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Isoquinoline-4-carbaldehyde

Isoquinoline-4-carbaldehyde Structure
Isoquinoline-4-carbaldehyde structure
CAS No.
22960-16-3
Chemical Name:
Isoquinoline-4-carbaldehyde
Synonyms
RARECHEM AK ML 0134;4-Formylisoquinoline;4-Isoquinolinecarbaldehyde;ISOQUINOLINE-4-CARBALDEHYDE;4-ISOQUINOLINECARBOXALDEHYDE;Isoquinoline-4-carboxaldehyde;4-Isoquinolinecarboxaldehyde 97%;Isoquinoline-4-carbaldehyde ,98%;4-Isoquinolinecarboxaldehyde (7CI,8CI,9CI);Isoquinoline-4-carbaldehyde ISO 9001：2015 REACH
CBNumber:
CB3409590
Molecular Formula:
C10H7NO
Molecular Weight:
157.17
MDL Number:
MFCD00829440
MOL File:
22960-16-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:15
Product description Number Pack Size Price
4-Isoquinolinecarboxaldehyde 97% 737542 1g $120
Isoquinoline-4-carbaldehyde I918263 500mg $110
Isoquinoline-4-carbaldehyde I918263 100mg $60
Isoquinoline-4-carbaldehyde 98% JK503584 1g $106
Isoquinoline-4-carboxaldehyde OR60160 250mg $24
More product size
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Isoquinoline-4-carbaldehyde Properties

Melting point 101-106℃
Boiling point 331.7±15.0 °C(Predicted)
Density 1.223±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form solid
pka 3.49±0.10(Predicted)
Appearance White to yellow Solid
InChI InChI=1S/C10H7NO/c12-7-9-6-11-5-8-3-1-2-4-10(8)9/h1-7H
InChIKey RNQQJLYJLDQGGL-UHFFFAOYSA-N
SMILES C1C2=C(C=CC=C2)C(C=O)=CN=1
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn
Risk Statements  22-36-36/37/38-20/21/22
Safety Statements  26-36/37/39-22
RIDADR  2811
WGK Germany  3
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
NFPA 704
1
2 0

Isoquinoline-4-carbaldehyde price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 737542 4-Isoquinolinecarboxaldehyde 97% 22960-16-3 1g $120 2023-06-20 Buy
TRC I918263 Isoquinoline-4-carbaldehyde 22960-16-3 500mg $110 2021-12-16 Buy
TRC I918263 Isoquinoline-4-carbaldehyde 22960-16-3 100mg $60 2021-12-16 Buy
Frontier Specialty Chemicals JK503584 Isoquinoline-4-carbaldehyde 98% 22960-16-3 1g $106 2021-12-16 Buy
Apolloscientific OR60160 Isoquinoline-4-carboxaldehyde 22960-16-3 250mg $24 2021-12-16 Buy
Product number Packaging Price Buy
737542 1g $120 Buy
I918263 500mg $110 Buy
I918263 100mg $60 Buy
JK503584 1g $106 Buy
OR60160 250mg $24 Buy

Isoquinoline-4-carbaldehyde Chemical Properties,Uses,Production

Chemical Properties

Off-white to yellow or brown solid

Synthesis

4-Bromoisoquinoline

1532-97-4

N,N-Dimethylformamide

68-12-2

Isoquinoline-4-carbaldehyde

22960-16-3

Under nitrogen protection, 4-bromoisoquinoline (2.0 g, 9.6 mmol) was dissolved in 30 mL of redistilled tetrahydrofuran (THF) and cooled to -65°C. n-Butyllithium (4.0 mL, 10 mmol, 2.5 M solution in THF) was added slowly and dropwise. Maintaining this temperature, the reaction mixture was stirred for 30 min. Subsequently, N,N-dimethylformamide (730 mg, 10 mmol) was added dropwise and stirring was continued for 1 h at the same temperature. After completion of the reaction, 100 mL of saturated aqueous ammonium chloride solution was added to the mixture. The reaction mixture was extracted with ethyl acetate (50 mL × 3). The organic layers were combined, washed with 100 mL of brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (elution gradient: 0-100% ethyl acetate/petroleum ether) to give isoquinoline-4-carboxaldehyde (550 mg, yellow solid, yield: 36%).1H NMR (400 MHz, CDCl3): δ 10.41 (s, 1H), 9.45 (s, 1H), 9.22 (d, J = 8.4 Hz, 1H) 8.96 (s, 1H), 8.10 (d, J = 8.4 Hz, 1H), 7.96-7.92 (m, 1H), 7.76 (t, J = 8.4 Hz, 1H).

References

[1] Tetrahedron, 1998, vol. 54, # 35, p. 10317 - 10328
[2] European Journal of Organic Chemistry, 2009, # 26, p. 4458 - 4467
[3] Patent: US2017/37050, 2017, A1. Location in patent: Paragraph 0346-0349

Isoquinoline-4-carbaldehyde Preparation Products And Raw materials

Raw materials

Isoquinoline Bromine n-Butyllithium 4-Bromoisoquinoline N,N-Dimethylformamide
Tetrahydrofuran

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Preparation Products

(isoquinolin-4-yl)methanol

Isoquinoline-4-carbaldehyde Suppliers

Global( 152)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
HaBo Hong Kong Co., Limited. 		+86-25-18512596065 info@habotech.com CHINA 933 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29794 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
HaBo Hong Kong Co., Limited. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Dideu Industries Group Limited 		58

View Lastest Price from Isoquinoline-4-carbaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isoquinoline-4-carbaldehyde pictures 2026-03-20 Isoquinoline-4-carbaldehyde
22960-16-3
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
Isoquinoline-4-carbaldehyde pictures 2025-11-18 Isoquinoline-4-carbaldehyde
22960-16-3
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
Isoquinoline-4-carbaldehyde pictures 2023-12-04 Isoquinoline-4-carbaldehyde
22960-16-3
 US $0.00-0.00 / kg 0.10000000149011612kg 98% 100kg Huida Pharmaceutical Technology (Shanghai) Co., Ltd.

Isoquinoline-4-carbaldehyde Spectrum

Isoquinoline-4-carbaldehyde(22960-16-3)1HNMR

22960-16-3(Isoquinoline-4-carbaldehyde)Related Search:

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RARECHEM AK ML 0134 ISOQUINOLINE-4-CARBALDEHYDE 4-ISOQUINOLINECARBOXALDEHYDE 4-Isoquinolinecarboxaldehyde (7CI,8CI,9CI) Isoquinoline-4-carboxaldehyde Isoquinoline-4-carbaldehyde ,98% 4-Formylisoquinoline 4-Isoquinolinecarboxaldehyde 97% Isoquinoline-4-carbaldehyde ISO 9001：2015 REACH 4-Isoquinolinecarbaldehyde 22960-16-3 5470-80-5 Isoquinoline Derivertives Building Blocks Isoquinoline Carbonyl Compounds Heterocycles ALDEHYDE