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2-Chloro-5-nitrotoluene

CAS No.
13290-74-9
Chemical Name:
2-Chloro-5-nitrotoluene
Synonyms
2-Chloro-5-nit;oro-5-nitrotoL;Chloronitroluene,98%;2-Chloro-5-nitroluene;2-Chloro-5-nitrotolune;Toltrazuril Impurity B;2-CHLORO-5-NITROTOLUENE;5-NITRO-2-CHLOROTOLUENE;3-Nitro-6-chlorotoluene;2-Chloro-5-nitrotoluene >
CBNumber:
CB3346769
Molecular Formula:
C7H6ClNO2
Molecular Weight:
171.58
MDL Number:
MFCD00041430
MOL File:
13290-74-9.mol
MSDS File:
SDS
Last updated:2026-08-28 09:47:31

2-Chloro-5-nitrotoluene Properties

Melting point 40-44 °C
Boiling point 94-96°C 4mm
Density 1.3246 (rough estimate)
refractive index 1.5377 (estimate)
Flash point 94-96°C/4mm
storage temp. Sealed in dry,Room Temperature
form powder to crystal
color White to Yellow to Green
BRN 2044766
InChI 1S/C7H6ClNO2/c1-5-4-6(9(10)11)2-3-7(5)8/h2-4H,1H3
InChIKey BGDCQZFFNFXYQC-UHFFFAOYSA-N
SMILES Cc1cc(ccc1Cl)[N+]([O-])=O
CAS DataBase Reference 13290-74-9(CAS DataBase Reference)
EPA Substance Registry System 2-Chloro-5-nitrotoluene (13290-74-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS06,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H312-H331-H373-H401-H411-H302+H312+H332-H315-H319-H412
Precautionary statements  P261-P264-P270-P271-P273-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501-P260-P304+P340-P305+P351+P338-P405-P501a
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,N
Risk Statements  22-52/53
Safety Statements  22-36/37-61
RIDADR  UN 3457 6.1/PG 3
WGK Germany  3
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  2902900000
Storage Class 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications Acute Tox. 4 Oral
REACH Registrations Active
NFPA 704
1
2 0

2-Chloro-5-nitrotoluene price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1233 2-Chloro-5-nitrotoluene >98.0%(GC) 13290-74-9 25g $37 2026-04-30 Buy
TCI Chemical C1233 2-Chloro-5-nitrotoluene >98.0%(GC) 13290-74-9 500g $281 2026-04-30 Buy
Usbiological 267314 2-Chloro-5-nitrotoluene Asreported 13290-74-9 25g $392 2026-06-03 Buy
Usbiological 267314 2-Chloro-5-nitrotoluene Asreported 13290-74-9 50g $573 2026-06-03 Buy
Usbiological 267314 2-Chloro-5-nitrotoluene Asreported 13290-74-9 100g $822 2026-06-03 Buy
Product number Packaging Price Buy
C1233 25g $37 Buy
C1233 500g $281 Buy
267314 25g $392 Buy
267314 50g $573 Buy
267314 100g $822 Buy

2-Chloro-5-nitrotoluene Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-5-nitrotoluene can be used to synthesize diazo photosensitive materials, microwave photography, and other applications.

Synthesis

2-Methyl-4-nitroaniline

99-52-5

2-Chloro-5-nitrotoluene

13290-74-9

General procedure for the synthesis of 2-chloro-5-nitrotoluene from 4-nitro-2-methylaniline: First, 152 kg of 2-amino-5-nitrotoluene was dissolved in 600 kg of concentrated sulfuric acid, followed by the addition of 150 kg of water, and naturally heated to 100°C. After the reaction solution was completely dissolved, the temperature was lowered to 300 kg of industrial hydrochloric acid at a concentration of 30%. After 2-amino-5-nitrotoluene was completely dissolved, the temperature was lowered and 300 kg of industrial hydrochloric acid with a mass concentration of 30% was added, during which it was necessary to ensure that the temperature of the reaction solution did not exceed 0°C. The temperature of the reaction solution was then increased by 27 kg at a constant rate. Next, 276 kg of a 25% sodium nitrite solution was added at a constant rate to produce the diazonium salt solution. In another reactor, 450 kg of industrial hydrochloric acid was added and 225 kg of cuprous chloride was dissolved with stirring, and the temperature was reduced to below 20°C after dissolution. The prepared diazonium salt solution was quickly added to this reactor for rapid stirring and hydrolysis reaction. The reaction mixture was held for 2 hours before being warmed up to 55°C and maintained at this temperature for 2 hours. Finally, water vapor was distilled out by increasing the temperature until 160 kg of 2-chloro-5-nitrotoluene was collected in 93.3% yield.

References

[1] Patent: CN108373434, 2018, A. Location in patent: Paragraph 0032; 0033; 0035; 0036; 0037; 0040; 0041
[2] Chemische Berichte, 1887, vol. 20, p. 200
[3] Arzneimittel-Forschung/Drug Research, 1989, vol. 39, # 9, p. 1073 - 1080

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View Lastest Price from 2-Chloro-5-nitrotoluene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-nitrotoluene pictures 2026-09-02 2-Chloro-5-nitrotoluene
13290-74-9
$1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Chloro-5-nitrotoluene pictures 2026-06-30 2-Chloro-5-nitrotoluene
13290-74-9
1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Chloro-5-nitrotoluene  pictures 2020-02-26 2-Chloro-5-nitrotoluene
13290-74-9
1KG 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd
5-NITRO-2-CHLOROTOLUENE 4-CHLORO-3-METHYLNITROBENZENE 2-CHLORO-5-NITROTOLUENE 2-CHLORO-5-NITROMETHYLBENZENE BENZENE, 2-CHLORO-1-METHYL-5-NITRO- 2-Chloro-5-nitrotolune 2-CHLORO-1-METHYL-5-NITROBENZENE 1-chloro-2-methyl-4-nitro-benzen 2-Chloro-5-nitroluene Chloronitroluene,98% 2-CHLORO-5-NITROTOLUENE, 98+% 6-CHLORO-2-METHYLNITROBENZENE 2-Methyl-4-nitrochlorobenzene 3-Nitro-6-chlorotoluene 4-Chloro-3-methylnitrobenzene 5-Nitro-2-chlorotoluene 2-Chloro-5-nitrotoluene, 98.0%(GC) 2-Chloro-5-nit 2-Chloro-5-nitrotoluene >=99.0% (GC) oro-5-nitrotoL 2-Chloro-5-nitrotoluene > Benzene, 1-chloro-2-methyl-4-nitro- 2-Chloro-5-nitrotoluene ISO 9001:2015 REACH Toltrazuril Impurity B 2-Chloro-5-nitrotolueneQ: What is 2-Chloro-5-nitrotoluene Q: What is the CAS Number of 2-Chloro-5-nitrotoluene 2,4-Dichlorobenzyl Alcohol Impurity 54 Benzeneethanol,4-chloro-b-(4-chlorophenyl)- 1-chloro-2-methyl-4-nitrobenzene 13290-74-9 Nitro Compounds Organic Building Blocks Nitrogen Compounds Building Blocks Aromatic Hydrocarbons (substituted) & Derivatives Nitro Compounds Nitrogen Compounds Organic Building Blocks Halogen toluene Chlorine Compounds Nitro Compounds