2-Methyl-1,3-cyclohexanedione
- CAS No.
- 1193-55-1
- Chemical Name:
- 2-Methyl-1,3-cyclohexanedione
- Synonyms
- 2-METHYLCYCLOHEXANE-1,3-DIONE;1,3-Cyclohexanedione, 2-methyl-;2-MECHD;NSC 54460;2-METHYL-1,3-CYCLOHEXANDIONE;Acridine Related Compound 10;1-Methyl-2,6-cyclohexanedione;2-METHYL-1,3-CYCLOHEXANEDIONE;1,3-DIMETHYLCYCLOADIPIC KETONE;2-Methyl-1,3-cyclohexanedione>
- CBNumber:
- CB3214752
- Molecular Formula:
- C7H10O2
- Molecular Weight:
- 126.15
- MDL Number:
- MFCD00001587
- MOL File:
- 1193-55-1.mol
- MSDS File:
- SDS
| Melting point | 206-208 °C (lit.) |
|---|---|
| Boiling point | 194.28°C (rough estimate) |
| Density | 1.0579 (rough estimate) |
| refractive index | 1.4660 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | methanol: 0.1 g/mL, clear |
| form | Powder, Crystals or Crystalline Powder |
| pka | 5.58±0.25(Predicted) |
| color | Off-white to salmon to pale brown |
| Water Solubility | INSOLUBLE |
| Sensitive | Hygroscopic |
| BRN | 1281598 |
| InChI | 1S/C7H10O2/c1-5-6(8)3-2-4-7(5)9/h5H,2-4H2,1H3 |
| InChIKey | VSGJHHIAMHUZKF-UHFFFAOYSA-N |
| SMILES | CC1C(=O)CCCC1=O |
| LogP | -0.390 (est) |
| CAS DataBase Reference | 1193-55-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Cyclohexanedione, 2-methyl-(1193-55-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29142900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-Methyl-1,3-cyclohexanedione price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M37935 | 2-Methyl-1,3-cyclohexanedione 97% | 1193-55-1 | 25g | $162 | 2026-04-30 | Buy |
| Sigma-Aldrich | M37935 | 2-Methyl-1,3-cyclohexanedione 97% | 1193-55-1 | 100g | $593 | 2026-04-30 | Buy |
| TCI Chemical | M1133 | 2-Methyl-1,3-cyclohexanedione >98.0%(GC)(T) | 1193-55-1 | 5g | $78 | 2026-04-30 | Buy |
| TCI Chemical | M1133 | 2-Methyl-1,3-cyclohexanedione >98.0%(GC)(T) | 1193-55-1 | 25g | $310 | 2026-04-30 | Buy |
| Cayman Chemical | 10007138 | 2-methyl-1,3-Cyclohexanedione ≥95% | 1193-55-1 | 1g | $24 | 2026-04-30 | Buy |
2-Methyl-1,3-cyclohexanedione Chemical Properties,Uses,Production
Description
2-
Chemical Properties
White to salmon powder
Uses
An important starting material, exemplified in a formal synthesis of acorone.1
Uses
2-Methylcyclohexane-1,3-dione acts as a synthetic intermediate. It is an important starting material, exemplified in a formal synthesis of acorone. It is also used in Organic Synthesis, Pharmaceuticals, Agrochemicals.
Synthesis
504-02-9
1193-55-1
In a reactor equipped with a stirrer, 300 parts of methanol, 56 parts of a 50% aqueous solution of dimethylamine and 56 parts of 1,3-cyclohexanedione were added and the mixture was warmed up to 30 °C. A 37% aqueous solution of formaldehyde was added dropwise over a period of 1 hour. After addition, the reaction solution was maintained at 40°C for 3 hours. The unreacted 1,3-cyclohexanedione content was monitored by HPLC to confirm the reaction endpoint. Subsequently, 10 portions of 5% palladium-carbon catalyst were added to the reaction mixture and the reaction was carried out at 30°C and atmospheric pressure with hydrogen gas passed for 15 hours. The unreacted 2-dimethylaminomethyl-1,3-cyclohexanedione content was detected by high performance liquid chromatography to confirm the completion of the reaction. At the end of the reaction, the catalyst was removed by filtration at 30 °C, 300 parts of water were added to the filtrate, methanol was removed by distillation, and the residue was adjusted with 35% hydrochloric acid to pH 6. The precipitate was collected by filtration, washed with water and dried at 70 °C to give 54.8 parts of 2-methyl-1,3-cyclohexanedione as dry cake (yield: 87.0%). HPLC analysis showed that the purity of 2-methyl-1,3-cyclohexanedione in the dry cake was 97.2%. The melting point of the dried cake was 206°-208°C (literature value: 207°-209°C). FD-MS analysis showed that the dried cake had a peak at m/z 126, which was consistent with the theoretical molecular weight.
References
[1] Patent: US5276198, 1994, A
2-Methyl-1,3-cyclohexanedione Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing TianyiHenghua Technology Co., Ltd. | 15086758486; 15086758486 | chemtyhh@163.com | China | 93 | 58 |
| Anhui Xinying Technology Co., Ltd | 17356895373 | sales@xinying-chem.com | China | 133 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Bridge Organics | +1269-649-4200 | ab@bridgeorganics.com | United States | 160 | 55 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Lastest Price from 2-Methyl-1,3-cyclohexanedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 2-Methyl-1,3-cyclohexanedione
1193-55-1
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2020-06-02 | 2-Methyl-1,3-cyclohexanedione in stock Factory
1193-55-1
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. | ||
 |
2019-11-08 | 2-Methyl-1,3-cyclohexanedione
1193-55-1
|
1g | 98%min | 20kg/month | Nanjing jinheyou Trading Co., Ltd. |
-
- 2-Methyl-1,3-cyclohexanedione
1193-55-1
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Methyl-1,3-cyclohexanedione in stock Factory
1193-55-1
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- 2-Methyl-1,3-cyclohexanedione
1193-55-1
- $0.00
- 98%min
- Nanjing jinheyou Trading Co., Ltd.
