2-Hydroxy-6-(trifluoromethyl)pyridine
- CAS No.
- 34486-06-1
- Chemical Name:
- 2-Hydroxy-6-(trifluoromethyl)pyridine
- Synonyms
- 6-TRIFLUOROMETHYLPYRIDIN-2-ONE;Picoxystrobin M3;2-Hydroxy-6-(trifL;2-Hydroxy-6-trifluoromethyl;2(1H)-Pyridinone, 6-(trifluor;6-(Trifluoromethyl)pyrid-2-one;6-(Trifluoromethyl)pyridin-ylol;6-TRIFLUOROMETHYL-PYRIDINE-2-OL;6-trifluoromethyl-1H-pyridin-2-one;2-HYDROXY-6-TRIFLUOROMETHYLPRIDINE
- CBNumber:
- CB3433719
- Molecular Formula:
- C6H4F3NO
- Molecular Weight:
- 163.1
- MDL Number:
- MFCD08061317
- MOL File:
- 34486-06-1.mol
- MSDS File:
- SDS
| Melting point | 124-126° |
|---|---|
| Boiling point | 223.7±40.0 °C(Predicted) |
| Density | 1.398±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.03±0.10(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C6H4F3NO/c7-6(8,9)4-2-1-3-5(11)10-4/h1-3H,(H,10,11) |
| InChIKey | XXRUAAOADAPPII-UHFFFAOYSA-N |
| SMILES | C1(=O)NC(C(F)(F)F)=CC=C1 |
| CAS DataBase Reference | 34486-06-1(CAS DataBase Reference) |
| FDA UNII | 81T56GP86W |
| EPA Substance Registry System | 2(1H)-Pyridinone, 6-(trifluoromethyl)- (34486-06-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H341 |
| Precautionary statements | P501-P202-P201-P264-P280-P302+P352-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P405 |
| Hazard Codes | T,Xi |
| Risk Statements | 36/37/38-36-25 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | 2811 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2933399990 |
| Limited Quantities | 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
2-Hydroxy-6-(trifluoromethyl)pyridine price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-H977575-500MG | 2-Hydroxy-6-trifluoromethylpyridine | 34486-06-1 | 500mg | $96 | 2026-06-03 | Buy |
| TRC | TRC-H977575-250MG | 2-Hydroxy-6-trifluoromethylpyridine | 34486-06-1 | 250mg | $84 | 2026-06-03 | Buy |
| TRC | TRC-H977575-100MG | 2-Hydroxy-6-trifluoromethylpyridine | 34486-06-1 | 100mg | $70 | 2026-06-03 | Buy |
| Apolloscientific | PC9263 | 2-Hydroxy-6-(trifluoromethyl)pyridine ≥95% | 34486-06-1 | 1g | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS31254 | 2-Hydroxy-6-trifluoromethylpyridine 95% | 34486-06-1 | 5g | $23 | 2026-06-04 | Buy |
2-Hydroxy-6-(trifluoromethyl)pyridine Chemical Properties, Uses, Production
Uses
2-Hydroxy-6-trifluoromethylpyridine
Synthesis
39890-95-4
34486-06-1
(3) 1500 g of tert-butanol, 140 g of potassium hydroxide and 2-chloro-6-trifluoromethylpyridine prepared in step (2) were added to a 3 L reaction flask, heated up to 70 °C, and the reaction was held for 8 hours. After completion of the reaction, tert-butanol was removed by distillation under reduced pressure, 550 g of ethyl acetate and 550 g of water were added and mixed with stirring. The organic layer was washed with 370 g of saturated brine and dried by adding 100 g of anhydrous sodium sulfate. The ethyl acetate was removed by rotary evaporation to obtain 172.4 g of crude product; (4) The crude product prepared in step (3) was dissolved in 150 g of ethyl acetate, heated to 70 °C and stirred. 1200 g of petroleum ether was added slowly dropwise and the mixture was cooled to 2°C after the dropwise addition was completed, solid crystals were precipitated and the solid was collected by filtration. The solid was washed with 50 g of petroleum ether and dried at 70 °C to give 131.2 g of 2-hydroxy-6-trifluoromethylpyridine as a light yellow solid powder in 80.8% yield.
References
[1] Patent: CN106866512, 2017, A. Location in patent: Paragraph 0014
[2] Patent: US5973159, 1999, A
[3] Patent: CN107759513, 2018, A. Location in patent: Paragraph 0017
2-Hydroxy-6-(trifluoromethyl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Junhe Pharmaceutical Co., Ltd | 18653300596 | 3989432235@qq.com | China | 298 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. | 21-54820552 17702105771 | 188738128@qq.com | China | 300 | 66 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from 2-Hydroxy-6-(trifluoromethyl)pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-06-30 | 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-03-20 | 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
34486-06-1 (2-Hydroxy-6-(trifluoromethyl)pyridine) Related Search:
1of4
