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ChemicalBook >> CAS DataBase List >>N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide

N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide

N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide Structure
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide structure
CAS No.
780822-35-7
Chemical Name:
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
Synonyms
hsa62;N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide;1H-Benzimidazole-5-sulfonamide, 2,3-dihydro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthalenyl]-2-oxo-
CBNumber:
CB33445241
Molecular Formula:
C19H14N6O4S2
Molecular Weight:
454.48
MDL Number:
MOL File:
780822-35-7.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:07
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N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide Properties

Density 1.78±0.1 g/cm3(Predicted)
pka 6.82±0.50(Predicted)

N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA02TCQR N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide 780822-35-7 10mg $275 2026-06-03 Buy
Product number Packaging Price Buy
AA02TCQR 10mg $275 Buy

N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide Chemical Properties, Uses, Production

Uses

hsa62 is a dual inhibitor for SIRT1 and SIRT2, with IC50 of 1.3 and 5.5 μM, respectively[1].

IC 50

SIRT1: 1.3 μM (IC50); SIRT2: 5.5 μM (IC50); SIRT3: 43.6 μM (IC50)

References

[1] Cai H, et al., Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells. J Chem Inf Model. 2023 Aug 14;63(15):4780-4790. DOI:10.1021/acs.jcim.3c00556

N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58

780822-35-7 (N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide) Related Search:

Pyridine, 3-(1H-1,2,3-triazol-4-yl)- (9CI) gamma-Glu-Cys trifluoroacetate salt Nicotinamide Nicotinamide riboside chloride N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
Acetamide, 2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]-N-[5-[(4-nitrophenyl)sulfonyl]-2-thiazolyl]-

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N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide 1H-Benzimidazole-5-sulfonamide, 2,3-dihydro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthalenyl]-2-oxo- hsa62 780822-35-7 C19H14N6O4S2