ChemicalBook >> CAS DataBase List >>(2R,3S)-N-Benzoyl-3-phenyl Isoserine

(2R,3S)-N-Benzoyl-3-phenyl Isoserine

CAS No.
132201-33-3
Chemical Name:
(2R,3S)-N-Benzoyl-3-phenyl Isoserine
Synonyms
N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE;taxol side chain;TAXOL(R) SIDE CHAIN;Paclitaxel Impurity 30;Paclitaxel Impurity N1;Taxol side chain alcohol;TAXOL SIDE CHAIN ACID(SH);SIDE CHAINS OF PACLITAXEL--4;(2R,3S)-3-Benzoylamino-2-Hydro;(2R,3S)-N-Benzoylphenylisoserine
CBNumber:
CB7172977
Molecular Formula:
C16H15NO4
Molecular Weight:
285.3
MDL Number:
MFCD00274633
MOL File:
132201-33-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:14:43

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Properties

Melting point 169-172 °C (lit.)
Boiling point 580.7±50.0 °C(Predicted)
Density 1.316±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly)
form Solid
pka 3.40±0.17(Predicted)
color White to Off-White
optical activity [α]20/D 40°, c = 1.0 in ethanol
Major Application peptide synthesis
InChI 1S/C16H15NO4/c18-14(16(20)21)13(11-7-3-1-4-8-11)17-15(19)12-9-5-2-6-10-12/h1-10,13-14,18H,(H,17,19)(H,20,21)/t13-,14+/m0/s1
InChIKey HYJVYOWKYPNSTK-UONOGXRCSA-N
SMILES O[C@H]([C@@H](NC(=O)c1ccccc1)c2ccccc2)C(O)=O
CAS DataBase Reference 132201-33-3(CAS DataBase Reference)
FDA UNII D998Q2WJCM
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29242990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

(2R,3S)-N-Benzoyl-3-phenyl Isoserine price More Price(71)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 444375 N-Benzoyl-(2R,3S)-3-phenylisoserine 98% 132201-33-3 500mg $385 2026-04-30 Buy
TRC TRC-B208550-500MG (2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3 500mg $264 2026-06-03 Buy
TRC TRC-B208550-1G (2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3 1g $485 2026-06-03 Buy
TRC TRC-B208550-100MG (2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3 100mg $132 2026-06-03 Buy
Usbiological 003365 (2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3 100mg $368 2026-06-03 Buy
Product number Packaging Price Buy
444375 500mg $385 Buy
TRC-B208550-500MG 500mg $264 Buy
TRC-B208550-1G 1g $485 Buy
TRC-B208550-100MG 100mg $132 Buy
003365 100mg $368 Buy

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.

Uses

The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.

reaction suitability

reaction type: solution phase peptide synthesis

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 159)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-83725681-603 China 4484 50
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66

View Lastest Price from (2R,3S)-N-Benzoyl-3-phenyl Isoserine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Benzoyl-(2R,3S)-3-phenylisoserine pictures 2026-04-22 N-Benzoyl-(2R,3S)-3-phenylisoserine
132201-33-3
$37.00-80.00 99.86% 10g TargetMol Chemicals Inc.
N-Benzoyl-(2R,3S)-3-phenylisoserine pictures 2022-01-26 N-Benzoyl-(2R,3S)-3-phenylisoserine
132201-33-3
1KG 97.0% 100 tons Honest Joy Holdings Limited
(2R,3S)-N-Benzoyl-3-phenyl Isoserine pictures 2020-01-18 (2R,3S)-N-Benzoyl-3-phenyl Isoserine
132201-33-3
$3.00 1KG 98% 1kg , 5kg, 50kg Career Henan Chemical Co
N-BENZOYL-(2R,3S)-3-AMINO-2-HYDROXY-3-PHENYL-PROPIONIC ACID TAXOL(R) SIDE CHAIN (2R,3S)-3-Benzoylamino-2-Hydro (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionacid Taxol side chain alcohol (2R, 3S)-3-BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONACID,98+% (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid SIDE CHAINS OF PACLITAXEL--4 (2R,3S)-2-Hydroxy-3-(benzoylamino)-3-phenylpropionic acid (2R,3S)-3-(Benzoylamino)-3-phenyl-2-hydroxypropanoic acid (2R,3S)-N-Benzoylphenylisoserine (2R,3S)-N-Benzoyl-3-phenyl Isoserine (2R,3S)-N-Benzoyl-3-phenylisoserine (2R,3S)-3-(benzoylaMino)-2-hydroxy-3-phenylpropanoate N-benzoyl-(3S,2R)-3-phenylisoserine (αR,βS)-β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid [R-(R*,S*)]-β-(benzoylaMino)-α-hydroxybenzenepropanoic Acid (2R,3S)-3-BenzaMido-2-hydroxy-3-phenylpropanoic acid N-Benzoyl-(2R,3S)-3-phenylisoserine (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid N-Benzoyl-(2R,3S)-3-phenylisoserine 98% TAXOL SIDE CHAIN ACID(SH) Paclitaxel Side Chain Impurity 1 Paclitaxel Impurity 30 taxol side chain Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (αR,βS)- (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoic Acid ((2R,3S)-N-Benzoyl-3-phenylisoserine) N-Benzoyl-(2R,3S)-3-phenylisoserine,taxol side chain Paclitaxel Impurity N1 N-Benzoyl-(2R,3S)-3-phenylisoserine, 10 mM in DMSO N-Benzoyl-(2R,3S)-3-phenylisoserine N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE 132201-33-3 132201-33-2 C6H5CONHCHC6H5CHOHCO2H Unnatural Amino Acid Derivatives Serine Derivatives Specialty Synthesis Peptide Synthesis Herb extract Serine Derivatives Peptide Synthesis Unnatural Amino Acid Derivatives Amino Acids & Derivatives Anti-virals Aromatics Intermediates & Fine Chemicals Pharmaceuticals