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4-Methoxy-3-nitro-benzeneacetic acid methyl ester

CAS No.
34837-88-2
Chemical Name:
4-Methoxy-3-nitro-benzeneacetic acid methyl ester
Synonyms
Methyl 2-(4-methoxy-3-nitrophenyl)acetate;Methyl 2-(4-methoxy-3-nitrophenyl);4-Methoxy-3-nitro-benzeneacetic acid methyl ester;BENZENEACETIC ACID, 4-METHOXY-3-NITRO-, METHYL ESTER;2-(4-METHOXY-3-NITRO PHENYL) ACETIC ACID METHYL ETSER
CBNumber:
CB32450491
Molecular Formula:
C10H11NO5
Molecular Weight:
225.2
MDL Number:
MFCD09754963
MOL File:
34837-88-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:52

4-Methoxy-3-nitro-benzeneacetic acid methyl ester Properties

Melting point 100-102°
Boiling point 356.8±27.0 °C(Predicted)
Density 1.264±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H227
Precautionary statements  P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235
HazardClass  IRRITANT

4-Methoxy-3-nitro-benzeneacetic acid methyl ester price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 309652 Methyl 2-(4-methoxy-3-nitrophenyl)acetate 34837-88-2 250.00mg $34 2026-05-19 Buy
Matrix Scientific 309652 Methyl 2-(4-methoxy-3-nitrophenyl)acetate 34837-88-2 1.00g $95 2026-05-19 Buy
Matrix Scientific 309652 Methyl 2-(4-methoxy-3-nitrophenyl)acetate 34837-88-2 5.00g $383 2026-05-19 Buy
Matrix Scientific 046101 Methyl 2-(4-methoxy-3-nitrophenyl)acetate 34837-88-2 250.00mg $32 2026-05-18 Buy
Matrix Scientific 046101 Methyl 2-(4-methoxy-3-nitrophenyl)acetate 34837-88-2 1.00g $90 2026-05-18 Buy
Product number Packaging Price Buy
309652 250.00mg $34 Buy
309652 1.00g $95 Buy
309652 5.00g $383 Buy
046101 250.00mg $32 Buy
046101 1.00g $90 Buy

4-Methoxy-3-nitro-benzeneacetic acid methyl ester Chemical Properties, Uses, Production

Synthesis

Methyl  (4-Hydroxy-3-nitrophenyl)acetate

61873-93-6

Iodomethane

74-88-4

4-METHOXY-3-NITRO-BENZENEACETIC ACID METHYL ESTER

34837-88-2

General procedure for the synthesis of methyl 2-(4-methoxy-3-nitrophenyl)acetate from methyl 2-(4-hydroxy-3-nitrophenyl)acetate and iodomethane: To a solution of methyl 2-(4-hydroxy-3-nitrophenyl)acetate (4.87 g, 23.1 mmol) was added K2CO3 (8 g, 58 mmol) at room temperature, followed by slow addition of CH3I ( 6.6 g, 46.5 mmol). The reaction mixture was stirred at room temperature overnight. After the reaction was completed, the mixture was poured into ice water (100 mL) and extracted with CH2Cl2 (3 x 300 mL). The organic layers were combined, washed with brine, dried over Na2SO4, filtered and concentrated to give methyl 2-(4-methoxy-3-nitrophenyl)acetate (5 g, 96% yield) as a yellow solid.LCMS analysis showed an [M + H]+ of 226.0; retention time (Rt) of 1.438 min.

References

[1] Patent: WO2013/19682, 2013, A1. Location in patent: Page/Page column 106; 107

4-Methoxy-3-nitro-benzeneacetic acid methyl ester Preparation Products And Raw materials

4-Methoxy-3-nitro-benzeneacetic acid methyl ester Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 4904 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2936 56
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Jiangsu aikang biomedical research and development co., LTD 025-58859352 17714375163 qzhang@aikonchem.com China 15525 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Shandong Territorial sea Biological Technology Co., LTD 15092083467 tangfenjiushililiang@leadhigh.com.cn China 2986 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39796 58

4-Methoxy-3-nitro-benzeneacetic acid methyl ester Spectrum

BENZENEACETIC ACID, 4-METHOXY-3-NITRO-, METHYL ESTER Methyl 2-(4-methoxy-3-nitrophenyl) 2-(4-METHOXY-3-NITRO PHENYL) ACETIC ACID METHYL ETSER Methyl 2-(4-methoxy-3-nitrophenyl)acetate 4-Methoxy-3-nitro-benzeneacetic acid methyl ester 34837-88-2