1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
- CAS No.
- 1837-91-8
- Chemical Name:
- 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
- Synonyms
- NSC 7908;JAK2 INHIBITOR II;BENZENE HEXABROMIDE;6-Hexabromocyclohexane;trans-α-Benzene hexabromide;1,2,3,4,5,6-Hexabromcyclohexan;1,2,3,4,5,6-HEXABROMOCYCLOHEXANE;1,2,3,4,5,6-hexabromo-cyclohexan;Cyclohexane, 1,2,3,4,5,6-hexabromo-;JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem
- CBNumber:
- CB3337703
- Molecular Formula:
- C6H6Br6
- Molecular Weight:
- 557.54
- MDL Number:
- MFCD00059127
- MOL File:
- 1837-91-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| JAK2 Inhibitor II | 420132 | 25mg | $190 |
| 1,2,3,4,5,6-Hexabromocyclohexane ≥98% (HPLC) | SML0455 | 50mg | $127 |
| 1,2,3,4,5,6-Hexabromocyclohexane | H0368 | 5g | $326 |
| 1,2,3,4,5,6-Hexabromocyclohexane min. 97.0 % | H0368 | 1G | $109 |
| 1,2,3,4,5,6-Hexabromocyclohexane | H290033 | 250mg | $70 |
| Melting point | 218.0 to 223.0 °C |
|---|---|
| storage temp. | Store at RT |
| solubility | DMSO: soluble2mg/mL (clear solution, warmed) |
| form | powder |
| color | white to beige |
| InChI | 1S/C6H6Br6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H |
| InChIKey | QFQZKISCBJKVHI-UHFFFAOYSA-N |
| SMILES | BrC1C(C(C(C(C1Br)Br)Br)Br)Br |
| CAS DataBase Reference | 1837-91-8(CAS DataBase Reference) |
| EPA Substance Registry System | Cyclohexane, 1,2,3,4,5,6-hexabromo- (1837-91-8) |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P337+P313 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-36-22 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 420132 | JAK2 Inhibitor II | 1837-91-8 | 25mg | $190 | 2026-03-19 | Buy |
| Sigma-Aldrich | SML0455 | 1,2,3,4,5,6-Hexabromocyclohexane ≥98% (HPLC) | 1837-91-8 | 50mg | $127 | 2022-05-15 | Buy |
| TCI Chemical | H0368 | 1,2,3,4,5,6-Hexabromocyclohexane | 1837-91-8 | 5g | $326 | 2021-12-16 | Buy |
| TCI Chemical | H0368 | 1,2,3,4,5,6-Hexabromocyclohexane min. 97.0 % | 1837-91-8 | 1G | $109 | 2021-12-16 | Buy |
| TRC | H290033 | 1,2,3,4,5,6-Hexabromocyclohexane | 1837-91-8 | 250mg | $70 | 2021-12-16 | Buy |
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Chemical Properties,Uses,Production
Uses
1,2,3,4,5,6-Hexabromocyclohexane is a potent and specific inhibitor of JAK2 autophosphorylation.
Definition
ChEBI: 1,2,3,4,5,6-hexabromocyclohexane is a bromohydrocarbon that is cyclohexane in which the hydrogen at positions 1,2,3,4,5 and 6 have been replaced by bromo groups. It is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a bromohydrocarbon and a bromoalkane. It derives from a hydride of a cyclohexane.
Biological Activity
Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μ M of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μ M elimates nearly all JAK2 activity. Non-cytotoxic at 100 μ M.
storage
Room temperature
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Preparation Products And Raw materials
Raw materials
Preparation Products
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19957 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53802 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | 1,2,3,4,5,6-Hexabromocyclohexane
1837-91-8
|
US $0.00-0.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-09-25 | 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
1837-91-8
|
US $101.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 1,2,3,4,5,6-Hexabromocyclohexane
1837-91-8
- US $0.00-0.00 / mg
- TargetMol Chemicals Inc.
-
- 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
1837-91-8
- US $101.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
