1-Chloroethyl ethyl carbonate
- CAS No.
- 50893-36-2
- Chemical Name:
- 1-Chloroethyl ethyl carbonate
- Synonyms
- CEEC;1-CHLOROETHYL ETHYL;1-chlorobutyl carbonate;1-CHLORODIETHYL CARBONATE;1-Chloroethyl ethyl carbote;1-chloroethy ethyl carbonate;1-CHLOROETHYL ETHYL CARBONATE;Ethyl-(1-chloroethyl)-carbonate;Carbonic acid 1-chloroethyl=ethyl;1-Chloroethyl Ethyl Carbonate >
- CBNumber:
- CB3229068
- Molecular Formula:
- C5H9ClO3
- Molecular Weight:
- 152.58
- MDL Number:
- MFCD00040523
- MOL File:
- 50893-36-2.mol
- MSDS File:
- SDS
| Melting point | 159-161°C |
|---|---|
| Boiling point | 159-161 °C(lit.) |
| Density | 1.136 g/mL at 20 °C(lit.) |
| refractive index |
n |
| Flash point | 65°C |
| storage temp. | 2-8°C |
| solubility | Chloroform |
| form | Oil |
| color | Colourless |
| BRN | 3536477 |
| Stability | Moisture Sensitive |
| InChI | 1S/C5H9ClO3/c1-3-8-5(7)9-4(2)6/h4H,3H2,1-2H3 |
| InChIKey | YVRGKFXJZCTTRB-UHFFFAOYSA-N |
| SMILES | CCOC(=O)OC(C)Cl |
| CAS DataBase Reference | 50893-36-2(CAS DataBase Reference) |
| EPA Substance Registry System | Carbonic acid, 1-chloroethyl ethyl ester (50893-36-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H319 | |||||||||
| Precautionary statements | P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-28 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29209090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
1-Chloroethyl ethyl carbonate price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C1056 | 1-Chloroethyl Ethyl Carbonate >98.0%(GC) | 50893-36-2 | 25g | $85 | 2026-04-30 | Buy |
| TCI Chemical | C1056 | 1-Chloroethyl Ethyl Carbonate >98.0%(GC) | 50893-36-2 | 100g | $219 | 2026-04-30 | Buy |
| TRC | TRC-C984693-5ML | 1-Chloroethyl Ethyl Carbonate | 50893-36-2 | 5mL | $64 | 2026-06-03 | Buy |
| TRC | TRC-C984693-50MG | 1-Chloroethyl Ethyl Carbonate | 50893-36-2 | 50mg | $45 | 2026-06-03 | Buy |
| TRC | TRC-C984693-10ML | 1-Chloroethyl Ethyl Carbonate | 50893-36-2 | 10mL | $78 | 2026-06-03 | Buy |
1-Chloroethyl ethyl carbonate Chemical Properties, Uses, Production
Chemical Properties
Clear pale yellowish liquid
Uses
1-Chloroethyl ethyl carbonate is used as an intermediate in drugs such as candesartan cilexetil and cefotetan cilexetil.
Synthesis
64-17-5
50893-53-3
50893-36-2
71.5 g (0.5 mmol) of 1-chloroethyl chloroformate, 40 g of ethanol and 52.0 g of triethylamine were sequentially added to 250 mL of toluene solution under cooling at 0°C. After the addition was completed, the reaction system was kept stirred at 0°C for about 2 hours. Subsequently, the reaction system was slowly warmed to room temperature and the reaction was continued for 1 hour. Upon completion of the reaction, the solid impurities were removed by filtration and 78.5 g of the intermediate 1-chloroethyl ethyl carbonate (H-1) was purified by distillation.
References
[1] Synthesis, 1986, # 8, p. 627 - 632
[2] Patent: EP1437352, 2004, A1. Location in patent: Page 17
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 13, p. 5748 - 5763
[4] Patent: WO2016/207216, 2016, A1. Location in patent: Page/Page column 70
[5] Patent: CN107652239, 2018, A. Location in patent: Paragraph 0098
1-Chloroethyl ethyl carbonate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Anqing PhiChem Corporation | 0556-5209970 | salesaq@phichem.com.cn | China | 36 | 65 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Latest Price from 1-Chloroethyl ethyl carbonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-27 | 1-Chloroethyl ethyl carbonate
50893-36-2
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-06-20 | 1-Chloroethyl ethyl carbonate
50893-36-2
|
$1.00 | 1kg | 99% | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2019-07-06 | 1-Chloroethyl ethyl carbonate
50893-36-2
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 1-Chloroethyl ethyl carbonate
50893-36-2
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1-Chloroethyl ethyl carbonate
50893-36-2
- $1.00
- 99%
- Hebei Yanxi Chemical Co., Ltd.
-
- 1-Chloroethyl ethyl carbonate
50893-36-2
- $1.00
- 99%
- Career Henan Chemical Co
