermediate. It is an important starting material, exemplified in a formal synthesis of acorone. It is also used in Organic Synthesis, Pharmaceuticals, Agrochemicals.
Synthesis
504-02-9
1193-55-1
In a reactor equipped with a stirrer, 300 parts of methanol, 56 parts of a 50% aqueous solution of dimethylamine and 56 parts of 1,3-cyclohexanedione were added and the mixture was warmed up to 30 °C. A 37% aqueous solution of formaldehyde was added dropwise over a period of 1 hour. After addition, the reaction solution was maintained at 40°C for 3 hours. The unreacted 1,3-cyclohexanedione content was monitored by HPLC to confirm the reaction endpoint. Subsequently, 10 portions of 5% palladium-carbon catalyst were added to the reaction mixture and the reaction was carried out at 30°C and atmospheric pressure with hydrogen gas passed for 15 hours. The unreacted 2-dimethylaminomethyl-1,3-cyclohexanedione content was detected by high performance liquid chromatography to confirm the completion of the reaction. At the end of the reaction, the catalyst was removed by filtration at 30 °C, 300 parts of water were added to the filtrate, methanol was removed by distillation, and the residue was adjusted with 35% hydrochloric acid to pH 6. The precipitate was collected by filtration, washed with water and dried at 70 °C to give 54.8 parts of 2-methyl-1,3-cyclohexanedione as dry cake (yield: 87.0%). HPLC analysis showed that the purity of 2-methyl-1,3-cyclohexanedione in the dry cake was 97.2%. The melting point of the dried cake was 206°-208°C (literature value: 207°-209°C). FD-MS analysis showed that the dried cake had a peak at m/z 126, which was consistent with the theoretical molecular weight.
References
[1] Patent: US5276198, 1994, A
2-Methyl-1,3-cyclohexanedione Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Nanjing jinheyou Trading Co., Ltd. | 15705188088 | admin@jheyou.com | CHINA | 1268 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8829 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12332 | 58 |
View Lastest Price from 2-Methyl-1,3-cyclohexanedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 2-Methyl-1,3-cyclohexanedione
1193-55-1
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2020-06-02 | 2-Methyl-1,3-cyclohexanedione in stock Factory
1193-55-1
|
US $1.00 / KG | 1KG | TOP 3 Factory in China | Top 3 largest production capacity Factory | Chemwill Asia Co.,Ltd. | |
 |
2019-11-08 | 2-Methyl-1,3-cyclohexanedione
1193-55-1
|
US $0.00 / g | 1g | 98%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 2-Methyl-1,3-cyclohexanedione
1193-55-1
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Methyl-1,3-cyclohexanedione in stock Factory
1193-55-1
- US $1.00 / KG
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- 2-Methyl-1,3-cyclohexanedione
1193-55-1
- US $0.00 / g
- 98%min
- Nanjing jinheyou Trading Co., Ltd.
