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4-(Trifluoromethyl)benzyl bromide

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4-(Trifluoromethyl)benzyl bromide manufacturers

4-(Trifluoromethyl)benzyl bromide Basic information
Uses
Product Name:4-(Trifluoromethyl)benzyl bromide
Synonyms:TIMTEC-BB SBB006698;P-(TRIFLUOROMETHYL)BENZYL BROMIDE;1-Trifluoromethyl-4-(bromomethyl)benzene;4-(Trifluoromethyl)benzyl bromide, 60% in dichloromethane;ALPHA'-BROMO-ALPHA,ALPHA,ALPHA-TRIFLUORO-P-XYLENE;ALPHA-BROMO-ALPHA',ALPHA',ALPHA'-TRIFLUORO-P-XYLENE;4-(BROMOMETHYL)BENZOTRIFLUORIDE;Benzene, 1-(bromomethyl)-4-(trifluoromethyl)-
CAS:402-49-3
MF:C8H6BrF3
MW:239.03
EINECS:206-947-8
Product Categories:Benzyl;Miscellaneous;Fluoro-contained benzyl bromide series
Mol File:402-49-3.mol
4-(Trifluoromethyl)benzyl bromide Structure
4-(Trifluoromethyl)benzyl bromide Chemical Properties
Melting point 29-33 °C(lit.)
Boiling point 65-69 °C5 mm Hg(lit.)
density 1.546 g/mL at 25 °C(lit.)
refractive index n20/D 1.484(lit.)
Fp 192 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Low Melting Solid
color White to light yellow
Specific Gravity1.546
Water Solubility Insoluble in water.
Sensitive Lachrymatory
BRN 638980
InChI1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2
InChIKeyIKSNDOVDVVPSMA-UHFFFAOYSA-N
SMILESFC(F)(F)c1ccc(CBr)cc1
CAS DataBase Reference402-49-3(CAS DataBase Reference)
NIST Chemistry Reference4-Trifluoromethylbenzyl bromide(402-49-3)
Safety Information
Hazard Codes C,Xi
Risk Statements 34
Safety Statements 26-36/37/39-45-25
RIDADR UN 3261 8/PG 2
WGK Germany 3
8-10-19-21
Hazard Note Corrosive/Lachrymatory
HazardClass 8
PackingGroup III
HS Code 29039990
Storage Class8A - Combustible corrosive hazardous materials
Hazard ClassificationsSkin Corr. 1B
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4-(Trifluoromethyl)benzyl bromide Usage And Synthesis
Uses4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.
Chemical Propertieswhite to light yellow crystalline
Uses4-(Trifluoromethyl)benzyl bromide can be used to produce p-trifluoromethylbenzyl phenyl sulfide. It is used in medicine.
Reactions4-(Trifluoromethyl)benzyl bromide should avoid exposure to air, moisture and light. It can react with oxidizing agents.
General DescriptionVibrational characteristics of 4-(trifluoromethyl)benzylbromide have been investigated.
Hazard 4-(Trifluoromethyl)benzyl bromide is danger, it causes severe skin burns and eye damage.
4-(Trifluoromethyl)benzyl bromide Preparation Products And Raw materials
Preparation Products1-{[4-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-amine
Tag:4-(Trifluoromethyl)benzyl bromide(402-49-3) Related Product Information
3-(TRIFLUOROMETHYL)BENZYL BROMIDE 5-CHLORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE 4-FLUORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE,2-FLUORO-4-(TRIFLUOROMETHYL)BENZYL BROMIDE 2,4-BIS(TRIFLUOROMETHYL)BENZYL BROMIDE,2,4-DI(TRIFLUOROMETHYL)BENZYL BROMIDE 2-(TRIFLUOROMETHYL)BENZYL BROMIDE 3-Fluoro-4-(trifluoromethyl)benzyl bromide 4-(Trifluoromethyl)benzyl bromide 2-Fluoro-6-(trifluoromethyl)benzyl bromide 2-Fluoro-4-(trifluoromethyl)benzyl bromide 2-Fluoro-5-(trifluoromethyl)benzyl bromide 4-Fluoro-3-(trifluoromethyl)benzyl bromide 3-Fluoro-5-(trifluoromethyl)benzyl bromide 2-Chloro-5-(trifluoromethyl)benzyl bromide 3-Chloro-5-(trifluoromethyl)benzyl bromide 2-Bromo-5-(trifluoromethyl)benzyl bromide 2-Chloro-6-(trifluoromethyl)benzyl bromide 2-Methoxy-5-(trifluoromethyl)benzyl bromide 2-Methyl-5-(trifluoromethyl)benzyl bromide