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TPPB

CAS No.
497259-23-1
Chemical Name:
TPPB
Synonyms
TPPB;CS-2585;TPPB, 10 mM in DMSO;α-Amyloid Precursor Protein Modulator;alpha-AMyloid Precursor Protein Modulator;PKC,Protein kinase C,TPPB,inhibit,Inhibitor;α-Amyloid Precursor Protein Modulator(TPPB);α-Amyloid Precursor Protein Modulator, >=98%;TPPB/ α-Amyloid Precursor Protein Modulator;(2E,4E)-N-[(2S,5R)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1-benzazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide
CBNumber:
CB32602544
Molecular Formula:
C27H30F3N3O3
Molecular Weight:
501.54
MDL Number:
MFCD09037558
MOL File:
497259-23-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:08:26

TPPB Properties

Boiling point 728.8±60.0 °C(Predicted)
Density 1.229
storage temp. Store at -20°C
solubility 25.08mg/mL in DMSO
pka 12.76±0.60(Predicted)
form Solid
color Light yellow to yellow
InChIKey WOLVEMPZUIFSII-IHHOKICGSA-N
SMILES C(NC1=CC=C2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)CC2=C1)(=O)/C=C/C=C/C1=CC=C(C(F)(F)F)C=C1
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
WGK Germany  WGK 1
Storage Class 11 - Combustible Solids

TPPB price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 565740 α-Amyloid Precursor Protein Modulator A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 497259-23-1 1 mg $385 2026-04-30 Buy
Biosynth FH104242 TPPB 497259-23-1 1mg $171.88 2026-06-04 Buy
Biosynth FH104242 TPPB 497259-23-1 5mg $687.5 2026-06-04 Buy
Biosynth FH104242 TPPB 497259-23-1 10mg $1031.3 2026-06-04 Buy
ChemScene CS-7939 TPPB 99.92% 497259-23-1 1mg $217 2026-06-04 Buy
Product number Packaging Price Buy
565740 1 mg $385 Buy
FH104242 1mg $171.88 Buy
FH104242 5mg $687.5 Buy
FH104242 10mg $1031.3 Buy
CS-7939 1mg $217 Buy

TPPB Chemical Properties, Uses, Production

Uses

TPPB is a protein kinase C (PKC) activator.

Biological Activity

Cell permeable: yes', 'Primary Target
PKC', 'Product does not compete with ATP.', 'Reversible: no', 'Target Ki: 11.9 nM for activating PKCα

storage

Store at -20°C

TPPB Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 106)
Supplier Tel Email Country ProdList Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 964 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Chengdu NoVi Biotechnology Co., Ltd. 028-81458053 novibiotech@163.com sales@novi-biotech.com China 226 55
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4859 55
Twochem Co.Ltd 021-021-58111628 15800915896 sales@twochem.com China 303 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Lancrix Chemicals 86-21-50817262 sales@lancrix.com China 1498 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62

View Latest Price from TPPB manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TPPB pictures 2026-02-02 TPPB
497259-23-1
10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
  • TPPB pictures
  • TPPB
    497259-23-1
  • 99%HPLC
  • Shaanxi Dideu Medichem Co. Ltd
TPPB (2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide alpha-AMyloid Precursor Protein Modulator TPPB/ α-Amyloid Precursor Protein Modulator α-Amyloid Precursor Protein Modulator, >=98% (2E,4E)-N-((2S,5S)-5-(hydroxymethyl)-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydrobenzo[e][1,4]diazocin-8-yl)-5-(4-(trifluoromethyl)phenyl)penta-2,4-dienamide (2E,4E)-N-[(2S,5R)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1-benzazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide CS-2585 2,4-Pentadienamide, N-[(2S,5S)-1,2,3,4,5,6-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-, (2E,4E)- α-Amyloid Precursor Protein Modulator PKC,Protein kinase C,TPPB,inhibit,Inhibitor (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide α-Amyloid Precursor Protein Modulator(TPPB) (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-(propan-2-yl)-1,2,3,4,5,6-hexahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide TPPB, 10 mM in DMSO 497259-23-1 C27H30F3N3O3 C28H31F3N2O3 API