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ChemicalBook >> CAS DataBase List >>3,5-Dibromo-2-pyridylamine

3,5-Dibromo-2-pyridylamine

3,5-Dibromo-2-pyridylamine Structure
3,5-Dibromo-2-pyridylamine structure
CAS No.
35486-42-1
Chemical Name:
3,5-Dibromo-2-pyridylamine
Synonyms
3,5-DIBROMOPYRIDIN-2-AMINE;2-AMINO-3,5-DIBROMOPYRIDINE;AKOS BB-8249;AURORA KA-520;ASISCHEM X26831;AKOS BBS-00001351;TIMTEC-BB SBB000910;2-Amino-3,5-dibromo;Xylulose Impurity 2;SALOR-INT L495980-1EA
CBNumber:
CB3303872
Molecular Formula:
C5H4Br2N2
Molecular Weight:
251.91
MDL Number:
MFCD00038041
MOL File:
35486-42-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:30:00
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3,5-Dibromo-2-pyridylamine Properties

Melting point 104-105 °C (lit.)
Boiling point 253.9±35.0 °C(Predicted)
Density 2.147±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 1.89±0.49(Predicted)
Appearance Light yellow to yellow Solid
BRN 119390
InChI InChI=1S/C5H4Br2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)
InChIKey WJMJWMSWJSACSN-UHFFFAOYSA-N
SMILES C1(N)=NC=C(Br)C=C1Br
CAS DataBase Reference 35486-42-1(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P304+P340-P405-P501a
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

3,5-Dibromo-2-pyridylamine price More Price(74)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A1588 2-Amino-3,5-dibromopyridine >98.0%(GC) 35486-42-1 5g $18 2026-04-30 Buy
TCI Chemical A1588 2-Amino-3,5-dibromopyridine >98.0%(GC) 35486-42-1 25g $28 2026-04-30 Buy
Usbiological 259975 2-Amino-3,5-dibromopyridine Asreported 35486-42-1 25g $335 2026-06-03 Buy
Usbiological 259975 2-Amino-3,5-dibromopyridine Asreported 35486-42-1 50g $456 2026-06-03 Buy
Usbiological 259975 2-Amino-3,5-dibromopyridine Asreported 35486-42-1 100g $611 2026-06-03 Buy
Product number Packaging Price Buy
A1588 5g $18 Buy
A1588 25g $28 Buy
259975 25g $335 Buy
259975 50g $456 Buy
259975 100g $611 Buy

3,5-Dibromo-2-pyridylamine Chemical Properties, Uses, Production

Chemical Properties

yellow to brown fine crystalline powder

Uses

The synthesis of 2-amino-3,5-dibromopyridine complexes and their analysis by single crystal X-ray diffraction has been studied.

General Description

The synthesis of 2-amino-3,5-dibromopyridine complexes and their analysis by single crystal X-ray diffraction has been studied.

Synthesis

2-Aminopyridine

504-29-0

2-Amino-5-bromopyridine

1072-97-5

3,5-Dibromo-2-pyridylamine

35486-42-1

General procedure for the synthesis of 2-amino-5-bromopyridine and 2-amino-3,5-dibromopyridine from 2-aminopyridine: 28.2 g (0.3 mol) of 2-aminopyridine was dissolved in 50 ml of acetic acid. The solution is cooled to below 20°C by means of an ice bath and 48 g (15.4 ml, 0.3 mol) of bromine dissolved in 30 ml of acetic acid is added slowly and dropwise over a period of 1 h under vigorous stirring. The temperature was maintained below 20°C at the beginning of the reaction. Upon addition of half of the bromine solution, the reaction temperature was raised to 50°C to promote precipitation of 2-amino-5-bromopyridine hydrobromide. At 50°C, the hydrobromide typically begins to crystallize when about three-quarters of the bromine is added. After completion of the bromine addition, stirring of the reaction mixture was continued for 1 hour, followed by dilution with 75 mL of water to dissolve the hydrobromide. The reaction solution is transferred to a 500 ml beaker and neutralized by the slow addition of 120 ml of 40% sodium hydroxide solution under stirring and cooling conditions. Filtration and drying gave a crude product of 2-amino-5-bromopyridine containing a small amount of 2-amino-3,5-dibromopyridine. The 2-amino-3,5-dibromopyridine was removed from the crude product by washing with 500 ml of hot petroleum ether in three passes. The final yield of 2-amino-5-bromopyridine was 32-34.7 g (62-67% yield) with a melting point of 134°C (literature value: 132-135°C).

Purification Methods

Steam distil it and recrystallise it from aqueous EtOH or pet ether. [Beilstein 22 H 431, 22 II 333, 22 III/IV 4041.]

References

[1] Synthetic Communications, 1986, vol. 16, # 13, p. 1641 - 1646
[2] Canadian Journal of Chemistry, 2005, vol. 83, # 2, p. 146 - 149
[3] Synthesis (Germany), 2015, vol. 47, # 20, p. 3169 - 3178
[4] Journal of Organic Chemistry, 1983, vol. 48, # 7, p. 1064 - 1069
[5] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 7, p. 2455 - 2478

3,5-Dibromo-2-pyridylamine Preparation Products And Raw materials

Raw materials

5-Bromo-2-nitropyridine 2-Amino-5-bromopyridine 3-Bromo-2-pyridinamine 2-Aminopyridine

Preparation Products

5,6,7,8-Tetrahydro-1H-pyrido[2,3-b]indole

3,5-Dibromo-2-pyridylamine Suppliers

Global Suppliers ( 419)
Supplier Tel Email Country ProdList Advantage
Suzhou Wenzhi Biotechnology Co., Ltd. 13262848185 20840032@qq.com China 161 58
Changzhou Yuxiang Chemical Co., Ltd 13809076511 344679571@qq.com China 311 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Liaoning Tianhua Chemical Co., Ltd. 0418-6530555 2855550 China 338 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Supplier Advantage
Suzhou Wenzhi Biotechnology Co., Ltd. 58
Changzhou Yuxiang Chemical Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Liaoning Tianhua Chemical Co., Ltd. 69
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Wuhan Chemwish Technology Co., Ltd 56

View Latest Price from 3,5-Dibromo-2-pyridylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-dibromopyridin-2-amine pictures 2026-09-02 3,5-dibromopyridin-2-amine
35486-42-1
 $8.00 1KG 99% Henan Fengda Chemical Co., Ltd
3,5-Dibromo-2-pyridylamine pictures 2026-08-20 3,5-Dibromo-2-pyridylamine
35486-42-1
 $1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
3,5-Dibromo-2-pyridylamine pictures 2026-06-30 3,5-Dibromo-2-pyridylamine
35486-42-1
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

3,5-Dibromo-2-pyridylamine Spectrum

3,5-Dibromo-2-pyridylamine(35486-42-1)MS3,5-Dibromo-2-pyridylamine(35486-42-1)1HNMR3,5-Dibromo-2-pyridylamine(35486-42-1)13CNMR3,5-Dibromo-2-pyridylamine(35486-42-1)IR13,5-Dibromo-2-pyridylamine(35486-42-1)IR23,5-Dibromo-2-pyridylamine(35486-42-1)Raman

35486-42-1 (3,5-Dibromo-2-pyridylamine) Related Search:

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2-Amino-3,5-dibromo pyridine ,99% 3,5-Dibromo-2-pyridinamine 2-amino-3,5-dibormopyridine 2-Amino-3,5-dibromopyridine,97% 3,5-Dibromo-2-aminopyridine 2-Amino-3,5-dibromopyridine  2-Amino-3,5-dibromo pyrdine TIMTEC-BB SBB000910 SALOR-INT L495980-1EA ASISCHEM X26831 AURORA KA-520 LABOTEST-BB LT00000217 2-Amino-3,5-dibromopyridine 97% AKOS BBS-00001351 AKOS BB-8249 2-PYRIDINAMINE, 3,5-DIBROMO- 2-amino-3,5-dibromopyridinehydrate 2-Amino-3,5-dibromo 3,5-dibromo-2-pyridylamine 3,5-Dibromo-pyridin-2-ylamine 3,5-Dibrom-2-pyridylamin 2-Amino-3,5-dibromopyridine > 3,5-Dibromo-2-pyridylamine ISO 9001：2015 REACH Palbociclib Impurity 90 2-Amino 5-bromopyrdiene Xylulose Impurity 2 2-Amino-3,5-dibromopyridine, 98% 2-AMINO-3,5-DIBROMOPYRIDINE 3,5-DIBROMOPYRIDIN-2-AMINE 35486-42-1 C5H4N2Br2 C5H4Br2NxH2O C5H4Br2NH2O AMINE Halopyridines Bromopyridines Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Pyridines, Pyrimidines, Purines and Pteredines Pyridine Amino-pyridine series Bromopyridines Halopyridines C5Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks blocks Bromides Pyridines