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PLEVITREXED

PLEVITREXED Structure
PLEVITREXED structure
CAS No.
153538-08-0
Chemical Name:
PLEVITREXED
Synonyms
(Rac)-BGC9331;(Rac)-ZD 9331;(Rac)-Plevitrexed;(Rac)Plevitrexed,(Rac) Plevitrexed;2H-Tetrazole-5-butanoic acid, α-[[4-[[(3,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-2-fluorobenzoyl]amino]-
CBNumber:
CB92451263
Molecular Formula:
C26H25FN8O4
Molecular Weight:
532.53
MDL Number:
MFCD09837719
MOL File:
153538-08-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:53:02
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PLEVITREXED Properties

Density 1.44±0.1 g/cm3(Predicted)
pka 3.35±0.10(Predicted)
FDA UNII N094EYQ29D

PLEVITREXED Chemical Properties, Uses, Production

Uses

(Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331)is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. (Rac)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem.2013Jul 11;56(13):5446-55. DOI:10.1021/jm400490e

PLEVITREXED Preparation Products And Raw materials

Raw materials

Preparation Products

PLEVITREXED Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
Supplier Advantage
BOC Sciences 58
TargetMol Chemicals Inc. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
RD International Technology Co., Limited 58

153538-08-0 (PLEVITREXED) Related Search:

4-amino-2-fluoro-N-methylbenzamide PLEVITREXED Prop-2-ynyl-p-tolyl-amine 7-Methylquinazolin-4(1H)-one CB 3705
CB 30900

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(Rac)-BGC9331 (Rac)-Plevitrexed (Rac)-ZD 9331 2H-Tetrazole-5-butanoic acid, α-[[4-[[(3,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-2-fluorobenzoyl]amino]- (Rac)Plevitrexed,(Rac) Plevitrexed 153538-08-0