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tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Structure
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate structure
CAS No.
1698027-20-1
Chemical Name:
tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate
Synonyms
1588-A4;ARS-1620 Intermediate;1588-A-4,1588A4,1588 A4;tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate;1-Piperazinecarboxylic acid, 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester
CBNumber:
CB33959797
Molecular Formula:
C17H19BrClFN4O2
Molecular Weight:
445.71
MDL Number:
MOL File:
1698027-20-1.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Properties

Boiling point 534.9±50.0 °C(Predicted)
Density 1.521±0.06 g/cm3(Predicted)
solubility DMSO: Slightly soluble: 0.1-1 mg/ml
pka 10.06±0.70(Predicted)

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 42439 1588-A4 ≥98% 1698027-20-1 5mg $28 2026-04-30 Buy
Cayman Chemical 42439 1588-A4 ≥98% 1698027-20-1 10mg $53 2026-04-30 Buy
Cayman Chemical 42439 1588-A4 ≥98% 1698027-20-1 50mg $248 2026-04-30 Buy
Cayman Chemical 42439 1588-A4 ≥98% 1698027-20-1 100mg $468 2026-04-30 Buy
aablocks AA01OSU0 tert-Butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate 1698027-20-1 1mg $63 2026-05-31 Buy
Product number Packaging Price Buy
42439 5mg $28 Buy
42439 10mg $53 Buy
42439 50mg $248 Buy
42439 100mg $468 Buy
AA01OSU0 1mg $63 Buy

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Chemical Properties, Uses, Production

Description

1588-A4 is a synthetic intermediate that has been used in the synthesis of the K-RasG12C inhibitor ARS1620 (Item No. 27915).1 WARNING This product is not for human or veterinary use.

References

[1] MATTHEW R JANES. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.[J]. Cell, 2018, 172 3: 578-589.e17. DOI: 10.1016/j.cell.2018.01.006

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Suppliers

Global Suppliers ( 59)
Supplier Tel Email Country ProdList Advantage
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
ChemShuttle, Inc. 0510-83588313-811 18800520310 sales@chemshuttle.com China 2999 62
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3833 58
Wuhan Kaymke Chemical Co., Ltd., 027-87342388 18086026008 sales@kaymke.com China 3539 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4860 55
Shanghai Uchem Inc. 15618758386 15618758386 sales3@myuchem.com China 1990 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Supplier Advantage
Nanjing Chemlin Chemical Co., Ltd 64
ChemShuttle, Inc. 62
Wuhan ariel chemical Co., LTD. 58
Wuhan Kaymke Chemical Co., Ltd., 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai Uchem Inc. 55
ShangHai Biochempartner Co.,Ltd 62
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Shanghai SuperLan Chemcial Technique Centre 58

View Latest Price from tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1588-A4 pictures 2026-08-08 1588-A4
1698027-20-1
 $32.00-98.00 98.59% 10g TargetMol Chemicals Inc.
  • 1588-A4 pictures
  • 1588-A4
    1698027-20-1
  • $32.00-98.00
  • 98.59%
  • TargetMol Chemicals Inc.

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate Spectrum

tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate(1698027-20-1)1HNMR

1698027-20-1 (tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate) Related Search:

2-Quinazolinecarboxylic acid, 7-bromo-6-chloro-4-[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]-8-fluoro- Methylmagnesium iodide 3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid, 3-(7-bromo-2-chloro-6,8-difluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate
1-Piperazinecarboxylic acid, 4-(7-bromo-2,6-dichloro-8-fluoro-4-quinazolinyl)-3-methyl-, 1,1-dimethylethyl ester, (3R)-

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1588-A4 tert-butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester ARS-1620 Intermediate 1588-A-4,1588A4,1588 A4 1698027-20-1 C17H19BrClFN4O2