Daltroban
- CAS No.
- 79094-20-5
- Chemical Name:
- Daltroban
- Synonyms
- BM-13505;DALTROBAN;SKF-96148;Daltroban USP/EP/BP;DatelliptiumChloride;Daltroban >98% (HPLC);Daltroban, 10 mM in DMSO;4-[2-(4-Chlorobenzene-sulfonamido)ethyl]benzeneacetic acid;4-[2-[(4-CHLOROPHENYLSULFONYL)AMINO]ETHYL]BENZENEACETIC ACID;2-[4-[2-(4-chlorophenyl)sulfonylaminoethyl]phenyl]acetic acid
- CBNumber:
- CB3384707
- Molecular Formula:
- C16H16ClNO4S
- Molecular Weight:
- 353.82
- MDL Number:
- MFCD00868295
- MOL File:
- 79094-20-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Daltroban >98% (HPLC) | D7441 | 5mg | $228 |
| Daltroban >98% (HPLC) | D7441 | 25mg | $857 |
| Daltroban ≥98% | 14061 | 1mg | $48 |
| Daltroban ≥98% | 14061 | 5mg | $190 |
| Daltroban ≥98% | 14061 | 10mg | $354 |
| Melting point | 132.5-137.4 °C(lit.) |
|---|---|
| Boiling point | 555.3±60.0 °C(Predicted) |
| Density | 1.378±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 22 mg/mL, soluble |
| pka | 4.33±0.10(Predicted) |
| form | A solid |
| color | white |
| InChI | InChI=1S/C16H16ClNO4S/c17-14-5-7-15(8-6-14)23(21,22)18-10-9-12-1-3-13(4-2-12)11-16(19)20/h1-8,18H,9-11H2,(H,19,20) |
| InChIKey | IULOBWFWYDMECP-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=CC=C(CCNS(C2=CC=C(Cl)C=C2)(=O)=O)C=C1 |
| CAS DataBase Reference | 79094-20-5(CAS DataBase Reference) |
| FDA UNII | S25VDY08ZC |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Daltroban price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7441 | Daltroban >98% (HPLC) | 79094-20-5 | 5mg | $228 | 2026-04-30 | Buy |
| Sigma-Aldrich | D7441 | Daltroban >98% (HPLC) | 79094-20-5 | 25mg | $857 | 2022-05-15 | Buy |
| Cayman Chemical | 14061 | Daltroban ≥98% | 79094-20-5 | 1mg | $48 | 2026-04-30 | Buy |
| Cayman Chemical | 14061 | Daltroban ≥98% | 79094-20-5 | 5mg | $190 | 2026-04-30 | Buy |
| Cayman Chemical | 14061 | Daltroban ≥98% | 79094-20-5 | 10mg | $354 | 2026-04-30 | Buy |
Daltroban Chemical Properties,Uses,Production
Description
Daltroban (BM 13505, SKF 96148), a specific thromboxane A2 receptor antagonist, was studied as an antithrombotic agent. Daltroban increases intracellular calcium in vascular smooth muscle cells. Daltroban shows a protective effect in reperfusion injury. The drug was licensed to Smith Kline Beecham and underwent phase III clinical trials in the UK and Germany as an antithrombotic agent but did not enter clinical trials in the USA. Besides, вaltroban was investigated in patients with an ischemic heart disorder. However, the development of daltroban has been discontinued.
Uses
Immunosuppressant.
Uses
Daltroban can be used as a2 receptor to target adipose-derived stem cell for treating ischemic diseases.
Uses
Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist that increases intracellular calcium ions in vascular smooth muscle cells and protects against reperfusion injury after myocardial ischaemia but not in coronary artery endothelial cells. Daltroban may also be useful in the treatment of patients with COPD-related pulmonary hypertension.
in vivo
Daltroban (BM-13505) (1 mg/kg; i.v.; per hour) exerts protective effect in reperfusion injury following acute myocardial ischemia in cats[2].
In comparison with vehicle (physiological saline)-treated cats, Daltroban (20 mg/kg per hour i.v.) reduces the ischaemia-induced rise in the ST segment and prevented the development of a Q-wave in the ECG during reperfusion. Daltroban protects the myocardium from ischaemic injury and that this effect involves prevention of ischaemia-induced leukocytosis[3].
| Animal Model: | Adult male cats (2.8 to 4.6 kg; anesthetized cat model)[2] |
| Dosage: | 1 mg/kg |
| Administration: | i.v.; 30 minutes before reperfusion at a rate of 1 mg/kg followed by 1 mg/kg/hour |
| Result: | Significantly reduced the area of ischemic tissue as a percent of total left ventricular mass and total area at risk, without altering basic hemodynamics and thereby not influencing myocardial oxygen demand. |
target
TXA2
IC 50
TXA2
Daltroban Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Daltroban Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28232 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2123 | 70 |
| Shanghai Fuhe Chemistry Technology Co., Ltd. | 0086-21-67651709 | cfx759@hotmail.com | China | 410 | 57 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4785 | 55 |
View Lastest Price from Daltroban manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-02 | Daltroban
79094-20-5
|
$53.00-196.00 | 99.66% | 10g | TargetMol Chemicals Inc. | ||
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2025-11-18 | Daltroban USP/EP/BP
79094-20-5
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
-

- Daltroban
79094-20-5
- $53.00-196.00
- 99.66%
- TargetMol Chemicals Inc.
-

- Daltroban USP/EP/BP
79094-20-5
- $1.10
- 99.9%
- Dideu Industries Group Limited





