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7-Methylquinazolin-4(1H)-one

CAS No.
75844-40-5
Chemical Name:
7-Methylquinazolin-4(1H)-one
Synonyms
7-Methyl-4(3H)-quinazolinone;7-methylquinazolin-4(3H)-one;7-METHYL-1H-QUINAZOLIN-4-ONE;7-Methylquinazolin-4(1H)-one;7-Methyl-4(1H)-quinazolinone;4(3H)-Quinazolinone, 7-methyl-;4(3H)-Quinazolinone, 7-methyl- >97%
CBNumber:
CB32454853
Molecular Formula:
C9H8N2O
Molecular Weight:
160.17
MDL Number:
MFCD10699397
MOL File:
75844-40-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:52

7-Methylquinazolin-4(1H)-one Properties

storage temp. Sealed in dry,Room Temperature
Appearance Light brown to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

7-Methylquinazolin-4(1H)-one price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S658324 7-METHYL-4(3H)-QUINAZOLINONE AldrichCPR 75844-40-5 1 unit $32.7 2026-04-30 Buy
Sigma-Aldrich S658324 7-METHYL-4(3H)-QUINAZOLINONE AldrichCPR 75844-40-5 250MG $29.8 2024-03-01 Buy
Biosynth ADA84440 7-Methylquinazolin-4(3H)-one 75844-40-5 5g $437.5 2026-06-04 Buy
Matrix Scientific 220324 7-Methylquinazolin-4(3H)-one 75844-40-5 1.00g $131 2026-05-18 Buy
Matrix Scientific 220324 7-Methylquinazolin-4(3H)-one 75844-40-5 5.00g $536 2026-05-18 Buy
Product number Packaging Price Buy
S658324 1 unit $32.7 Buy
S658324 250MG $29.8 Buy
ADA84440 5g $437.5 Buy
220324 1.00g $131 Buy
220324 5.00g $536 Buy

7-Methylquinazolin-4(1H)-one Chemical Properties, Uses, Production

Synthesis

2-Amino-4-methylbenzamide

39549-79-6

formamide

77287-34-4

7-METHYLQUINAZOLIN-4(1H)-ONE

75844-40-5

General procedure for the synthesis of 7-methyl-4(3H)-quinazolinone from 2-amino-4-methylbenzamide (1, 4.0 mmol) and compound (CAS: 77287-34-4, 2, 6.0 mmol): a mixture of 2-amino-4-methylbenzamide (1), formamide (2), Yb(OTf)3 (0.20 mmol, 5.0 mol%) and a mixture of homotrimethylbenzene (5.0 mL) were placed in a 20 mL Pyrex flask, the unit was equipped with a magnetic stir bar and a reflux condenser, and the reaction was carried out under argon protection. The reaction mixture was stirred at 120-165 °C (oil bath temperature) for 6 hours. After completion of the reaction, the mixture was cooled to room temperature and analyzed by GLC, GC-MS (EI) and LC-MS (ESI). After removal of homotrimethylbenzene by evaporation under vacuum, the product (3) was purified by recrystallization from methanol/hexane and/or silica gel medium pressure column chromatography (eluent: ethyl acetate/hexane = 50/50 to 100% ethyl acetate. For 3j, eluent: methanol/chloroform = 50/50). The structures of the products were confirmed by 1H NMR (400 MHz) and 13C NMR (100 MHz, DMSO-d6). The analytical and spectral data of compounds 3a-e, 3f, 3g, 3h and 3j were in agreement with literature reports. The product 3i was characterized as follows.

References

[1] Heterocycles, 2015, vol. 90, # 2, p. 857 - 865

Global Suppliers ( 74)
Supplier Tel Email Country ProdList Advantage
China Langchem Inc. 0086-21-58956006 China 7798 57
Baiyin Chengze Chemical Technology Co., Ltd. +86 943-8535351 13389336721 sales@chengzechem.com China 300 58
shanghai aokchem co., ltd 021-68712331 39130253 aokchem@gmail.com China 332 58
SynAsst Chemical. 021-60343070 China 12731 55
shanghai cooperpharm co.,LTD . +86-021-58975553 sales@cooperpharm.com China 1210 56
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
ShangHai D&B Biological Science and Technology Co.Ltd 400-008-9730,021-54359730 400-008-9730 info@chemxyz.com China 3642 60
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3769 55
NovoChemy Ltd. 86-(0)21-31261262 373522135 sales@novochemy.com China 6491 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60

View Latest Price from 7-Methylquinazolin-4(1H)-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-Methyl-4(1H)-quinazolinone pictures 2026-08-25 7-Methyl-4(1H)-quinazolinone
75844-40-5
$1.60-9.60 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

7-Methylquinazolin-4(1H)-one Spectrum

7-methylquinazolin-4(3H)-one 7-Methyl-4(3H)-quinazolinone 4(3H)-Quinazolinone, 7-methyl- >97% 7-METHYL-1H-QUINAZOLIN-4-ONE 4(3H)-Quinazolinone, 7-methyl- 7-Methyl-4(1H)-quinazolinone 7-Methylquinazolin-4(1H)-one 75844-40-5