ChemicalBook >> CAS DataBase List >>Phlorizin dihydrate
Phlorizin dihydrate
- CAS No.
- 7061-54-3
- Chemical Name:
- Phlorizin dihydrate
- Synonyms
- PHLORIDZIN;PHLORIDZIN(RG);TIMTEC-BB SBB005924;Phlorizin dihydrate;Phloridzin dihydrate 99%;phloridzin from apple wood;PHLORETIN-2'-BETA-D-GLUCOSIDE;Phlorizin dihydrate USP/EP/BP;Phlorizin dihydrate (Standard);Phloretin 2'-b-D-glucopyranoside
- CBNumber:
- CB3331802
- Molecular Formula:
- C21H26O11
- Molecular Weight:
- 454.43
- MDL Number:
- MFCD00006591
- MOL File:
- 7061-54-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-22 20:19:50
| Melting point | 113-114 °C(lit.) |
|---|---|
| alpha | -52 º (c=3, EtOH) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Solid |
| color | White to off-white |
| biological source | apple wood |
| optical activity | [α]20/D 52°, c = 3 in ethanol |
| BRN | 66621 |
| InChIKey | XQWBNXSENPTIDY-YXMARJSJSA-N |
| SMILES | O.O.OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O |
| CAS DataBase Reference | 7061-54-3(CAS DataBase Reference) |
| FDA UNII | CRK54BIJ5D |
| UNSPSC Code | 85151701 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | UC2080000 |
| F | 3-10-23 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
Phlorizin dihydrate price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 274313 | Phloridzin dihydrate 99% | 7061-54-3 | 1g | $183 | 2026-04-30 | Buy |
| Sigma-Aldrich | 274313 | Phloridzin dihydrate 97% | 7061-54-3 | 5g | $873 | 2026-04-30 | Buy |
| Biosynth | MP74089 | Phloridzin dihydrate | 7061-54-3 | 50g | $207.5 | 2026-06-04 | Buy |
| Biosynth | MP74089 | Phloridzin dihydrate | 7061-54-3 | 100g | $363 | 2026-06-04 | Buy |
| Biosynth | MP74089 | Phloridzin dihydrate | 7061-54-3 | 250g | $715 | 2026-06-04 | Buy |
Phlorizin dihydrate Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from crabapple leaves and apple tree branches and leaves.
Uses
Phloridzin dihydrate has been used as:
- a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
- a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
- a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity
Biochem/physiol Actions
Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.
target
NO | PGE | NOS | COX
Phlorizin dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 188)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Chengdu Climax Biotech Co., Ltd. | 028-83311324 1278112614 | climaxbiotech@gmail.com | China | 925 | 58 |
View Lastest Price from Phlorizin dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Phlorizin dihydrate
7061-54-3
|
1kg | 0.99 | 1000kg | Shaanxi Xianhe Biotech Co., Ltd | ||
 |
2026-06-30 | Phlorizin dihydrate
7061-54-3
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-04-21 | Phlorizin dihydrate
7061-54-3
|
$29.00 | 98.41% | 10g | TargetMol Chemicals Inc. |
-
- Phlorizin dihydrate
7061-54-3
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Phlorizin dihydrate
7061-54-3
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Phlorizin dihydrate
7061-54-3
- $29.00
- 98.41%
- TargetMol Chemicals Inc.
7061-54-3(Phlorizin dihydrate)Related Search:
1of4
Phlorizin dihydrate
1-[2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate
1-[2,4-dihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]phenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate
2'-O-GLUCOSYL-4',6',4-TRIHYDROXYDIHYDROCHALCONE
1-[2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate
TIMTEC-BB SBB005924
PHLORETIN-2'-BETA-D-GLUCOSIDE
PHLORIDZIN
phloridzin from apple wood
1-[2-(β-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
PHLORIDZIN(RG)
Phlorizin dihydrate
Phloretin 2μ-β-D-glucopyranoside, Phloretin 2μ-β-D-glucoside, 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
Phloridzin dihydrate,1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Phloretin 2′-β-D-glucopyranoside, Phloretin 2′-β-D-glucoside, Phlorizin dihydrate
Phlorizin, Dihydrate, FroM Apple Wood
Phloridzin dihydrate 99%
Phloretin 2'-b-D-glucopyranoside
1-(2,4-Dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one dihydrate
Phlorizin dihydrate USP/EP/BP
1-Propanone,1-[2-(b-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-,dihydrate
Phlorizin dihydrate, 10 mM in DMSO
Phlorizin dihydrate (Standard)
7061-54-3
C21H24O10x2H2O
C21H24O102H2O
C21H28O12
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