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4-Hydroxy-6-methylquinazoline

4-Hydroxy-6-methylquinazoline structure

CAS No.: 19181-53-4

Chemical Name:: 4-Hydroxy-6-methylquinazoline

Synonyms: BUTTPARK 51\07-11;6-methylquinazolin-4-ol;6-methyl-4-quinazolinol;6-methyl-4-quinazolinone;6-Methyl-4(3H)-quinazolinone;6-methyl-1H-quinazolin-4-one;6-methyl-3H-quinazolin-4-one;4-Hydroxy-6-methylquinazoline;4(3H)-Quinazolinone, 6-methyl-;6-Methylquinazolin-4(3H)-one98%

CBNumber:: CB6360108

Molecular Formula:: C9H8N2O

Molecular Weight:: 160.17

MDL Number:: MFCD00174855

MOL File:: 19181-53-4.mol

MSDS File:: SDS

Last updated:2026-09-12 18:54:13

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4-Hydroxy-6-methylquinazoline Properties

Melting point	238-240
Boiling point	334.6±35.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	2.06±0.20(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H302+H312+H332-H315
Precautionary statements	P301+P312-P302+P352-P305+P351+P338
Hazard Codes	Xi
Hazard Note	Irritant
HS Code	2933399990

4-Hydroxy-6-methylquinazoline price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR2839	4-Hydroxy-6-methylquinazoline 97%	19181-53-4	250mg	$21	2026-06-04	Buy
Apolloscientific	OR11427	6-Methylquinazolin-4(3H)-one 98%	19181-53-4	1g	$32	2026-06-04	Buy
Matrix Scientific	126524	6-Methylquinazolin-4-ol	19181-53-4	1.00g	$144	2026-05-18	Buy
Matrix Scientific	126524	6-Methylquinazolin-4-ol	19181-53-4	5.00g	$432	2026-05-18	Buy
Matrix Scientific	126524	6-Methylquinazolin-4-ol	19181-53-4	10.00g	$684	2026-05-18	Buy

Product number	Packaging	Price	Buy
OR2839	250mg	$21	Buy
OR11427	1g	$32	Buy
126524	1.00g	$144	Buy
126524	5.00g	$432	Buy
126524	10.00g	$684	Buy

4-Hydroxy-6-methylquinazoline Chemical Properties, Uses, Production

Synthesis

40545-33-3

149-73-5

19181-53-4

Concentrated hydrochloric acid (4.16 mL, 49.9 mmol) was slowly added to a mixed solution containing commercially available 2-amino-5-methylbenzamide (5.00 g, 33.3 mmol) and trimethyl orthoformate (51.0 mL, 466 mmol) at 0 °C. The reaction mixture was stirred continuously for 2 hours at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue obtained was diluted with distilled water and neutralized with 2 M aqueous sodium hydroxide solution to neutral. Subsequently, the precipitated solid product was collected by filtration and washed sequentially with distilled water, methanol, and ether to finally obtain 6-methyl-4-hydroxyquinazoline (15) as a white powdery solid (4.33 g, 81% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 2.44 (3H, s), 7.57 (1H, d, J = 8.4 Hz), 7.62-7.66 (1H, m), 7.91-7.93 (1H, m), 8.03 (1H, s), 12.2 (1H, bs).

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 19, p. 5487 - 5505
[2] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 4, p. 545 - 548
[3] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 3, p. 383 - 391

4-Hydroxy-6-methylquinazoline Preparation Products And Raw materials

Raw materials

2-Amino-5-methylbenzoic acid 2-Iodo-5-methylbenzoic acid Methanol 2-Amino-5-methylbenzamide Formamidine hydrochloride

formamide Trimethoxymethane Hydrochloric acid

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Preparation Products

4-Hydroxy-6-methylquinazoline Suppliers

Global Suppliers ( 105)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai yirong biology science and technology co., ltd	18049974220	3060526242@qq.com	China	999	60
Chiba Pharmaceutical Science and technology Co, Ltd.	0531-81313138 13066006660	chibapharm@foxmail.com	China	3996	55
Shanghai Jian Chao Chemical Technology Co., Ltd.	150-2103-5486 18017383231	983544897@qq.com	China	9335	55
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	18201	56
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Adamas Reagent, Ltd.	59
Accela ChemBio Co.,Ltd.	64
Shanghai yirong biology science and technology co., ltd	60
Chiba Pharmaceutical Science and technology Co, Ltd.	55
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
9ding chemical ( Shanghai) Limited	56
Bide Pharmatech Ltd.	60

View Latest Price from 4-Hydroxy-6-methylquinazoline manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	4-HYDROXY-6-METHYLQUINAZOLINE 19181-53-4	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
	2019-07-06	4-HYDROXY-6-METHYLQUINAZOLINE 19181-53-4	$3.00	1KG	90%-99.9%	1000kg	Career Henan Chemical Co

4-HYDROXY-6-METHYLQUINAZOLINE
19181-53-4
$1.10
99.00%
Dideu Industries Group Limited

4-HYDROXY-6-METHYLQUINAZOLINE
19181-53-4
$3.00
90%-99.9%
Career Henan Chemical Co

4-Hydroxy-6-methylquinazoline Spectrum

4-HYDROXY-6-METHYLQUINAZOLINE(19181-53-4)¹HNMR

19181-53-4 (4-Hydroxy-6-methylquinazoline) Related Search:

NU1025 8-Chloro-2-methylquinazolin-4(3H)-one Raltitrexed 2,6-Dimethylquinazolin-4(3H)-one 2-Amino-6-methyl-4(3H)-quinazolone

2-Methyl-4(3H)-quinazolinone Nolatrexed dihydrochloride 4-Hydroxy-6-methylquinazoline 8-Methyl-4-quinazolone 6-Quinazolinecarboxylic acid, 3,4-dihydro-3-(2-chlorophenyl)-5,7-dimet hyl-2-((((methylamino)carbonyl)oxy)methyl)-4-oxo-, ethyl ester

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BUTTPARK 51\07-11 3,4-Dihydro-6-methyl-4-oxoquinazoline 3,4-Dihydro-6-methyl-4-oxoquinazoline 98% 4-Hydroxy-6-methylquinazoline 97% 4-Hydroxy-6-methylquinazoline97% 6-methyl-4-quinazolinone 6-methylquinazolin-4-ol 6-Methylquinazolin-4(3H)-one 98% 6-Methyl-4(3H)-quinazolinone 6-Methylquinazolin-4-ol, 6-Methylquinazolin-4(3H)-one 6-Methylquinazolin-4(3H)-one98% 6-methyl-1H-quinazolin-4-one 4(3H)-Quinazolinone, 6-methyl- 4-HYDROXY-6-METHYLQUINAZOLINE ISO 9001：2015 REACH 6-methyl-3H-quinazolin-4-one 6-methyl-4-quinazolinol 4-Hydroxy-6-methylquinazoline 19181-53-4 blocks Heterocycles Quinolines