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ChemicalBook >> CAS DataBase List >>6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Structure
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one structure
CAS No.
1016636-76-2
Chemical Name:
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
Synonyms
6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one;6-broMo-2-chloro-8-cyclopentyl-5-;6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one;PALBOCI;PALBOCICLIB-PB3;Palbociclib-015;Palbociclib nuclear;Pabucilib impurity 8;Palbociclib Impurity I;Palbociclib Intermediate 3
CBNumber:
CB32554175
Molecular Formula:
C13H13BrClN3O
Molecular Weight:
342.62
MDL Number:
MFCD13181208
MOL File:
1016636-76-2.mol
MSDS File:
SDS
Last updated:2025-09-18 19:10:02
Request For Quotation

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Properties

Melting point 190-192°C
Boiling point 468.4±45.0 °C(Predicted)
Density 1.645±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka -0.61±0.20(Predicted)
form Solid
color White
InChI InChI=1S/C13H13BrClN3O/c1-7-9-6-16-13(15)17-11(9)18(12(19)10(7)14)8-4-2-3-5-8/h6,8H,2-5H2,1H3
InChIKey HJQCAEDIUJXGCQ-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C2C(C)=C(Br)C(=O)N(C3CCCC3)C2=N1
FDA UNII 6SDD8U5F6G
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN2811

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B682195 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one 1016636-76-2 100mg $80 2021-12-16 Buy
Matrix Scientific 096533 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one 95+% 1016636-76-2 250mg $742 2021-12-16 Buy
AK Scientific J52040 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2 1g $10 2021-12-16 Buy
Matrix Scientific 096533 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one 95+% 1016636-76-2 1g $1647 2021-12-16 Buy
AK Scientific J52040 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2 10g $42 2021-12-16 Buy
Product number Packaging Price Buy
B682195 100mg $80 Buy
096533 250mg $742 Buy
J52040 1g $10 Buy
096533 1g $1647 Buy
J52040 10g $42 Buy

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemical Properties,Uses,Production

Use

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.

Description

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one is a pharmaceutical intermediate that can be used to synthesize Palbociclib, an inhibitor of cyclin-dependent kinases (CDKs) 4 and 6 for the treatment of breast cancer.

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Suppliers

Global( 504)Suppliers
Supplier Tel Email Country ProdList Advantage
Senova Technology Co. Ltd.
+86-0755-86703119 +8618503098836 info@senovatech.com China 351 58
AstaTech(Chengdu) Biopharmaceutical Corp.
+86-02882666559 +86-15884417729 gjpu@astatech.com.cn China 308 58
ChemExpress
+86-19370970350 +86-021-58950125 info@chemexpress.com China 788 58
Unibest Industrial Co.,Ltd.
+86-0574-27855777 +8618758850676 info@unibestcn.com China 251 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58
Hebei Mujin Biotechnology Co.,Ltd 		+8613288715578 sales@hbmojin.com China 12248 58
Shanghai Joiny Pharmaceutical Co.,LTD 		+86-13681955282 gyd@joiny-pharma.com China 314 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1014 58
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD. 		+86-531-88625728 +86-15806417970 sales@boyuanpharm.com China 272 58
hebei hongtan Biotechnology Co., Ltd 		+852-6619 3215 +86-17731935328 sales03@chemcn.cn China 970 58
Supplier Advantage
Senova Technology Co. Ltd.
58
AstaTech(Chengdu) Biopharmaceutical Corp.
58
ChemExpress
58
Unibest Industrial Co.,Ltd.
58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
58
Hebei Mujin Biotechnology Co.,Ltd 		58
Shanghai Joiny Pharmaceutical Co.,LTD 		58
Hangzhou ICH Biofarm Co., Ltd 		58
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD. 		58
hebei hongtan Biotechnology Co., Ltd 		58

View Lastest Price from 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one pictures 2025-10-08 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
1016636-76-2
 US $14.00 / ASSAYS 1ASSAYS 99% 20mt Jinan Finer Chemical Co., Ltd
6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one pictures 2025-09-29 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
1016636-76-2
 US $0.00-0.00 / Kg/Drum 1KG 99%min 100kg WUHAN FORTUNA CHEMICAL CO., LTD
Palbociclib Impurity 8 pictures 2025-09-25 Palbociclib Impurity 8
1016636-76-2
 US $0.00-0.00 / mg 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Spectrum

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one(1016636-76-2)1HNMR

1016636-76-2(6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one)Related Search:

6-broMo-4,4-diMethyl-3,4-dihydronaphthalen-1(2H)-one tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Palbociclib Impurity N Palbociclib Impurity D
5-(piperazin-1-yl)pyridin-2-aMine Palbociclib-012 5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine 6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one Ezetimibe
(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE 5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde pyridine-3-sulfonyl chloride 4-[[(4-Fluorophenyl)imino]methyl]-phenol Flupirtine maleate
5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one sacubitril 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)-

1of4

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-on 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-broMo-2-chloro-8-cyclopentyl-5-Methyl- Palbociclib-015 6-bromo-2-chloro-8-cyclopentyl-5-methylpyridino[2,3-d]pyrimidin-7(8H)-one 6-broMo-2-chloro-8-cyclopentyl-5- 6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one PALBOCICLIB-PB3 6-bromo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one(For Palbociclib) 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one PALBOCI 6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one Palbociclib Intermediate 3 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one(1016636-76-2) Palbociclib Impurity I 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2 -broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one ISO 9001：2015 REACH 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido {2,3} pyrimidin-7-(8H)-one 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H) 6-bromo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 6- 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidi... Palbociclib nuclear 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(9H)-one 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido {2,3} pyrimidine-7-(8H)-one 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3- Pabucilib impurity 8 1016636-76-26-Bromo-2-chloro-8-cyclopentyl-5-methyl-pyrido[2,3-D]pyrimidin-7(8H)-one 1016636-76-2 1016636-76-3 2174002-19-8 Palbociclib PD 0332991 Anticancer 1016636-76-2