2-Methyl-5,7-dihydroxychromone
- CAS No.
- 1013-69-0
- Chemical Name:
- 2-Methyl-5,7-dihydroxychromone
- Synonyms
- Noreugenin;reugenin;Noreugenin, 10 mM in DMSO;2-Methyl-5,7-dihydroxychromone;5,7-dihydroxy-2-methylchromen-4-one;5,7-Dihydroxy-2-methyl-4H-1-benzopyran-4-one;2-Methyl-5,7-dihydroxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one,5,7-dihydroxy-2-methyl-
- CBNumber:
- CB32197071
- Molecular Formula:
- C10H8O4
- Molecular Weight:
- 192.17
- MDL Number:
- MFCD03001435
- MOL File:
- 1013-69-0.mol
- MSDS File:
- SDS
| Melting point | 279 °C |
|---|---|
| Boiling point | 394.6±42.0 °C(Predicted) |
| Density | 1.456±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 250 mg/mL (1300.93 mM); Water: < 0.1 mg/mL (insoluble) |
| form | Solid |
| pka | 6.58±0.40(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C10H8O4/c1-5-2-7(12)10-8(13)3-6(11)4-9(10)14-5/h2-4,11,13H,1H3 |
| InChIKey | NCUJRUDLFCGVOE-UHFFFAOYSA-N |
| SMILES | C1(C)OC2=CC(O)=CC(O)=C2C(=O)C=1 |
| FDA UNII | M0KFC1Q5JC |
2-Methyl-5,7-dihydroxychromone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FN42576 | Noreugenin | 1013-69-0 | 1mg | $220 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FN42576 | Noreugenin | 1013-69-0 | 2mg | $340 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0299002 | 5,7-DIHYDROXY-2-METHYL-4H-1-BENZOPYRAN-4-ONE 95.00% | 1013-69-0 | 5MG | $505.23 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FN42576 | Noreugenin | 1013-69-0 | 5mg | $550 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FN42576 | Noreugenin | 1013-69-0 | 10mg | $850 | 2021-12-16 | Buy |
2-Methyl-5,7-dihydroxychromone Chemical Properties,Uses,Production
Uses
Noreugenin, 5,7-dihydroxy-2-methyl-4H-chromen-4-one, is a new chromone from Aloe arborescens. (Amaryllidaceae)[1].
Definition
ChEBI: Noreugenin is a member of the class of chromones in which the 1,4-benzopyrone skeleton is substituted with a methyl group at position 2 and with hydroxy groups at positions 5 and 7. A natural product, it is found in Pisonia aculeata. It has a role as a plant metabolite. It is a member of chromones and a member of resorcinols. It is a conjugate acid of a noreugenin(1-).
Synthesis
1162-81-8
1013-69-0
The general procedure for the synthesis of 5,7-dihydroxy-2-methyl-4H-benzopyran-4-one from the compound (CAS:1162-81-8) is as follows: 2-methyl-3-acetyl-5,7-diacetoxychromanone (15.9 g, 0.05 mol) was placed in a 1 L three-necked flask and 400 mL of sodium carbonate solution (10 mL) was added. The mixture was heated to reflux for 2 hours. After the reaction was completed, it was cooled to room temperature and filtered to remove insoluble material. The filtrate was adjusted to pH 7~8 with hydrochloric acid, at which time a large amount of solid precipitated. The solution was further cooled to below 10°C, filtered and the solids were collected. The filter cake was dried under vacuum at 40 °C for 4 h to give 8.98 g of off-white solid powder in 93.6% yield. The structure of the final product 2-methyl-5,7-dihydroxychromone was confirmed by 1H-NMR and mass spectrometry.
References
[1] Wang Y, et al. Aspergchromones A and B, two new polyketides from the marine sponge-associated fungus Aspergillus sp. SCSIO XWS03F03. J Asian Nat Prod Res. 2017 Jul;19(7):684-690. DOI:10.1080/14786419.2014.951931
2-Methyl-5,7-dihydroxychromone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5744 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3995 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10242 | 58 |
View Lastest Price from 2-Methyl-5,7-dihydroxychromone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-30 | Noreugenin
1013-69-0
|
US $56.00-197.00 / mg | 99.62% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-07-16 | 2-Methyl-5,7-dihydroxychromone
1013-69-0
|
US $0.00-0.00 / KG | 1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-02-07 | Noreugenin
1013-69-0
|
US $9.80 / KG | 1KG | ＞98%HPLC | 20 tons | Career Henan Chemical Co |
-
- Noreugenin
1013-69-0
- US $56.00-197.00 / mg
- 99.62%
- TargetMol Chemicals Inc.
-
- 2-Methyl-5,7-dihydroxychromone
1013-69-0
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Noreugenin
1013-69-0
- US $9.80 / KG
- ＞98%HPLC
- Career Henan Chemical Co
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