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VPhos Pd G4

VPhos Pd G4 Structure
VPhos Pd G4 structure
CAS No.
1848244-57-4
Chemical Name:
VPhos Pd G4
Synonyms
VPhos Pd G4;Methanesulfonato(2- dicyclohexyl phosphine-2'-methoxy-4',6'-di-t-butylphosphino-1,1'-diphenyl) (2'-methylamino-1,1'-biphenyl-2-yl)palladium(II);Methanesulfonicacid{2-dicyclohexylphosphino-2'-methoxy-4',6'-di-tert-butyl-1,1'-biphenyl}(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II),VPhosPdG4;Methanesulfonato(2- dicyclohexyl phosphine-2'-methoxy-4',6'-di-t-butylphosphino-1,1'-diphenyl) (2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) (VPhos Pd G4);Methanesulfonato(2- dicyclohexyl phosphine-2'-methoxy-4',6'-di-t-butylphosphino-1,1'-diphenyl) (2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) (VPhos Pd G4)
CBNumber:
CB33375832
Molecular Formula:
C47H64NO4PPdS
Molecular Weight:
876.47
MDL Number:
MOL File:
1848244-57-4.mol
MSDS File:
SDS
Last updated:2026-07-30 08:05:27
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VPhos Pd G4 Properties

Melting point 160-162 °C
form powder or crystals
InChIKey VAPBXRPNLXSRPD-UHFFFAOYSA-N
SMILES P(C1CCCCC1)(C1CCCCC1)(C1C=CC=CC=1C1C(=CC(C(C)(C)C)=CC=1C(C)(C)C)OC)[Pd+2]1(N(C2=CC=CC=C2C2=CC=CC=[C-]12)C)[O-]S(=O)(=O)C
UNSPSC Code 12352202

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

VPhos Pd G4 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 901218 VPhos Pd G4 95% 1848244-57-4 1g $840 2023-06-20 Buy
Sigma-Aldrich 901218 VPhos Pd G4 95% 1848244-57-4 250mg $304 2023-01-07 Buy
aablocks AA02229K VPhos Pd G4 97% 1848244-57-4 100mg $137 2026-06-01 Buy
aablocks AA02229K VPhos Pd G4 97% 1848244-57-4 250mg $262 2026-06-01 Buy
aablocks AA02229K VPhos Pd G4 97% 1848244-57-4 1g $857 2026-06-01 Buy
Product number Packaging Price Buy
901218 1g $840 Buy
901218 250mg $304 Buy
AA02229K 100mg $137 Buy
AA02229K 250mg $262 Buy
AA02229K 1g $857 Buy

VPhos Pd G4 Chemical Properties, Uses, Production

Uses

Buchwald palladacycle precatalyst with new biaryl(dialkyl)phosphine ligand, VPhos, has an improved activity profile for the reductive coupling of non-aromatic heterocyclic alkyl bromides. Its combined use with a surfactant system of octanoic acid/sodium octanoate enables Negishi coupling and access to diverse C(sp3)–C(sp2) cross-coupled products.

It is a fourth-generation (G4) Buchwald precatalysts are similar to the third generation (G3) precatalysts except that the amino group on the biphenyl backbone is methylated. This modification helps to prevent the limitations of using the third generation precatalysts. It is air-, moisture-, and thermally stable and shows good solubility in common organic solvents.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

VPhos Pd G4 Preparation Products And Raw materials

Raw materials

Preparation Products

VPhos Pd G4 Suppliers

Global Suppliers ( 26)
Supplier Tel Email Country ProdList Advantage
xinxiang runyu material co.,Ltd 15690792173 sales@runvmat.com China 111 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9778 55
LaaJoo 021-60702684 18516024827 huang.jiayi@sinocompound.com China 2280 58
Jiaxing Deyi Chemical Co., Ltd. 86-0573-85866609 18367600069 945717149@qq.com China 9507 58
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418684 +86-18949823763 sales@tnjchem.com China 25333 58
HUNAN CHEMFISH SCIENTIFIC CO.,LTD 85521272 18932438858 sales@chemfish.com China 7780 58
Accela ChemBio Inc. +1-858-6993322 +86-18019713315 info@accelachem.com United States 21189 58
Yangzhou modier Electronic Materials Co., Ltd 13761402923 19975033992 market@modeltemol.com China 7847 58
xinxiang runyu material co.,Ltd 03737759608 15690792173 sales@runvmat.com China 300 58
Supplier Advantage
xinxiang runyu material co.,Ltd 58
Sigma-Aldrich 80
Tianjin Kailiqi Biotechnology Co., Ltd. 55
LaaJoo 58
Jiaxing Deyi Chemical Co., Ltd. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
HUNAN CHEMFISH SCIENTIFIC CO.,LTD 58
Accela ChemBio Inc. 58
Yangzhou modier Electronic Materials Co., Ltd 58
xinxiang runyu material co.,Ltd 58

View Latest Price from VPhos Pd G4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VPhos Pd G4 pictures 2026-08-25 VPhos Pd G4
1848244-57-4
 $2.00-5.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
VPhos Pd G4 pictures 2025-12-23 VPhos Pd G4
1848244-57-4
 1g 98% 500 XINXIANG RUNYU MATERIAL CO., LTD.
  • VPhos Pd G4 pictures
  • VPhos Pd G4
    1848244-57-4
  • $2.00-5.00
  • 99%
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
  • VPhos Pd G4 pictures
  • VPhos Pd G4
    1848244-57-4
  • 98%
  • XINXIANG RUNYU MATERIAL CO., LTD.

1848244-57-4 (VPhos Pd G4) Related Search:

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VPhos Pd G4 Methanesulfonato(2- dicyclohexyl phosphine-2'-methoxy-4',6'-di-t-butylphosphino-1,1'-diphenyl) (2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) Methanesulfonato(2- dicyclohexyl phosphine-2'-methoxy-4',6'-di-t-butylphosphino-1,1'-diphenyl) (2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) (VPhos Pd G4) Methanesulfonicacid{2-dicyclohexylphosphino-2'-methoxy-4',6'-di-tert-butyl-1,1'-biphenyl}(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II),VPhosPdG4 Methanesulfonato(2- dicyclohexyl phosphine-2'-methoxy-4',6'-di-t-butylphosphino-1,1'-diphenyl) (2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) (VPhos Pd G4) 1848244-57-4