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4-(Trifluoromethyl)benzyl bromide

CAS No.
402-49-3
Chemical Name:
4-(Trifluoromethyl)benzyl bromide
Synonyms
1-(BROMOMETHYL)-4-(TRIFLUOROMETHYL)BENZENE;TIMTEC-BB SBB006698;4-(Trifluoromethyl)b;4-(BROMOMETHYL)BENZOTRIFLUORIDE;P-(TRIFLUOROMETHYL)BENZYL BROMIDE;à'-bromo-à,à,à-trifluoro-p-xylene;α′-Bromo-α,α,α-trifluoro-p-xylene;4-(Trifluoromethyl)benzyl bromide;4-(Trifluoromethyl)benzylbromide98%;4-(three fluoroMethyl)benzyl broMide
CBNumber:
CB3236646
Molecular Formula:
C8H6BrF3
Molecular Weight:
239.03
MDL Number:
MFCD00000403
MOL File:
402-49-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:51

4-(Trifluoromethyl)benzyl bromide Properties

Melting point 29-33 °C(lit.)
Boiling point 65-69 °C5 mm Hg(lit.)
Density 1.546 g/mL at 25 °C(lit.)
refractive index n20/D 1.484(lit.)
Flash point 192 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Low Melting Solid
color White to light yellow
Specific Gravity 1.546
Water Solubility Insoluble in water.
Sensitive Lachrymatory
BRN 638980
InChI 1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2
InChIKey IKSNDOVDVVPSMA-UHFFFAOYSA-N
SMILES FC(F)(F)c1ccc(CBr)cc1
CAS DataBase Reference 402-49-3(CAS DataBase Reference)
FDA UNII T5YRU2P3EP
NIST Chemistry Reference 4-Trifluoromethylbenzyl bromide(402-49-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  C,Xi
Risk Statements  34
Safety Statements  26-36/37/39-45-25
RIDADR  UN 3261 8/PG 2
WGK Germany  3
8-10-19-21
Hazard Note  Corrosive/Lachrymatory
HazardClass  8
PackingGroup  III
HS Code  29039990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

4-(Trifluoromethyl)benzyl bromide price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 290564 4-(Trifluoromethyl)benzyl bromide 98% 402-49-3 1g $41.3 2026-04-30 Buy
Sigma-Aldrich 290564 4-(Trifluoromethyl)benzyl bromide 98% 402-49-3 5g $88.6 2026-04-30 Buy
TCI Chemical T1313 4-(Trifluoromethyl)benzyl Bromide >98.0%(GC) 402-49-3 5g $43 2026-04-30 Buy
TCI Chemical T1313 4-(Trifluoromethyl)benzyl Bromide >98.0%(GC) 402-49-3 25g $154 2026-04-30 Buy
TRC TRC-T790585-5G 4-(Trifluoromethyl)benzyl Bromide 402-49-3 5g $84 2026-06-03 Buy
Product number Packaging Price Buy
290564 1g $41.3 Buy
290564 5g $88.6 Buy
T1313 5g $43 Buy
T1313 25g $154 Buy
TRC-T790585-5G 5g $84 Buy

4-(Trifluoromethyl)benzyl bromide Chemical Properties,Uses,Production

Uses

4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.

Chemical Properties

white to light yellow crystalline

Uses

4-(Trifluoromethyl)benzyl bromide can be used to produce p-trifluoromethylbenzyl phenyl sulfide. It is used in medicine.

Reactions

4-(Trifluoromethyl)benzyl bromide should avoid exposure to air, moisture and light. It can react with oxidizing agents.

General Description

Vibrational characteristics of 4-(trifluoromethyl)benzylbromide have been investigated.

Hazard

4-(Trifluoromethyl)benzyl bromide is danger, it causes severe skin burns and eye damage.

100-39-0
402-49-3
Synthesis of 4-(Trifluoromethyl)benzyl bromide from Benzyl bromide

4-(Trifluoromethyl)benzyl bromide Preparation Products And Raw materials

Global( 329)Suppliers
Supplier Tel Email Country ProdList Advantage
CHANGZHOU FLUORIDE CHEMICAL CO.,LTD 0086-519-89892883 15995021858 info@fluoridechem.com China 79 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66

View Lastest Price from 4-(Trifluoromethyl)benzyl bromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(TRIFLUOROMETHYL)BENZYL BROMIDE pictures 2026-09-02 4-(TRIFLUOROMETHYL)BENZYL BROMIDE
402-49-3
$1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
4-(TRIFLUOROMETHYL)BENZYL BROMIDE pictures 2026-03-20 4-(TRIFLUOROMETHYL)BENZYL BROMIDE
402-49-3
1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
4-(Trifluoromethyl)benzyl bromide pictures 2022-02-22 4-(Trifluoromethyl)benzyl bromide
402-49-3
1KG 98.4% 100 tons Honest Joy Holdings Limited
TIMTEC-BB SBB006698 P-(TRIFLUOROMETHYL)BENZYL BROMIDE 1-Trifluoromethyl-4-(bromomethyl)benzene 4-(Trifluoromethyl)benzyl bromide, 60% in dichloromethane ALPHA'-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-P-XYLENE ALPHA-BROMO-ALPHA',ALPHA',ALPHA'-TRIFLUORO-P-XYLENE 4-(BROMOMETHYL)BENZOTRIFLUORIDE Benzene, 1-(bromomethyl)-4-(trifluoromethyl)- α′-Bromo-α,α,α-trifluoro-p-xylene à'-bromo-à,à,à-trifluoro-p-xylene 4-(Trifluoromethyl)benzyl bromide 98% 4-(Trifluoromethyl)benzylbromide98% 4-(Bromomethyl)benzotrifluoride, αμ-Bromo-α,α,α-trifluoro-p-xylene 4-(Trifluoromethyl)-1-(bromomethyl)benzene alpha'-Bromo-alpha,alpha,alpha-trifluoro-p-xylene,98% 4-(Trifluoromethyl)b 1-(Bromomethyl)-4-(trifluoromethyl)benzene, 4-(Bromomethyl)benzotrifluoride {[4-(trifluoroMethyl)phenyl]Methyl}broManuide 4-(three fluoroMethyl)benzyl broMide 4-(Bromomethyl)benzotrifluoride alpha-Bromo-alpha',alpha',alpha'-trifluoro-p-xylene 4-(TRIFLUOROMETHYL)BENZYL BROMIDE ISO 9001:2015 REACH 1-(BROMOMETHYL)-4-(TRIFLUOROMETHYL)BENZENE 4-Fluorobenzotrifluoride (p-Fluorobenzotrifluoride) 4-(Trifluoromethyl)benzyl bromide 402-49-3 Building Blocks C8 Aryl Halogenated Hydrocarbons Organic Building Blocks BENZYL HALIDE Benzyl Miscellaneous Fluoro-contained benzyl bromide series