(2R,3S)-N-Benzoyl-3-phenyl Isoserine
- CAS No.
- 132201-33-3
- Chemical Name:
- (2R,3S)-N-Benzoyl-3-phenyl Isoserine
- Synonyms
- N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE;taxol side chain;TAXOL(R) SIDE CHAIN;Paclitaxel Impurity 30;Paclitaxel Impurity N1;Taxol side chain alcohol;TAXOL SIDE CHAIN ACID(SH);SIDE CHAINS OF PACLITAXEL--4;(2R,3S)-3-Benzoylamino-2-Hydro;(2R,3S)-N-Benzoylphenylisoserine
- CBNumber:
- CB7172977
- Molecular Formula:
- C16H15NO4
- Molecular Weight:
- 285.3
- MDL Number:
- MFCD00274633
- MOL File:
- 132201-33-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 169-172 °C (lit.) |
|---|---|
| Boiling point | 580.7±50.0 °C(Predicted) |
| Density | 1.316±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly) |
| form | Solid |
| pka | 3.40±0.17(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D 40°, c = 1.0 in ethanol |
| Major Application | peptide synthesis |
| InChI | 1S/C16H15NO4/c18-14(16(20)21)13(11-7-3-1-4-8-11)17-15(19)12-9-5-2-6-10-12/h1-10,13-14,18H,(H,17,19)(H,20,21)/t13-,14+/m0/s1 |
| InChIKey | HYJVYOWKYPNSTK-UONOGXRCSA-N |
| SMILES | O[C@H]([C@@H](NC(=O)c1ccccc1)c2ccccc2)C(O)=O |
| CAS DataBase Reference | 132201-33-3(CAS DataBase Reference) |
| FDA UNII | D998Q2WJCM |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
(2R,3S)-N-Benzoyl-3-phenyl Isoserine price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 444375 | N-Benzoyl-(2R,3S)-3-phenylisoserine 98% | 132201-33-3 | 500mg | $385 | 2026-04-30 | Buy |
| TRC | TRC-B208550-500MG | (2R,3S)-N-Benzoyl-3-phenyl Isoserine | 132201-33-3 | 500mg | $264 | 2026-06-03 | Buy |
| TRC | TRC-B208550-1G | (2R,3S)-N-Benzoyl-3-phenyl Isoserine | 132201-33-3 | 1g | $485 | 2026-06-03 | Buy |
| TRC | TRC-B208550-100MG | (2R,3S)-N-Benzoyl-3-phenyl Isoserine | 132201-33-3 | 100mg | $132 | 2026-06-03 | Buy |
| Usbiological | 003365 | (2R,3S)-N-Benzoyl-3-phenyl Isoserine | 132201-33-3 | 100mg | $368 | 2026-06-03 | Buy |
(2R,3S)-N-Benzoyl-3-phenyl Isoserine Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.
Uses
(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.
Uses
The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.
reaction suitability
reaction type: solution phase peptide synthesis
(2R,3S)-N-Benzoyl-3-phenyl Isoserine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4484 | 50 | |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
View Lastest Price from (2R,3S)-N-Benzoyl-3-phenyl Isoserine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-22 | N-Benzoyl-(2R,3S)-3-phenylisoserine
132201-33-3
|
$37.00-80.00 | 99.86% | 10g | TargetMol Chemicals Inc. | ||
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2022-01-26 | N-Benzoyl-(2R,3S)-3-phenylisoserine
132201-33-3
|
1KG | 97.0% | 100 tons | Honest Joy Holdings Limited | ||
![]() |
2020-01-18 | (2R,3S)-N-Benzoyl-3-phenyl Isoserine
132201-33-3
|
$3.00 | 1KG | 98% | 1kg , 5kg, 50kg | Career Henan Chemical Co |
-

- N-Benzoyl-(2R,3S)-3-phenylisoserine
132201-33-3
- $37.00-80.00
- 99.86%
- TargetMol Chemicals Inc.
-

- N-Benzoyl-(2R,3S)-3-phenylisoserine
132201-33-3
- $0.00
- 97.0%
- Honest Joy Holdings Limited
-

- (2R,3S)-N-Benzoyl-3-phenyl Isoserine
132201-33-3
- $3.00
- 98%
- Career Henan Chemical Co





