- LUPENONE
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- $55.00
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2026-07-27
- CAS:1617-70-5
- Purity: 99.92%
- Supply Ability: 10g
- LUPENONE
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- $1.00
-
2019-07-06
- CAS:1617-70-5
- Min. Order: 1 mg
- Purity: 99%
- Supply Ability: 100KG
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| | Lupenone Basic information |
| Product Name: | Lupenone | | Synonyms: | Aids-082905;18-LUPEN-3-ONE;-en-3-one;Lup-20(29);LUPENONE(RG);5α-Lup-20(29)-en-3-one;Lupa-20(29)-ene-3β-one;Lupa-20(30)-ene-3-one | | CAS: | 1617-70-5 | | MF: | C30H48O | | MW: | 424.7 | | EINECS: | | | Product Categories: | Building block | | Mol File: | 1617-70-5.mol |  |
| | Lupenone Chemical Properties |
| Melting point | 165-167°C | | Boiling point | 485.7±14.0 °C(Predicted) | | density | 1.115 g/cm3(Temp: 18 °C) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | White | | LogP | 10.400 (est) |
| Hazard Codes | Xi | | HS Code | 29142990 |
| | Lupenone Usage And Synthesis |
| Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dandelion, bamboo leaves and Adenophora australis. | | Uses | Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor. | | Definition | ChEBI: A natural product found in Cupania cinerea. | | in vivo | Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis[2].
| Animal Model: | Spontaneous type 2 diabetic nephropathy db/db mouse models[1] | | Dosage: | 6, 12, 24 mg/kg | | Administration: | i.g. | | Result: | Maintained the fasting blood glucose.
Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels.
Regulated changes in biochemical indicators
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| | IC 50 | Trypanosoma |
| | Lupenone Preparation Products And Raw materials |
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