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2-Chloro-5-nitro-benzamine

2-Chloro-5-nitro-benzamine Structure
2-Chloro-5-nitro-benzamine structure
CAS No.
6283-25-6
Chemical Name:
2-Chloro-5-nitro-benzamine
Synonyms
2-CHLORO-5-NITROANILINE;oro-5-nitroaniL;Reaxys ID: 2208878;TIMTEC-BB SBB003829;2-Chlor-5-nitroanilin;6-Chloro-3-nitroaniline;6-chloro-3-nitro-anilin;3-Nitro-6-chloroaniline;5-NITRO-2-CHLOROANILINE;2-chloro-5-nitro-anilin
CBNumber:
CB3269848
Molecular Formula:
C6H5ClN2O2
Molecular Weight:
172.57
MDL Number:
MFCD00007668
MOL File:
6283-25-6.mol
MSDS File:
SDS
Last updated:2026-05-28 01:10:12
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2-Chloro-5-nitro-benzamine Properties

Melting point 118-120 °C(lit.)
Boiling point 200°C (rough estimate)
Density 1.5610 (rough estimate)
refractive index 1.5870 (estimate)
Flash point 191°C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka 0.60±0.10(Predicted)
color Light yellow to Amber to Dark green
BRN 2208878
Henry's Law Constant 1.8×103 mol/(m3Pa) at 25℃, HSDB (2015)
InChI InChI=1S/C6H5ClN2O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,8H2
InChIKey KWIXNFOTNVKIGM-UHFFFAOYSA-N
SMILES C1(N)=CC([N+]([O-])=O)=CC=C1Cl
CAS DataBase Reference 6283-25-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII PO198891S5
NIST Chemistry Reference Benzenamine, 2-chloro-5-nitro-(6283-25-6)
EPA Substance Registry System 2-Chloro-5-nitroaniline (6283-25-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H300-H310-H330-H373-H411-H401-H300+H310+H330-H315-H319
Precautionary statements  P262-P270-P271-P301+P310+P330-P302+P352+P310+P361+P364-P304+P340+P310-P305+P351+P338+P337+P313-P314-P391-P403+P233-P405-P501-P260-P264-P273-P280-P284-P301+P310-P301+P310a-P304+P340-P320-P330-P501a
Hazard Codes  T+,N
Risk Statements  26/27/28-33-51/53-50/53
Safety Statements  28-36/37-45-61-28A-60-13
RIDADR  UN 2237 6.1/PG 3
WGK Germany  3
RTECS  BX1500000
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29215900
Hazardous Substances Data 6283-25-6(Hazardous Substances Data)
NFPA 704
1
1 0

2-Chloro-5-nitro-benzamine price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C0403 2-Chloro-5-nitroaniline >98.0%(GC) 6283-25-6 25g $21 2026-04-30 Buy
TCI Chemical C0403 2-Chloro-5-nitroaniline >98.0%(GC) 6283-25-6 500g $106 2026-04-30 Buy
Apolloscientific OR322053 2-Chloro-5-nitroaniline >98% 6283-25-6 100g $32 2026-06-04 Buy
Apolloscientific OR322053 2-Chloro-5-nitroaniline >98% 6283-25-6 500g $81 2026-06-04 Buy
Activate Scientific AS40216 2-Chloro-5-nitro aniline 95% 6283-25-6 5g $18 2026-06-04 Buy
Product number Packaging Price Buy
C0403 25g $21 Buy
C0403 500g $106 Buy
OR322053 100g $32 Buy
OR322053 500g $81 Buy
AS40216 5g $18 Buy

2-Chloro-5-nitro-benzamine Chemical Properties, Uses, Production

Chemical Properties

yellow powder

Uses

2-Chloro-5-nitroaniline is a chemical reagent used in the synthesis anti-inflammatory 1,1-dioxido propenone derivatives.

Synthesis

2-Bromo-5-nitroaniline

10403-47-1

2-Chloro-5-nitro-benzamine

6283-25-6

General procedure: Catalyst 1 (10 mol%), 2-bromo-5-nitroaniline (1.0 mmol), tetramethylammonium chloride (Me4NCl, 2.0 mmol) and ethanol (EtOH, 2.0 mL) were sequentially added to the Schlenk tube under nitrogen protection. The Schlenk tube was sealed using a polytetrafluoroethylene (Teflon) valve and the reaction mixture was stirred at 100 °C for the reaction time referred to in Table 2 (the reaction process was monitored by gas chromatography (GC)). Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 10/1) to give 2-chloro-5-nitroaniline. The product yield was determined by high-resolution gas chromatography-mass spectrometry (GC-MS) analysis, and the structure was confirmed by comparing its physical properties and spectral data with known compounds.

References

[1] Applied Catalysis A: General, 2014, vol. 472, p. 178 - 183

2-Chloro-5-nitro-benzamine Preparation Products And Raw materials

Raw materials

2-Bromo-5-nitroaniline Ethanol

Preparation Products

5-Amino-2-methylbenzothiazole 4-chloro-3-(pyridin-2-yl)aniline 5-(2-Chloro-5-nitro-phenyl)-furan-2-carboxylic acid 6-Nitro-2H-benzo[b][1,4]thiazin-3(4H)-one

2-Chloro-5-nitro-benzamine Suppliers

Global Suppliers ( 332)
Supplier Tel Email Country ProdList Advantage
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 13396369453 18678026865 sdfantai@163.com China 904 58
Wuxi Renyi New Materials Technology Co., Ltd 13306222239 wangmeili@renyiam.com China 558 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Supplier Advantage
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. 58
Wuxi Renyi New Materials Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Beijing dtftchem Technology Co., Ltd. 62
Energy Chemical 61
Beijing Ouhe Technology Co., Ltd 60

View Latest Price from 2-Chloro-5-nitro-benzamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-nitro-benzamine pictures 2026-08-20 2-Chloro-5-nitro-benzamine
6283-25-6
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-Chloro-5-nitro-benzamine pictures 2023-03-13 2-Chloro-5-nitro-benzamine
6283-25-6
 1kg 98%Min 1000kg LY Global chemicals co.,ltd .
2-Chloro-5-nitroaniline pictures 2021-01-27 2-Chloro-5-nitroaniline
6283-25-6
 1T 99% 300 tons/year YANGZHOU SHUANGDING CHEM CO., LTD

2-Chloro-5-nitro-benzamine Spectrum

2-Chloro-5-nitro-benzamine(6283-25-6)MS2-Chloro-5-nitro-benzamine(6283-25-6)1HNMR2-Chloro-5-nitro-benzamine(6283-25-6)13CNMR2-Chloro-5-nitro-benzamine(6283-25-6)IR12-Chloro-5-nitro-benzamine(6283-25-6)IR2

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