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1,2-Bis(trimethylsilyloxy)cyclobutene

1,2-Bis(trimethylsilyloxy)cyclobutene structure

CAS No.: 17082-61-0

Chemical Name:: 1,2-Bis(trimethylsilyloxy)cyclobutene

Synonyms: 1,2-Bis((triMethylsilyl)oxy)cyclobut-1-ene;1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE;DK105;DK578;obutene;DKSI111;95+%(gc);oxy)cycL;Hexacosanoic acid ≥4-Aminomethylindole &ge

CBNumber:: CB3400436

Molecular Formula:: C10H22O2Si2

Molecular Weight:: 230.45

MDL Number:: MFCD00010798

MOL File:: 17082-61-0.mol

MSDS File:: SDS

Last updated:2026-09-12 18:52:01

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1,2-Bis(trimethylsilyloxy)cyclobutene Properties

Boiling point	58-59 °C2 mm Hg(lit.)
Density	0.897 g/mL at 25 °C(lit.)
refractive index	n20/D 1.435(lit.)
Flash point	142 °F
storage temp.	Inert atmosphere,2-8°C
solubility	sol hydrocarbons and ethers.
form	clear liquid
color	Colorless to Light yellow
Specific Gravity	0.87
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	1367530
InChI	InChI=1S/C10H22O2Si2/c1-13(2,3)11-9-7-8-10(9)12-14(4,5)6/h7-8H2,1-6H3
InChIKey	WOBRFSDEZREQAB-UHFFFAOYSA-N
SMILES	C1(O[Si](C)(C)C)CCC=1O[Si](C)(C)C
CAS DataBase Reference	17082-61-0(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

RIDADR

1993

WGK Germany

10-21

TSCA

HS Code

2931.90.6000

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	2
0		0

1,2-Bis(trimethylsilyloxy)cyclobutene price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	293830	1,2-Bis(trimethylsiloxy)cyclobutene ≥95%	17082-61-0	5g	$148	2023-01-07	Buy
TCI Chemical	B1768	1,2-Bis(trimethylsilyloxy)cyclobutene >94.0%(GC)	17082-61-0	1g	$58	2026-04-30	Buy
TCI Chemical	B1768	1,2-Bis(trimethylsilyloxy)cyclobutene >94.0%(GC)	17082-61-0	5g	$171	2026-04-30	Buy
Usbiological	263590	1,2-Bis(trimethylsilyloxy)cyclobutene Asreported	17082-61-0	1g	$460	2026-06-03	Buy
Usbiological	263590	1,2-Bis(trimethylsilyloxy)cyclobutene Asreported	17082-61-0	2g	$636	2026-06-03	Buy

Product number	Packaging	Price	Buy
293830	5g	$148	Buy
B1768	1g	$58	Buy
B1768	5g	$171	Buy
263590	1g	$460	Buy
263590	2g	$636	Buy

1,2-Bis(trimethylsilyloxy)cyclobutene Chemical Properties, Uses, Production

Chemical Properties

clear colorless liquid

Uses

1,2-Bis(trimethylsilyloxy)cyclobutene is a useful chemical reactant used in the preparation and biological activity of serine and threonine β-lactones as inhibitors of hepatitis A virus 3C cysteine proteinase.

Application

Used as a suitable reagent for annulation processes and 4-keto ester synthesis.

General Description

Photocycloaddition of 2-cyclohexenones to 1,2-bis(trimethyl-siloxy)cyclobutene has been studied. It undergoes Aldol condensation reaction with carbonyl compounds. It reacts with Br₂ to give cyclobutanedione.

Synthesis

1,2-Bis(trimethylsilyloxy)cyclobutene is prepared as a colorless liquid by acyloin condensation of Diethyl Succinate (dispersed Na in toluene or Et2O, reflux) using Chlorotrimethylsilane as trapping agent.

storage

Use in a fume hood; the compound is stable for years if stored in a tightly screw-capped bottle. Prolonged exposure to moist air leads to decomposition.

1,2-Bis(trimethylsilyloxy)cyclobutene Preparation Products And Raw materials

Raw materials

Preparation Products

2-(benzyloxy)cyclobutan-1-one 2-Methyl-1,3-cyclopentanedione 3-Hydroxy-2-phenylcyclopent-2-enone

1,2-Bis(trimethylsilyloxy)cyclobutene Suppliers

Global Suppliers ( 146)

Supplier	Tel	Email	Country	ProdList	Advantage
nanjing huayan chemical corp.	25-25-86661363 18951712139	ruishi@hychemm.com	China	65	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44566	61
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11775	60
Adamas Reagent, Ltd.	4006009262 13023226327	hmj@titansci.com	China	14098	59
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@163.com	China	280	58
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57

Supplier	Advantage
nanjing huayan chemical corp.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
3B Pharmachem (Wuhan) International Co.,Ltd.	69
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Beijing Ouhe Technology Co., Ltd	60
Adamas Reagent, Ltd.	59
Chemsky（shanghai）International Co.,Ltd.	58
Shandong Xiya Chemical Co., Ltd	57

View Latest Price from 1,2-Bis(trimethylsilyloxy)cyclobutene manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-07-02	1,2-Bis(trimethylsiloxy)cyclobutene >=95% 17082-61-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
	2019-07-06	1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE 17082-61-0	$1.00	1KG	99%	100	Career Henan Chemical Co

1,2-Bis(trimethylsiloxy)cyclobutene >=95%
17082-61-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE
17082-61-0
$1.00
99%
Career Henan Chemical Co

1,2-Bis(trimethylsilyloxy)cyclobutene Spectrum

1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE(17082-61-0)¹HNMR 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE(17082-61-0)Raman 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE(17082-61-0)IR

17082-61-0 (1,2-Bis(trimethylsilyloxy)cyclobutene) Related Search:

tert-Butyldimethylsilyl chloride N,N-Dimethyltrimethylsilylamine (N,N-Dimethylamino)triethylsilane (N,N-Dimethylamino)dimethylchlorosilane Isopropenyloxytrimethylsilane

1,2-Bis(trimethylsilyloxy)cyclobutene Vinyloxytrimethylsilane Trimethyl(propoxy)silane

1of2

1,2-Bis(triMethylsiloxy)cyclobutene >=95% 4-methoxy-2-vinylbenzenamine &ge 2-Chloro-1,3-thiazole &ge 2,6-diethylpyridine &ge 3-Bromo-5-ethyl-2-methylpyridine &ge (4-Methyl-1,3-thiazol-2-yl)methanol &ge Methyl 3-(3-bromophenyl)-3-oxopropanoate &ge tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate &ge Benzyl chloromethyl ether &ge 4-Aminomethylindole &ge Phenoxyethyl chloroformate &ge 1-Boc-4-cyclopropylaminopiperidine &ge 2-Ethyl-4-methyl-1H-imidazole-1-propanenitrile &ge 2-Bromo-3-methylpyridine &ge Hexacosanoic acid &ge 6-butylpyridin-2-amine &ge 5-Bromo-4-methylthiazole &ge BIS(TRIMETHYLSILOXY)CYCLOBUTENE 1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE PURUM 95+ % (GC) 1,2-BIS(TRIMETHYLSILYLOXY)CYCLOBUTENE, 9 5+% 1,2-Bis(trimethylsiloxy)cyclobutenepurum 95+%(gc) BIS(TRIMETHYLSILOXY)CYCLOBUTENE ,95% [1-Cyclobutene-1,2-diylbis(oxy)]bis[trimethylsilane] 1,2-Bis(trimethylsiloxy)-1-cyclobutene triMethyl({1-[(triMethylsilyl)oxy]cyclobut-2-en-1-yl}oxy)silane Ethylene glycol-monopentylether &ge 4-Hydroxymethylthiazole &ge Pentachloronitrobenzene &ge 2-Chloro-1-N-isopropylimidazole &ge 2-Chloro-1N-ethyl-imidazole &ge Diallyl pyrocarbonate &ge (Tetrahydropyran-2-yl)methylamine &ge Di-tert-butyl-N,N-diisopropylphosphoramidite &ge Cis-3-(4-Tert-Butoxycarbonylaminocyclohexyl)Propionic Acid &ge 4-Phenylpyrrolidine-3-methylcarboxylate &ge 3-Chloro-5-methylpyridazine &ge N-Methyl-4-hydroxymethylpiperidine &ge 4,5,6,7-Tetrahydrothieno[3,2-c]pyridine &ge 2-Bromo-5-fluoro-3-methylpyridine &ge Ethyl 2-bromo-2-(4-fluorophenyl)acetate &ge Ethyl 2-methylacetoacetate &ge trimethyl({2-[(trimethylsilyl)oxy]cyclobut-1-en-1-yl}oxy)silane 1-Methyl-piperidine-4-carbonitrile &ge 1,2-Bis(trimethylsilyloxy)cyclobutene > oxy)cycL obutene Cyclobutene, 1,2-bis[(trimethylsilyl)oxy]- DK105 DK578 trimethyl-(2-trimethylsilyloxycyclobuten-1-yl)oxy-silane DKSI111 1,2-Bis((trimethylsilyl)oxy)cyclobut-1-ene - [B3339] 1,2-BIS(TRIMETHYLSILOXY)CYCLOBUTENE 1,2-Bis((triMethylsilyl)oxy)cyclobut-1-ene 1,2-Bis(trimethylsilyloxy)cyclobutene 17082-61-0 Building Blocks