ChemicalBook >> CAS DataBase List >>3-Hydroxy-4-methoxybenzoic acid

3-Hydroxy-4-methoxybenzoic acid

CAS No.
645-08-9
Chemical Name:
3-Hydroxy-4-methoxybenzoic acid
Synonyms
ISOVANILLIC ACID;AKOS 220-48;Thenblueacid;Isovanillic aci;Diosmin Impurity A;Diosmin Impurity 1;acideisovanillique;IsovanillicAcid>RARECHEM AL BE 0068;Diosmin Impurity 10
CBNumber:
CB3303201
Molecular Formula:
C8H8O4
Molecular Weight:
168.15
MDL Number:
MFCD00002507
MOL File:
645-08-9.mol
MSDS File:
SDS
Last updated:2026-04-09 22:57:55
Product description Number Pack Size Price
Isovanillic Acid >98.0%(HPLC)(T) I0295 10g $79
Isovanillic Acid >98.0%(HPLC)(T) I0295 25g $161
Isovanillic Acid >98.0%(HPLC)(T) I0295 5g $51
3-Hydroxy-4-methoxybenzoicacid H972638 1g $55
3-Hydroxy-4-methoxybenzoic acid 063756 25g $72
More product size

3-Hydroxy-4-methoxybenzoic acid Properties

Melting point 250-253 °C(lit.)
Boiling point 257.07°C (rough estimate)
Density 1.3037 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Inert atmosphere,Room Temperature
form Powder
pka 4.35±0.10(Predicted)
color Beige to gray-brown
BRN 2208365
InChI 1S/C8H8O4/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,9H,1H3,(H,10,11)
InChIKey LBKFGYZQBSGRHY-UHFFFAOYSA-N
SMILES COc1ccc(cc1O)C(O)=O
LogP 1.350 (est)
CAS DataBase Reference 645-08-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII A8D1DUX2PR
NIST Chemistry Reference 3-Hydroxy-4-methoxybenzoic acid(645-08-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  BZ4850000
HazardClass  IRRITANT
HS Code  29189900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

3-Hydroxy-4-methoxybenzoic acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical I0295 Isovanillic Acid >98.0%(HPLC)(T) 645-08-9 10g $79 2021-12-16 Buy
TCI Chemical I0295 Isovanillic Acid >98.0%(HPLC)(T) 645-08-9 25g $161 2026-03-19 Buy
TCI Chemical I0295 Isovanillic Acid >98.0%(HPLC)(T) 645-08-9 5g $51 2026-03-19 Buy
TRC H972638 3-Hydroxy-4-methoxybenzoicacid 645-08-9 1g $55 2021-12-16 Buy
Matrix Scientific 063756 3-Hydroxy-4-methoxybenzoic acid 645-08-9 25g $72 2021-12-16 Buy
Product number Packaging Price Buy
I0295 10g $79 Buy
I0295 25g $161 Buy
I0295 5g $51 Buy
H972638 1g $55 Buy
063756 25g $72 Buy

3-Hydroxy-4-methoxybenzoic acid Chemical Properties,Uses,Production

Chemical Properties

beige to grey-brown powder

Uses

Isovanillic acid has been used in the synthesis of opiate alkaloid precursor, dihydrothebainone.

Definition

ChEBI: A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3.

General Description

Rate of oxidation of isovanillic acid by washed cells of Pseudomonas putida has been reported.

621-59-0
645-08-9
Synthesis of 3-Hydroxy-4-methoxybenzoic acid from Isovanillin

3-Hydroxy-4-methoxybenzoic acid Preparation Products And Raw materials

Global( 425)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29825 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58

View Lastest Price from 3-Hydroxy-4-methoxybenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isovanillic acid pictures 2026-04-09 Isovanillic acid
645-08-9
US $0.00 / removed 98.31% 10g TargetMol Chemicals Inc.
3-Hydroxy-4-methoxybenzoic acid pictures 2026-03-20 3-Hydroxy-4-methoxybenzoic acid
645-08-9
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
3-Hydroxy-4-methoxybenzoic acid pictures 2025-04-15 3-Hydroxy-4-methoxybenzoic acid
645-08-9
US $200.00-95.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
AKOS 220-48 4-METHOXY-3-HYDROXYBENZOIC ACID 3-HYDROXYANISIC ACID 3-HYDROXY-4-METHOXYBENZOIC ACID ISOVANILLIC ACID 3-hydroxy-4-methoxy-benzoicaci RARECHEM AL BE 0068 Isovanillic aci 4-Carboxy-2-hydroxyanisole, Isovanillic acid, 2-Methoxy-5-carboxyphenol, 5-Carboxyguaiacol, 3-Hydroxy-p-anisic acid Thenblueacid Diosmin Impurity A Diosmin Impurity 10 Diosmin Impurity 1 3-hydroxy-p-anisicaci Acide isovanillique acideisovanillique Benzoic acid, 3-hydroxy-4-methoxy- p-Anisic acid, 3-hydroxy- ISOVANILLIC ACID (3-HYDROXY-4-METHOXYBENZOIC ACID) 3-Hydroxy-4-methoxybenzoic acid, 97+% 5-Carboxy-2-methoxyphenol 3-Hydroxy-4-methoxybenzoic acid,99% 3-hydroxy-p-anisic acid 3-Hydroxy-4-Methoxybenzoic 3-Hydroxy-4-Methoxybenzoic acid, 99% 5GR 4-Carboxy-2-hydroxyanisole, Isovanillic acid IsovanillicAcid> Isovanillic acid,97% Diossmin impurity 19 Isovanillic acid, 10 mM in DMSO 645-08-9 HOC6H3OCH3CO2H Organic Building Blocks Building Blocks C8 Carbonyl Compounds Carboxylic Acids sy Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts BenzoicAcidDerivative Acids and Derivatives Alcohols and Derivatives API intermediates